Tag

Endocrine Society

All articles tagged with #endocrine society

health14 days ago•4 min saved

GLP-1 Non-Responders: Scientists Probe Hormonal and Genetic Drivers of Variable Weight Loss

While GLP-1 medications like semaglutide and tirzepatide help many patients lose significant weight, 10–15% of users experience minimal or no results. Researchers are investigating why this occurs, with early evidence pointing to biological sex, oestrogen levels, and genetic factors as key drivers of individual response. The Endocrine Society has designated understanding this heterogeneity as a priority to enable personalized treatments.

via Nature|

#endocrine-society #glp-1-drugs #health

health2 months ago•3 min saved

Vitamin D Guidelines: Test Selectively and Favor Targeted Supplementation

Vitamin D functions as a system-wide hormone important for bone, immunity, and cardiometabolic health, best viewed through three domains: secure substrate (sun, diet, supplements), proper activation (hepatic/renal hydroxylation and FGF23-PTH regulation), and tissue responsiveness. The 2024 Endocrine Society guideline advises against routine 25(OH)D screening in healthy people and limits testing to specific medical indications. It supports empiric supplementation for adults aged 75+ due to potential mortality benefits but does not endorse universal supplementation above dietary references for younger adults to prevent chronic disease, and finds no strong extraskeletal prevention evidence. For those over 50 with an indication, daily low-dose vitamin D is preferred over high-dose boluses, which can be ineffective or harmful. The USPSTF similarly finds no meaningful reduction in fractures or falls in generally healthy older adults. There is modest evidence that vitamin D may reduce progression to diabetes in high-risk prediabetes when added to lifestyle changes, but not as a general preventive measure in euglycemic individuals. The guideline underlines treating documented deficiency and preventing nutritional rickets in children.

via Medscape|

#endocrine-society #guidelines #health

health4 months ago•6 min saved

PMOS: A new name for PCOS to improve diagnosis and care

PMOS—polyendocrine metabolic ovarian syndrome—replaces PCOS to better reflect its metabolic and endocrine nature and reduce misdiagnosis; the rename, published in The Lancet after 14 years of work, aims to improve care. PMOS features irregular periods and excess androgens, can cause acne or hair changes, and is linked to infertility and metabolic risks; treatment focuses on lifestyle changes (diet, exercise, sleep) and personalized options like Metformin, anti-androgens, or hormonal birth control. The change seeks to raise awareness and better tailor care for patients.

via Click2Houston|

#endocrine-society #health #infertility

health2 years ago•4 min saved

New 2024 Guidelines on Vitamin D: Who Needs It and How Much

The Endocrine Society has released new guidelines on vitamin D supplementation, recommending against routine screening for deficiency in most people and suggesting specific intake levels for different age groups and conditions. Children, teens, adults over 70, pregnant women, and those with pre-diabetes may benefit from higher vitamin D intake. The guidelines emphasize the importance of consulting healthcare providers to ensure appropriate vitamin D levels, as excessive intake can be harmful.

via EatingWell|

#endocrine-society #health #health-guidelines

health2 years ago•5 min saved

"New Guidelines Clarify Vitamin D Intake for Adults"

The Endocrine Society's new guidelines advise against routine vitamin D testing in healthy individuals and recommend limiting supplementation to specific risk groups, such as children, pregnant people, adults over 75, and those with prediabetes. The guidelines emphasize adhering to the National Academy of Medicine's recommended daily intakes and highlight the need for more large-scale clinical trials to determine optimal vitamin D levels and intake.

via Medscape|

#endocrine-society #guidelines #health

health2 years ago•5 min saved

New Guidelines Clarify Vitamin D Intake for Adults

The Endocrine Society's new Clinical Practice Guideline advises against excessive vitamin D supplementation and unnecessary testing in healthy adults under 75. It recommends higher vitamin D intake for children, the elderly over 75, pregnant individuals, and adults with prediabetes. The guideline, based on clinical trials, aims to address vitamin D requirements for disease prevention in generally healthy populations.

via SciTechDaily|

#endocrine-society #guidelines #health

healthcare-technology3 years ago•3 min saved

"Combatting CGM Alarm Fatigue in Youth: Strategies and Solutions"

Continuous glucose monitors (CGMs) with alarm settings that generate too many alerts may lead to alarm fatigue in teenagers with diabetes, causing them to ignore the devices, according to a study presented at the 2023 annual meeting of the Endocrine Society. The study analyzed two weeks of real-time CGM alarm settings from 150 children with diabetes treated at Indiana, and found that alarm settings often varied widely from thresholds recommended by the University of Colorado’s Barbara Davis Center for Diabetes. Experts advise parents and children to be thoughtful about setting their CGM alarm thresholds to be most useful to them.

via Medscape|

#alarm-settings #cgm #diabetes

health3 years ago•4 min saved

Streamlining Hormone Treatment for Aging with New Guidance

The Endocrine Society has released a statement on hormones and aging, covering nine parts or axes, including growth hormone, adrenal, ovarian, testicular, thyroid, osteoporosis, vitamin D deficiency, type 2 diabetes, and water metabolism. The statement aims to clarify misunderstandings and provide a concise summary of available therapies, clinical trial data, key points, and research gaps. It tackles controversial areas such as hormone replacement therapy, diabetes treatment goals, and vitamin D supplementation in older adults. The document is a one-stop-shop for clinicians to learn about hormonal changes in aging and when treatment is and isn't appropriate.

via Medscape|

#aging #endocrine-society #health

healthcare3 years ago•2 min saved

AMA Takes Stronger Position on Gender-Affirming Care

The American Medical Association (AMA) has passed a resolution at its annual meeting to protect gender-affirming care, opposing legal penalties for patients and their families accessing such care, protecting doctors from legal and physical threats, and advocating against legislation that limits gender-affirming care. The AMA has publicly supported gender-affirming medicine for years and has also shown support for intersex people. The resolution was introduced by the Endocrine Society and passed with limited opposition. The AMA also passed resolutions opposing mandated reporting of LGBTQ+ identities and de-emphasizing the use of BMI in assessing patient health.

via Them|

#american-medical-association #endocrine-society #gender-affirming-care