
Chronic cannabis use linked to thinner frontal brain region and reduced motivation, study finds
A study of 46 adults with long-term daily cannabis use (average about a decade; at least five years of daily use) found thinning of the right rostral middle frontal cortex on MRI, a region involved in planning and executive function. Researchers say such changes may be tied to reduced motivation and difficulty with complex tasks, but caution that causation isn’t proven and more research is needed to determine permanence or reversibility after stopping use.













