Tag

Suicidal Ideation

All articles tagged with #suicidal ideation

mental-health27 days ago•32 min saved

One-Dose Psilocybin Sparks Months of Relief From Suicidal Thoughts in Depression Study

A small open-label trial of 20 adults with treatment-resistant major depressive disorder found that a single 25 mg dose of synthetic psilocybin, with psychological support, rapidly reduced chronic suicidal thoughts and produced durable improvements over 12 weeks: 75% met criteria for a positive anti-suicidal response and 45% achieved remission by week 3, with depression scores also remaining low; however, lack of a control group, small sample size, and concurrent medication changes limit generalizability, underscoring the need for larger randomized trials.

via PsyPost|

#depression #mental-health #open-label-trial

mental-health5 months ago•20 min saved

Post-2016 spike: Depression symptoms rise among U.S. college students, especially among women and minorities

A large analysis of 560,000 students from 450 colleges (Healthy Minds Study, 2007–2022) shows depression symptoms increased across all PHQ-9 items, with the steepest rise after 2016 and the average nearing moderate depression by 2022. Suicidal ideation rose the most; increases were larger among women, intersex and racial minority students and those under financial stress. Cognitive symptoms rose more uniformly across groups, while physical symptoms grew more in minority groups. The study notes cross-sectional, self-reported data and calls for targeted campus suicide prevention and further exploration of macro-level drivers behind youth distress.

via PsyPost|

#college-students #depression #financial-stress

health2 years ago•7 min saved

"Suicidal Ideation and Hair Loss: Safety of GLP-1 Weight Loss Drugs Evaluated by FDA"

The FDA is investigating potential side effects of GLP-1 medications, including suicidal ideation, hair loss, and aspiration. While a recent study found no link between semaglutide, the active ingredient in drugs like Ozempic and Wegovy, and suicidal ideation, previous research has shown potential side effects such as gastrointestinal issues and increased heart rate. Experts suggest screening for psychological disorders before prescribing these medications and emphasize the importance of continuous monitoring and discussion of potential side effects with a healthcare provider.

via Medical News Today|

#fda #glp-1-medications #hair-loss

health2 years ago•6 min saved

"Study Finds No Increased Suicidal Ideation Risk with Diabetes, Weight Loss Drugs Ozempic and Wegovy"

A comprehensive review of U.S. health records, supported by the National Institutes of Health, found that semaglutide, marketed as Ozempic for diabetes and Wegovy for weight loss, is not associated with an increased risk of suicidal ideation compared to other medications for these conditions. The study, which included data from over 100 million patient records, showed a lower incidence of suicidal thoughts among semaglutide users. Despite the positive findings, researchers caution against off-label use of the drug for preventing suicidal ideation, suggesting that more clinical trials are needed to explore this potential use.

via CNN|

#health #mental-health #ozempic

health2 years ago•6 min saved

Blood Testing Reveals Metabolic Biomarkers Linked to Depression and Suicidal Thoughts

Researchers have identified specific blood metabolites that differ in people with depression, particularly in treatment-refractory cases and those with suicidal ideation. The study highlights sex-based differences in depression's metabolic impact and suggests that mitochondrial dysfunction plays a role in suicidal thoughts. These findings offer new avenues for personalized treatment and prevention strategies, potentially utilizing metabolic supplements like folate and carnitine to address metabolic gaps. The research could also help identify individuals at higher risk of becoming suicidal and lead to the development of new drugs targeting mitochondrial dysfunction.

via Neuroscience News|

#biomarkers #depression #health

mental-health-research2 years ago•2 min saved

Advancements in Schizophrenia Research: October 20 Update

New studies on schizophrenia reveal that middle-aged and elderly patients with good visuospatial ability and attention function are more likely to experience suicidal ideation, highlighting the need for targeted interventions. Smoking cigarettes is associated with lower serum concentrations of olanzapine in patients with schizophrenia, potentially leading to subtherapeutic effects. Insomnia symptoms in patients with schizophrenia are linked to impaired language abilities, suggesting that addressing insomnia could enhance cognitive function and quality of life.

via Psychiatric Times|

#insomnia #language-abilities #mental-health-research

health2 years ago•6 min saved

The Dark Side of Ozempic: Suicidal Thoughts and Disappointing Results

Some individuals who have taken the weight-loss drug Ozempic (semaglutide) have reported experiencing mental health issues, including anxiety, depression, and suicidal thoughts. The drug, which is prescribed for type 2 diabetes but is also used off-label for weight loss, has been associated with disturbing side effects such as premature aging, stomach paralysis, and spontaneous diarrhea. Reports of depression and suicide-related mental illnesses connected to Ozempic have been received by the US Food and Drug Administration, prompting an investigation by European drug safety regulators. Experts emphasize the importance of comprehensive care, monitoring physical and mental health, and setting realistic expectations for patients taking weight-loss medications.

via New York Post |

#health #mental-health #ozempic

mental-health3 years ago•5 min saved

Unveiling the Link Between Neural Responses and Suicidal Ideation

The way the brain responds to rewards and losses may serve as a brain-based marker for suicidal ideation in individuals with depression and social anxiety, according to a study published in Biological Psychology. The researchers found that lower reward sensitivity was associated with higher levels of suicidal ideation, regardless of the specific diagnosis. Cognitive-behavioral therapy and supportive therapy were both effective in reducing symptoms of social anxiety and depression, but reward sensitivity remained stable throughout treatment, suggesting it may be a vulnerability marker for suicidal thoughts. Further research is needed to replicate the findings and explore other potential pathways leading to suicidal ideation.

via PsyPost|

#depression #mental-health #psychotherapy

health3 years ago•3 min saved

Personality plays a role in oxytocin's impact on psychiatric symptoms.

The effects of oxytocin on psychiatric symptoms depend on personality characteristics, according to a study of hospitalized patients with severe mental illness in Israel. Oxytocin administration improved symptoms in participants low in openness and extraversion, but led to a deterioration of the working alliance with the therapist in participants low in agreeableness and neuroticism. The study sheds light on the effect of oxytocin on important psychological processes, but also has limitations that need to be taken into account.

via PsyPost|

#health #mental-health #oxytocin

mental-health3 years ago•15 min saved

The Future of Suicidal Depression Treatment.

The Stanford neuromodulation therapy (SNT) protocol, a new approach to transcranial magnetic stimulation (TMS) for treatment-resistant depression, has shown promising results in treating high-acuity psychiatric emergencies. The protocol uses a new form of stimulation called theta-burst stimulation, which compresses the entire FDA-approved theta-burst course from 6 weeks into a single day. The treatment has been shown to be effective in people who failed electroconvulsive therapy and can be personalized to an individual's needs. However, more research is needed to determine the ideal protocol and maintenance treatment for long-term success. The treatment is not yet widely available but may become more accessible in the future.

via Medscape|

#depression #mental-health #neuromodulation