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Intismeran

All articles tagged with #intismeran

finance9 days ago•31 min saved

Moderna's cancer vaccine breakthrough could reshape its growth trajectory

Moderna's stock surged about 177% after news that its personalized mRNA cancer vaccine intismeran, in combination with Merck's Keytruda, reduced melanoma recurrence in a Phase 3 trial, signaling a potential shift for the biotech beyond infectious disease. Analysts from Jefferies, Bank of America, Citi, and JPMorgan call the result a watershed for Moderna's oncology outlook, with upside if label expansions and cross-indication uptake materialize, though questions remain about dataset completeness and commercial adoption. Fuller data and presentations are expected at the upcoming ESMO meeting, while the stock cooled slightly in premarket trading after yesterday's rally.

via Yahoo Finance|

#cancer #finance #intismeran

business9 days ago•2 min saved

Moderna and Merck's mRNA cancer vaccine shows promising melanoma results, lifting shares

Moderna and Merck reported that their experimental mRNA cancer vaccine, intismeran, when combined with Merck’s Keytruda, produced a clinically meaningful improvement in high-risk melanoma across more than 1,100 patients, with safety consistent with prior studies; the trial could pave the way for a commercial launch next year and signals potential for an expanded mRNA cancer platform, triggering a sharp rally in Moderna’s stock and a solid gain for Merck.

via axios.com|

#business #intismeran #keytruda

health9 days ago•2 min saved

Moderna-Merck mRNA vaccine shows promise in delaying melanoma recurrence

Moderna and Merck report interim Phase 3 results suggesting their personalized mRNA cancer vaccine Intismeran, used with Keytruda after melanoma surgery, may delay cancer recurrence in high-risk patients; data have not yet been peer‑reviewed and will be presented at a medical meeting and shared with regulators as the trial continues to assess overall survival.

via NBC News|

#health #immunotherapy #intismeran

health2 months ago•42 min saved

Personalized mRNA Vaccine Plus Immunotherapy Cuts Melanoma Recurrence by Half

A phase 2b trial (KEYNOTE-942) shows adding the personalized mRNA vaccine intismeran to pembrolizumab after melanoma surgery reduces recurrence or death by 49% over five years. The combo also lowers distant metastasis risk by 59% and yields 92.2% overall survival versus 71.3% with pembrolizumab alone. Five-year follow-up found 68.8% cancer-free in the combo group vs 50.9% in controls. The study, conducted in the US and Australia with 107 patients in the combo arm and 50 in control, reported manageable side effects and is guiding a phase 3 trial, with Moderna and Merck funding.

via Good News Network|

#cancer-vaccine #health #immunotherapy