All articles tagged with #micrornas
A mouse study shows a simple intranasal spray delivering stem-cell–derived particles with microRNAs reduces brain inflammation, restores mitochondrial energy, and improves memory, suggesting a noninvasive approach to slowing or reversing age-related brain decline—pending human testing.
A preclinical mouse study reports a nasal spray that delivers extracellular vesicles containing microRNAs to the brain can reverse signs of brain ageing within weeks, lowering inflammation and boosting cognitive processing. Two doses showed benefits, suggesting the brain’s repair systems can be reactivated, but more research and human trials are needed.
A new study published in Nature Communications reveals that deleting six specific microRNAs can override the influence of sex chromosomes, transforming male mice (with XY chromosomes) into females by delaying the production of a crucial protein. This discovery adds complexity to our understanding of sex determination in mammals and suggests that similar mechanisms may exist in other vertebrates, including humans.
Researchers at NYU Abu Dhabi have discovered microRNAs associated with weakened immune response and severe COVID-19 symptoms in a genetically diverse group of unvaccinated patients from underrepresented regions. The study offers new insights for patient prognosis, treatment, and the potential use of microRNAs as biomarkers for disease severity. The findings demonstrate that a patient's genetic makeup affects immune function and disease severity, offering new insights into how patient prognosis and treatment can be improved.
Researchers have identified specific microRNAs associated with weakened immune response and ICU admission in unvaccinated COVID-19 patients from the Middle East, North Africa, and South Asia. The study provides the first genomic blueprint of blood microRNAs in COVID-19 patients from these regions and could lead to improved patient prognosis and treatment strategies. The findings suggest that a patient's genetic makeup affects immune function and disease severity, offering new insights into how patient prognosis and treatment can be improved.