Tag

Biomaterials

All articles tagged with #biomaterials

Narwhal Tusks Unveil Twin Spiral Structure Through 3D X-Rays
science2 days ago

Narwhal Tusks Unveil Twin Spiral Structure Through 3D X-Rays

Researchers using advanced 3D X-ray imaging from multiple synchrotrons revealed that the narwhal’s tusk is a double spiral: the outer cementum twists left, the inner dentin twists right, forming a biological counterbalance that enhances strength. The tusk, which is the narwhal’s left canine and can exceed two meters, grows through the jaw and lip and is commonly seen as a sexual signal, though its exact function remains debated. The findings, published in Nature, also suggest the growth pattern is genetically programmed and that the tusk could serve as a record of environmental change over the animal’s roughly 80-year lifespan, potentially inspiring new materials design.

Spider Silk Inspires Next-Gen Medical Materials for Drug Delivery and Wound Repair
science21 days ago

Spider Silk Inspires Next-Gen Medical Materials for Drug Delivery and Wound Repair

Spider silk is guiding the development of new medical materials. Researchers extract silk genes and produce engineered silk proteins in microbes to create particles, gels, fibers, and 3D-printed scaffolds for drug delivery and tissue repair. These silk-based systems can biodegrade and release medicines over time, while providing biocompatible scaffolds that support cell growth and healing, with applications ranging from wound coverings to bone regeneration. The process leverages room‑temperature, water-based manufacturing that contrasts with traditional synthetic fibers.

Ancient bristle worm jaws redefine metal in biology as a new class of bio-metals
discoveries1 month ago

Ancient bristle worm jaws redefine metal in biology as a new class of bio-metals

Microscopic tests of Perinereis cultrifera jaws show ion‑coordinated proteins that harden toward the tips and display metal‑like, size‑dependent elasticity, supporting a new category called bio-metals that blend polymeric structure with metal‑like hardness; researchers used nanoindentation and manifold micromechanics to define bio-metals by hardness, strain behavior, and ion‑protein structure and plan to study more species and potential genetic links to material design.

Bees’ Silk Breakthrough: Lab‑Produced Bee Silk unlocks new biomaterial avenues
science1 month ago

Bees’ Silk Breakthrough: Lab‑Produced Bee Silk unlocks new biomaterial avenues

Scientists have developed a non-invasive lab method to produce solitary-bee silk by raising larvae in a 3D-printed nest, extracting silk fibers from the larva’s mouth, and using engineered microbes to output silk proteins (fibroins) that are cast into films. This first demonstration with Osmia lignaria cocoons the silk’s protective, breathable properties in a lab-friendly material, with potential biomedical applications (sutures, scaffolds) and possibilities for blending bee silk with hagfish slime to enhance performance.

Split-second slime: hagfish defense clogs predators' gills
science1 month ago

Split-second slime: hagfish defense clogs predators' gills

When pressed by a predator, hagfish release two cargoes of proteins and mucus into seawater, where they rapidly unravel into a fibrous slime that clogs a predator’s gills in a fraction of a second, often causing the attacker to back off. A full slime-out can reach about a liter from a small amount of exudate; the defense is triggered by direct contact rather than sight. Hagfish can shed slime and clean themselves by knotting and sneezing, and researchers study this fast, water-based slime as inspiration for new materials.

Darwin’s Bark Spider Spins Ultra-Tough Silk and Bridges Rivers Across Madagascar
science2 months ago

Darwin’s Bark Spider Spins Ultra-Tough Silk and Bridges Rivers Across Madagascar

A Madagascan spider, Darwin’s bark spider (Caerostris darwini), weaves dragline silk that is the toughest biological material measured to date, absorbing more energy than Kevlar by roughly tenfold; its webs span rivers with bridge lines up to 25 meters. The toughness arises from a mix of solid strength and unusually high elasticity, and researchers note the silk isn’t yet mass-producible due to the impossibility of farming spiders. The work also highlights bioprospecting as a targeted approach to discovering extraordinary natural materials.

NIH funds UCLA biomaterials breakthroughs for eye repair and wound healing
science2 months ago

NIH funds UCLA biomaterials breakthroughs for eye repair and wound healing

UCLA chemical engineering associate professor Nasim Annabi has secured nearly $2.5 million in NIH grants to develop tunable regenerative biomaterials: a four-year, light-curable hydrogel that encapsulates mesenchymal stem cells to treat corneal injuries, and a two-year, roughly $368,000 award to improve UgiGel, a gelatin-based self-healing bioadhesive dressing with anti-inflammatory properties for chronic wound healing. The corneal project aims to enhance cell retention and tissue regeneration with two hydrogel variants (softer adhesive for epithelium growth and stronger adhesive for tissue repair), while the wound-dressing work seeks stronger adhesion, antioxidant improvements, and temperature-responsive removal, in collaboration with dermatology and medicine researchers at UCLA.

Regenerative OA Therapies Rebuild Joints in Weeks, Near Clinical Trials
health2 months ago

Regenerative OA Therapies Rebuild Joints in Weeks, Near Clinical Trials

In animal studies, two regenerative approaches—a single injectable that releases medication over months and a biomaterial scaffold that recruits body’s progenitor cells—repaired damaged cartilage and bone within 4–8 weeks, with ARPA-H funding advancing the project toward clinical trials in about 18 months, aiming for affordable, minimally invasive, single-visit therapies that could eventually reduce the need for joint replacement.

Hagfish Slime Sparks a Sustainable Materials Revolution
science6 months ago

Hagfish Slime Sparks a Sustainable Materials Revolution

Hagfish slime rapidly expands into a dense gel when seawater is present, using ultra-thin protein threads that self-assemble into a fibrous network and can clog predators’ gills in seconds. Produced at room temperature in seawater with no toxic byproducts, this slime is inspiring researchers to develop sustainable biomaterials—self-assembling fibers that could rival spider silk. Scientists aim to isolate the slime proteins’ genes for production in microbes, but scaling, control of assembly, and durability remain key hurdles.

Innovative Heart Patch Promises Improved Recovery Post-Heart Attack
health9 months ago

Innovative Heart Patch Promises Improved Recovery Post-Heart Attack

MIT engineers have developed a flexible, programmable drug-delivery patch that can be applied to the heart after a heart attack to promote tissue healing and regeneration, showing promising results in rat studies by reducing damaged tissue and improving heart function. If approved for humans, it could significantly enhance recovery outcomes for heart attack patients.