Tag

Bioengineering

All articles tagged with #bioengineering

Lab-made SpudCell: lifelike but not autonomous
science3 days ago

Lab-made SpudCell: lifelike but not autonomous

Scientists report SpudCell, a bottom‑up synthetic cell built from 36 purified enzymes and a fatty membrane with a minimal genome, which can feed, grow, and divide in a dish. However, it cannot produce its own energy, lacks full ribosomal machinery, and relies on externally supplied fats, sugars, and enzymes; its genome is distributed on plasmids and cell division can be imperfect. Described as a proof‑of‑principle rather than a living, autonomous organism, the work could someday enable new on‑demand chemical or pharmaceutical production, but peer review is pending and some scientists urge caution about hype and autonomy claims.

SpudCell: first synthetic cell built from non-living components completes a full life cycle
science9 days ago

SpudCell: first synthetic cell built from non-living components completes a full life cycle

Scientists report creating SpudCell, the first synthetic cell assembled from non-living components that can grow, divide, and complete a life cycle using a 90-kilobase genome; while not yet peer‑reviewed and not truly self-sustaining or evolvable, the work provides a programmable chassis for future bioengineering and explorations of what defines life.

The Pacemaker Patch: An External Ultrasound Approach to Pacing the Heart
technology27 days ago

The Pacemaker Patch: An External Ultrasound Approach to Pacing the Heart

Researchers envision a chest-mounted patch that uses high-frequency ultrasound to pace the heart, made possible by a gene-therapy step that makes heart cells produce a sound-sensitive protein; the system would pair with a pocket-sized data/power module and has shown responses in rats, pigs, and human heart cells. While intriguing as a potential alternative to implanted pacemakers, it remains experimental, with safety, regulatory, and practicality questions to resolve before clinical use.

Spinach-Inspired Photosynthesis Targets Dry Eye in Eye Cells
science1 month ago

Spinach-Inspired Photosynthesis Targets Dry Eye in Eye Cells

Scientists at NUS bioengineered spinach-derived photosynthetic machinery to function in mammalian corneal cells via eye drops, using light to generate anti-inflammatory chemicals and combat oxidative stress in dry eye disease, a condition affecting about 1.5 billion people; the work, published in Cell, explores a novel, plant-based approach to treating dry eye by harnessing light-driven chemistry in eye tissues (still at early model stages).

Living plastic with a built-in kill switch can self-destruct on command
technology2 months ago

Living plastic with a built-in kill switch can self-destruct on command

Chinese researchers embedded dormant Bacillus subtilis spores in polycaprolactone to create a 'living plastic' with a built-in kill switch. When exposed to warm nutrient broth (~50°C), the spores activate and two enzyme-producing strains—Candida antarctica lipase and Burkholderia cepacia lipase—cooperate to cut long polymer chains and then digest the fragments, fully degrading the film in about six days without leaving microplastics. A wearable electrode prototype showed the material could form recoverable electronics before dissolving; however, the approach uses a relatively easy-to-degrade polymer and requires a lab-like trigger, limiting practicality for real-world plastics or consumer use.

Neurobots: Self-Assembling Frog-Cell Machines Grow Functional Nerves
science2 months ago

Neurobots: Self-Assembling Frog-Cell Machines Grow Functional Nerves

Tufts and Wyss Institute researchers embedded neural precursor cells into self-assembling frog-cell xenobots to create neurobots with functional neural networks that move more complexly and stay active longer than non-neural bots; drug testing showed neural activity shapes movement, and transcriptomics revealed upregulation of vision-related genes, opening questions about nervous system formation in a novel biological context.

Hagfish Slime Sparks a Sustainable Materials Revolution
science4 months ago

Hagfish Slime Sparks a Sustainable Materials Revolution

Hagfish slime rapidly expands into a dense gel when seawater is present, using ultra-thin protein threads that self-assemble into a fibrous network and can clog predators’ gills in seconds. Produced at room temperature in seawater with no toxic byproducts, this slime is inspiring researchers to develop sustainable biomaterials—self-assembling fibers that could rival spider silk. Scientists aim to isolate the slime proteins’ genes for production in microbes, but scaling, control of assembly, and durability remain key hurdles.

Small Machines, Big Inside Cells: 3D-Printed Devices Take Shape Within Living Cells
technology5 months ago

Small Machines, Big Inside Cells: 3D-Printed Devices Take Shape Within Living Cells

Researchers have 3D-printed microstructures inside living cells using two-photon polymerization by injecting a light-sensitive resin and curing it with a femtosecond laser; the resulting structures, including a 10 μm Elephant-like model, float in the cytoplasm and can be inherited when cells divide. Viability after 24 hours is about 55% for printed cells, with most losses due to membrane damage from the injection rather than the printing itself. Demonstrations include barcodes, diffraction gratings, and microlasers, signaling potential for intracellular tagging and sensing, while challenges in viability and integration remain.

Scientists Address Doomsday Threats of 'Mirror Life'
science9 months ago

Scientists Address Doomsday Threats of 'Mirror Life'

Scientists worldwide are discussing the potential risks and benefits of creating mirror life, synthetic cells made from molecules that are mirror images of natural ones, due to concerns about environmental and health dangers versus potential medical and scientific benefits. The conference in Manchester aims to establish guidelines for safe research in this emerging field.