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Pde5 Inhibitors

All articles tagged with #pde5 inhibitors

health2 days ago•7 min saved

Regular Cialis Use Linked to Modest Glaucoma Risk, Study Finds

An observational study of 36,927 men aged 40+ found that regular tadalafil use over five years was associated with a higher glaucoma diagnosis rate (3.93% vs 3.16% in non-users), a 22% relative increase with an absolute difference of about 0.77 percentage points. The study cannot prove causation, and researchers note that the overall risk remains small; patients using tadalafil long-term should discuss eye monitoring with a clinician rather than stopping the medication.

via ScienceAlert|

#eye-health #glaucoma #health

health19 days ago•2 min saved

Big Study Finds Long-Term Cialis Use May Increase Glaucoma Risk

A large observational study of about 74,000 men aged 40+ with lower urinary tract symptoms found long-term tadalafil use was associated with higher risks of glaucoma (22%), elevated intraocular pressure (32%), and primary open-angle glaucoma (33%) over up to five years, though causation cannot be established. The findings suggest regular eye monitoring for long-term Cialis users, especially those with glaucoma risk factors; patients should not stop the medication without medical advice.

via FOX 13 Tampa Bay|

#cialis #eye-health #glaucoma

Popular ED Drug Linked to Small Increase in Glaucoma Risk

health25 days ago•2 min saved

Long-Term PDE5 Inhibitor Use Tied to Increased Glaucoma Risk

A large observational study of 73,854 men found that long-term tadalafil use for urinary symptoms was associated with higher odds of glaucoma (22%), ocular hypertension (32%), and starting glaucoma treatment (33%) over five years, compared with non-users. While the study cannot prove causation and has limitations (e.g., limited ethnic diversity), researchers advise baseline eye exams and regular eye monitoring for long-term users, especially those with glaucoma risk factors.

via SciTechDaily|

#eye-health #glaucoma #health

health6 months ago•57 min saved

Soft morning erections could signal hidden heart trouble, doctors warn

A Health feature explains that erectile dysfunction can be an early warning sign of cardiovascular disease, with reduced night-time erections and less rigidity as early clues; underlying issues like high cholesterol, hypertension, diabetes, and obesity may be involved, and lifestyle changes (more exercise, Mediterranean-style diet, good sleep) plus medical treatments (Viagra/Cialis and vacuum devices) can help improve function and potentially avert serious health problems.

via Daily Mail|

#cardiovascular-risk #erectile-dysfunction #health

health2 years ago•1 min saved

"Viagra and Cialis: Potential Alzheimer's Risk Reduction"

A study found that men prescribed Viagra and similar PDE5 inhibitor drugs were 18% less likely to develop Alzheimer's over a five-year period, with a 44% lower risk for those receiving 21 to 50 prescriptions. However, the study only found correlation, not causation, and it's unclear whether the pills offer protection against Alzheimer's or if men with lower disease risk are more likely to take Viagra. Researchers suggest a randomized controlled trial as the next step.

via Newser|

#alzheimers #erectile-dysfunction #health

health2 years ago•3 min saved

Study Suggests Viagra Reduces Alzheimer's Risk

A study suggests that men prescribed Viagra and similar medications may have a lower risk of developing Alzheimer's disease, with those receiving more prescriptions showing a 44% lower risk. However, it's unclear whether the drugs directly protect against Alzheimer's or if men less prone to the condition are more likely to use the tablets. The findings prompt the need for a clinical trial to investigate the effects of these drugs on Alzheimer's in both men and women. Repurposing existing drugs for dementia prevention could offer a promising strategy, but challenges exist in conducting placebo-controlled trials due to the drugs' prominent effects.

via The Guardian|

#alzheimers-disease #clinical-trial #dementia

health3 years ago•5 min saved

Cardiovascular Benefits of Erectile Dysfunction Drugs.

Sildenafil and tadalafil, the two most popular medications for erectile dysfunction (ED), may have substantial cardiovascular benefits for men with ED and concurrent heart disease. Both drugs significantly reduced the likelihood of progression to heart failure, myocardial infarction (MI), and death after 5 years as compared with men taking neither drug. Tadalafil had a more pronounced effect on all three clinical events than did sildenafil. A review of a large insurance database showed no consistent association between PDE5 inhibitor use and ocular events.

via Medpage Today|

#cardiovascular-disease #erectile-dysfunction #health

health3 years ago•1 min saved

New nasal spray for erectile dysfunction rivals Viagra in speed.

Australian researchers have developed a nasal spray called SPONTAN to combat erectile dysfunction, which works in as little as five minutes and could be rolled out to American consumers within two years. The spray repurposes the PDE5 inhibitor Vardenafil, which is taken orally one to two hours before sexual activity. A clinical trial will soon begin in Australia to compare the results of SPONTAN against the results of a different PDE5 inhibitor that will be taken orally. LTR Pharma has “very high confidence” that the results will be a success and wants the product to hit the US market in 2025.

via New York Post |

#clinical-trial #erectile-dysfunction #health