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Arpa H

All articles tagged with #arpa h

health10 days ago•3 min saved

Regenerative Joint Therapies Reversing Osteoarthritis in Weeks, Aiming for Human Trials

Colorado researchers report two regenerative therapies that reversed osteoarthritis signs in animals within 4–8 weeks: an injectable drug-delivery system using a repurposed FDA-approved drug and a biomaterial that recruits body-progenitor cells to repair cartilage. Backed by ARPA-H’s NITRO program with up to $33.5 million, the team has moved from phase one to phase two, with potential human trials in about 18 months and plans for commercial development through Renovare Therapeutics.

via ScienceDaily|

#arpa-h #clinical-trials #health

health18 days ago•8 min saved

HHS Unveils Bold Plan to Reclaim U.S. Leadership in Clinical Trials

The Department of Health and Human Services today launched a department-wide effort to restore U.S. leadership in clinical research, accelerate drug development, and expand patient access to innovative therapies. Key moves include FDA pilots to shorten early-trial timelines and clarify expectations, NIH support for AI-enabled, well-powered trials, NCATS’ translational advances, NCI’s streamlined trial activation and enrollment, ONC’s patient-trial matching via electronic health records, and ARPA-H initiatives to modernize research—all aimed at reducing delays and strengthening domestic biomedical leadership.

via HHS.gov|

#arpa-h #clinical-trials #fda

health1 month ago•8 min saved

Regenerative OA Therapies Rebuild Joints in Weeks, Near Clinical Trials

In animal studies, two regenerative approaches—a single injectable that releases medication over months and a biomaterial scaffold that recruits body’s progenitor cells—repaired damaged cartilage and bone within 4–8 weeks, with ARPA-H funding advancing the project toward clinical trials in about 18 months, aiming for affordable, minimally invasive, single-visit therapies that could eventually reduce the need for joint replacement.

via SciTechDaily|

#arpa-h #biomaterials #clinical-trials

politics2 months ago•3 min saved

Trump Admin Fast-Tracks Psychedelic Therapies for Serious Mental Illness

Trump signs an executive order to accelerate psychedelic therapies for serious mental illness, directing FDA to use national priority vouchers for breakthrough psychedelic drugs, create pathways to access investigational psychedelics under the Right to Try Act, and invest $50 million via ARPA-H to boost research; the plan calls for VA and private‑sector collaboration to expand trials and aims to help veterans and reduce suicide, building on prior Right to Try and drug research reforms.

via The White House (.gov)|

#arpa-h #executive-order #mental-health-treatment

science3 months ago•10 min saved

Salk to Lead $41M ARPA-H Initiative to Make Ultrasound-Controlled Therapies a Reality

Salk Institute researcher Sreekanth Chalasani will lead a multi-institution ARPA-H program, funded up to $41.3 million over about 5.5 years, to advance sonogenetics—the use of ultrasound to control engineered cells—into a clinical therapy by building a protein toolkit, a wearable ultrasound delivery system, and preclinical data across partner sites toward trials, with potential applications such as peripheral neuropathies.

via Salk Institute for Biological Studies|

#arpa-h #peripheral-neuropathy #science

health2 years ago•1 min saved

"Jill Biden Secures $100M for Women's Health R&D, Visits Connecticut"

Jill Biden announced $100 million in federal funding for women's health research through the ARPA-H Sprint for Women’s Health, aiming to address the underfunding and lack of research in women's health. The initiative seeks to prioritize women's health in the healthcare system and support groundbreaking research and development for women's health issues, with a focus on addressing chronic conditions and improving overall well-being.

via The Associated Press|

#arpa-h #health #jill-biden

health-research2 years ago•3 min saved

"First Lady Jill Biden Unveils $100 Million ARPA-H Sprint for Women’s Health Research"

First Lady Jill Biden announced the launch of the $100 million ARPA-H Sprint for Women’s Health, aiming to fund life-changing research in women’s health over the next year. The initiative seeks to address the underfunding and lack of focus on women's health research, aiming to invest in early discoveries and provide funding for women's health researchers and startups to bring their ideas to market. The goal is to accelerate advancements in women's healthcare and build a system that prioritizes women's experiences and health needs.

via The White House|

#arpa-h #health-research #jill-biden

health2 years ago•2 min saved

Dallas and Cambridge Chosen as National Hubs for $2.5 Billion Federal Health Research Agency

Dallas has been selected as one of three national hubs for the Advanced Research Projects Agency for Health (ARPA-H), a new federal agency focused on advancing breakthroughs in science and medicine. ARPA-H aims to prevent and treat diseases like cancer, Alzheimer's, and diabetes. Dallas will serve as the customer experience hub, tasked with developing accessible and readily adopted health solutions, including diversifying clinical trials and reaching demographically representative patient populations. The selection of Dallas comes after advocacy from Texas representatives and senators. The agency's goal is to extend its reach beyond the hub cities and states to promote inclusivity and innovation in healthcare.

via The Texas Tribune|

#arpa-h #dallas #health

science-and-technology2 years ago•5 min saved

Dallas Secures Coveted ARPA-H Hub, Outshining Houston in Federal Health Research Initiative

Dallas has been chosen as one of the three headquarters for the Advanced Research Projects Agency for Health (ARPA-H), a federal biotech research agency with a $2.5 billion budget. The decision comes after months of campaigning by Texas cities, universities, and science advocates. The Dallas hub, located at Pegasus Park, will focus on customer experience, access, and diversifying clinical trials for ARPA-H projects. The Texas consortium also includes Austin, San Antonio, and Houston, with stakeholders in El Paso and College Station supporting the statewide team. The announcement also introduced ARPANET-H, a "hub and spoke" model that includes spoke sites across the country. This win solidifies Dallas' position as a major life sciences hub and is expected to bring jobs and economic development to the region.

via The Dallas Morning News|

#arpa-h #biotech-research #dallas

health2 years ago•8 min saved

Millions in Federal Funding and Research Grants Aim to Revolutionize Cancer Treatment

The Advanced Research Projects Agency for Health (ARPA-H) has awarded $45 million to a Rice University-led team of researchers to develop a sense-and-respond implant technology called HAMMR that could potentially reduce U.S. cancer-related deaths by over 50%. The implant will continuously monitor a patient's cancer and adjust their immunotherapy dose in real time, aiming to improve outcomes for patients with difficult-to-treat cancers such as ovarian and pancreatic cancer. The THOR project involves a multidisciplinary team of experts from various fields and includes funding for a first-phase clinical trial for recurrent ovarian cancer.

via Rice News|

#arpa-h #cancer-treatment #health

health2 years ago•2 min saved

"Biden's Cancer Moonshot: $24M Investment in mRNA Tech to Strengthen Immune System and Save Lives"

The Biden Cancer Moonshot has launched the CUREIT project, led by Emory University, to develop mRNA platforms that can train the immune system to fight cancer and other diseases. With up to $24 million in funding from ARPA-H, the project aims to create a toolbox of mRNA technologies that can enhance immune responses, potentially revolutionizing the fight against cancer and other difficult diseases. This is the first award from ARPA-H's Open Broad Agency Announcement, with future projects to be funded on a rolling basis.

via The White House|

#arpa-h #cancer-moonshot #cureit

health3 years ago•3 min saved

"Biden's 'Moonshot' Initiative: Advanced Cancer Research Takes Center Stage"

The Biden administration has announced the launch of the Precision Surgical Interventions program, the first cancer-focused initiative under its advanced health research agency, ARPA-H. The program aims to improve cancer outcomes by developing better surgical interventions to treat the disease. ARPA-H, modeled after DARPA, will seek ideas from the public and private sectors to help surgeons distinguish between cancerous cells and healthy tissue during surgery. The initiative is part of Biden's bipartisan "cancer moonshot" effort to combat cancer, improve veterans' health, and make mental health more accessible. The agency is hosting an event in September to identify and approve projects, and it has also placed an open call for other research objectives.

via The Associated Press|

#arpa-h #biden-administration #cancer-moonshot