All articles tagged with #biobanks
A DNA-virome analysis of blood and saliva from biobanks shows Epstein–Barr virus DNA abundance varies with age, sex, and dozens of genetic variants, and genetic analyses indicate high latent EBV is a causal risk factor for Hodgkin’s lymphoma.
Researchers show that non-human DNA discarded during whole-genome sequencing can be repurposed to detect and quantify Epstein–Barr virus DNA in human cells, using a method described by Nyeo et al. in Nature. This population-scale approach lets biobanks reveal persistent EBV DNA and its links to complex diseases, turning sequencing byproducts into a new source of epidemiological insight.
Researchers are increasingly leveraging biobanks, large collections of biological samples and data, to enhance scientific studies. The article highlights how biobanks like the UK Biobank facilitate access to extensive, diverse datasets, enabling breakthroughs in health research, despite challenges related to costs, legalities, and underutilization. The growth of biobanking, driven by technological advances, is transforming research capabilities across the globe.
China is investing heavily in its efforts to become a global leader in the biosciences by collecting and asserting more oversight over its vast genetic data resources. The government has launched a "national genetic survey" to centralize and standardize existing data, while also tightening controls on foreign access. However, experts warn that this genetic hoarding could hinder international research collaboration and backfire on China's own aspirations. The country's fragmented biobanking system and scattered databases pose challenges, and the new regulations aim to address these issues. China's strict approach to genetic material is driven by concerns over illegal outflow and a desire for "genomic sovereignty," but it risks hindering scientific advancement and collaboration.
Biobanks, repositories that store genetic data and other biospecimens, are increasingly being used for research purposes. However, concerns have been raised about the informed consent process and the potential misuse of genetic data. A recent study found that even when participants choose not to respond to survey questions, their genetic data can reveal information about their education, health, and income levels. While genetic data is de-identified and used at the aggregate level, there is a need for improved transparency and understanding of how biobanks use participants' data to ensure informed consent and protect privacy.