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Suvorexant

All articles tagged with #suvorexant

science2 months ago•6 min saved

Sleep Pill Shows Short-Term Drop in Alzheimer's Proteins in Small Study

A small two-night, placebo-controlled study at a sleep clinic with 38 healthy adults aged 45–65 found that suvorexant reduced cerebrospinal fluid amyloid-beta by 10–20% and temporarily lowered some forms of tau, even though there were no sleep differences between groups. The results suggest a link between promoting sleep and Alzheimer's biomarkers, but researchers caution against using sleeping pills as a preventive strategy without longer, larger trials and acknowledge potential downsides of long-term use.

via ScienceAlert|

#alzheimers-disease #neuroscience #science

health9 months ago•4 min saved

Sleeping Pill May Lower Alzheimer's Protein Levels, Study Shows

A 2023 study suggests that using the sleep aid suvorexant for two nights may reduce levels of Alzheimer's-related proteins in healthy middle-aged adults, highlighting a potential link between sleep improvement and Alzheimer's prevention, though more research is needed before recommending sleep pills for this purpose.

via ScienceAlert|

#alzheimers #brain-health #health

health2 years ago•3 min saved

Insomnia medication reduces Alzheimer's protein levels.

A drug called suvorexant, approved to treat insomnia, has been found to reduce levels of proteins associated with Alzheimer’s disease in cerebrospinal fluid in a small study. Researchers are launching a clinical trial to further test the drug in people at risk of developing dementia. The drug is a dual orexin receptor antagonist (DORA) that blocks orexin, a chemical in the brain that promotes wakefulness. The study results are encouraging, but further research is needed to understand the long-term effects of the drug on cognitive decline.

via National Institutes of Health (.gov)|

#alzheimers-disease #clinical-trial #dementia-prevention

health2 years ago•5 min saved

Insomnia Medication Belsomra Could Combat Opioid Addiction

A preclinical study found that suvorexant (Belsomra), an insomnia drug, could be a potential treatment for opioid use disorder (OUD) in rats. Suvorexant reduced prescription opioid intake and helped protect against relapse in rats modeling OUD. If the results translate to humans in clinical trials, the insomnia drug could offer a promising approach for the millions of people who have OUD. Suvorexant was designed to inhibit the activity of both the orexin-1 and orexin-2 brain-cell receptors, which are also involved in the process of drug dependency.

via Neuroscience News|

#health #insomnia-drug #opioid-addiction

health3 years ago•5 min saved

Sleeping pills may hold promise in reducing Alzheimer's disease proteins.

A recent study published in Annals of Neurology found that taking the sleep medication suvorexant before bed reduced the levels of Alzheimer's proteins in the spinal fluid of participants. Alzheimer's patients often experience sleep disturbances, but it's unclear whether poor sleep causes Alzheimer's or vice versa. The study included 38 participants who had no known cognitive impairments and no evidence of Alzheimer's-related changes in the brain. While the initial results are promising, longer-term studies with larger participant groups are needed to confirm the findings. The study author recommends that individuals with sleep disturbances should see their doctor and be evaluated for sleep disorders before taking any medications.

via Fox News|

#alzheimers-disease #brain-proteins #health

health3 years ago•2 min saved

Sleeping pill shows promise in reducing Alzheimer's proteins.

Researchers at Washington University School of Medicine in St. Louis have found that the FDA-approved insomnia pill suvorexant, also known as Belsomra, can reduce harmful proteins associated with Alzheimer's disease. The study was conducted over a two-night span and showed "proof-of-concept" that the drug affects the levels of proteins critical for driving Alzheimer's disease. Although more research is needed, the results are encouraging and suggest that daily reductions of the proteins could bolster long-term neurological health. However, long-term usage of sleeping pills, particularly in older adults, can have dangers.

via New York Post |

#alzheimers-disease #cognitive-decline #health

health3 years ago•5 min saved

Sleeping Pill Reduces Alzheimer's Proteins, Study Shows

A small study suggests that the insomnia medication suvorexant could potentially reduce Alzheimer’s proteins in the brain, but more research is needed to confirm its effectiveness in preventing or slowing the disease. Participants who took a higher dose of the drug experienced a significant drop in amyloid and hyperphosphorylated tau levels. Sleep disturbances can be an early sign of Alzheimer’s disease, and poor sleep accelerates harmful changes to the brain.

via SciTechDaily|

#alzheimers-disease #amyloid #health

health3 years ago•2 min saved

Sleep medication may reduce Alzheimer's pathology.

A preliminary study conducted by researchers at the Washington University School of Medicine in St. Louis has revealed that taking a particular sleeping pill known as suvorexant before bed may help reduce the levels of Alzheimer's disease proteins. The study was designed to determine if suvorexant could reduce amyloid and tau protein levels, which are associated with Alzheimer's disease. However, experts caution that it is too early to determine if the medication is effective in staving off cognitive decline.

via The News International|

#alzheimers-disease #amyloid-plaques #cognitive-decline

neuroscience3 years ago•6 min saved

Sleeping Pills Could Halt Alzheimer's Progression, Study Suggests

A small study has shown that suvorexant, a sleep medication commonly prescribed to treat insomnia, reduced levels of the Alzheimer’s-associated amyloid beta protein and hyperphosphorylated tau protein in the brain. The study suggests that sleep medications could slow or stop the progression of Alzheimer’s disease, but more research is needed to confirm the viability of such an approach.

via Neuroscience News|

#alzheimers-disease #amyloid-beta-protein #neuroscience

health3 years ago•2 min saved

Sleeping Pills May Prevent Alzheimer's, Study Shows.

A small proof-of-concept study by researchers at Washington University School of Medicine in St. Louis found that a sleeping pill used to treat insomnia, suvorexant, lowered Alzheimer's-associated waste proteins, beta-amyloid and tau proteins, suggesting future preventative care for the disease focused on preserving and restoring good sleep. The study monitored 38 middle-aged participants for two nights in a sleep lab and found that participants who received the higher dose of suvorexant and got a good night’s sleep had 10-20 percent lower levels of beta-amyloid than participants who didn’t receive the medication.

via The Daily Beast|

#alzheimers-disease #beta-amyloid #health

health3 years ago•4 min saved

"Sleeping Pill and Bedtime Trick Show Promise in Reducing Alzheimer's Risk"

A small study conducted by researchers at the University of Washington in St Louis, Missouri, found that a common sleeping pill, suvorexant, can reduce the levels of Alzheimer's linked proteins in the brain. Participants who took the highest dose had amyloid levels that were up to a fifth lower than other participants in their spinal fluid by the next morning. However, scientists are not urging people to start taking the pills every night, saying much more extensive research is needed to back up the results.

via Daily Mail|

#alzheimers #amyloid #health