Tag

Epigenetic Clocks

All articles tagged with #epigenetic clocks

science2 months ago•5 min saved

Wealth, Racism and the Pace of Aging Revealed by Epigenetic Clocks

A cross‑country study of 66,000 people finds that lower socioeconomic status and racial marginalization are tied to faster biological aging, as measured by newer epigenetic clocks that track health and mortality risk; the strongest effects appear with the latest clocks, and children in poorer conditions also show accelerated aging, highlighting how poverty and discrimination shape aging and could guide targeted health interventions—though pediatric clock estimates are less certain due to developmental factors.

via ScienceAlert|

#aging #epigenetic-clocks #health-disparities

health2 months ago•13 min saved

Semaglutide Shows 3–5 Year Slowdown in Biological Aging in a 2025 Trial

In a 32-week, randomized trial of 108 adults with HIV-associated lipohypertrophy, weekly semaglutide reduced biological age by about 3.1 years on multiple epigenetic clocks and up to 5 years on the most sensitive ones, with DunedinPACE slowing by ~9%. The biomarker shifts correlated with reductions in inflammation and visceral fat, suggesting aging slows via metabolic effects rather than a direct anti-aging action. Limitations include population specificity and reliance on epigenetic biomarkers; broader trials are needed to determine applicability to the general population and real-world health outcomes.

via Space Daily|

#aging #epigenetic-clocks #glp-1-receptor-agonists

science2 months ago•5 min saved

GLP-1 Weight-Loss Drug Slows Biological Aging Markers in HIV Patients, Study Finds

In a randomized trial of 108 adults with HIV-associated lipohypertrophy, semaglutide slowed several epigenetic aging clocks—9% on DunedinPACE and reduced PCGrimAge–related aging risk—suggesting GLP-1 drugs may influence aging biology beyond weight loss, though larger studies are needed.

via SciTechDaily|

#aging #epigenetic-clocks #glp-1

science3 months ago•5 min saved

Consistent daily routines linked to slower aging markers, study finds

A Johns Hopkins-led study analyzing 207 older adults found that stable rest-activity/sleep patterns correlate with slower biological aging as measured by four epigenetic clocks, though the snapshot design means causality isn’t established and longitudinal data are needed.

via ScienceAlert|

#aging #circadian-rhythms #daily-routine

health3 months ago•5 min saved

Artful aging: regular arts engagement may slow biological clocks

A UK study of more than 3,500 adults found that engaging in weekly arts or cultural activities (visiting museums, crafting, singing, etc.) is linked to slower biological aging across several epigenetic clocks. The DunedinPACE clock showed up to 4% slower aging for those with weekly activity, and PhenoAge suggested about a one-year younger biological age, with stronger effects in middle-aged adults, indicating arts participation may promote health similarly to regular exercise.

via ScienceAlert|

#aging #arts-engagement #dunedinpace

health3 months ago•5 min saved

Daily arts and culture linked to slower biological aging, study finds

A UK study of 3,556 adults links regular participation in arts and cultural activities to a slower pace of biological ageing, with weekly engagement associated with about 4% slower ageing—comparable to regular exercise—particularly among those aged 40 and over, as measured by several epigenetic clocks.

via Euronews.com|

#aging #arts-engagement #biological-ageing

science3 months ago•11 min saved

Epigenetic clocks are research tools, not consumer health tests

Epigenetic aging clocks sold as “biological age” tests are powerful research tools for studying aging at the population level but unreliable for individuals: dozens of clocks can disagree, results vary by sample type and short-term factors, and there is no universal gold standard. They are not medical diagnostics and should be used by researchers to identify population-level lifestyle factors that slow aging or to test therapies, not for personal health decisions or insurance decisions, though future work may eventually inform individualized care.

via The Conversation|

#aging #biological-age #dna-methylation

science4 months ago•3 min saved

Tiny Edge Against Aging Markers Found in Daily Multivitamins, Study Says

In a 2-year randomized trial of 958 older adults (average age ~70), daily multivitamin–multimineral supplements modestly slowed increases in two DNA-based aging clocks (PCPhenoAge by ~2.6 months, PCGrimAge by ~1.4 months); cocoa extract had no effect. The benefit was larger for those with faster baseline aging. Limitations include a largely homogeneous sample and the small magnitude of effect; epigenetic clocks are preliminary biomarkers, so more diverse, longer studies are needed to determine if these changes affect health or lifespan.

via SciTechDaily|

#aging #clinical-trial #epigenetic-clocks

health5 months ago•5 min saved

Daily Multivitamin Linked to Slower Biological Aging in Seniors

A two-year, randomized analysis of 958 older adults found that daily multivitamin use slowed biological aging by about four months across five epigenetic clocks, with greater benefit for those who were biologically older at baseline. The study, part of the COSMOS trial and funded in part by Mars Edge and Haleon, does not prove a longer lifespan and experts caution that more research is needed. Diet quality and a balanced diet may be more impactful in general, and multivitamins can be costly or give a false sense of security. FDA regulation concerns and potential nutrient overdosage were noted, with a recommendation to prioritize real food for most people.

via Prevention|

#aging #cosmos-study #epigenetic-clocks

health5 months ago•7 min saved

Daily multivitamins linked to slower cellular aging in seniors

A two-year randomized trial of nearly 1,000 healthy older adults (average age ~70) found that daily multivitamin-mineral supplements slowed cellular aging by about four months, as measured by five epigenetic clock biomarkers. The effect was modest, and researchers caution that it’s not yet clear how this translates to real health outcomes; further studies are planned to assess clinical benefits.

via Fox News|

#aging #biomarkers #epigenetic-clocks

health5 months ago•42 min saved

Daily Multivitamin May Slow Aging by a Few Months in Older Adults

A Nature Medicine-backed study of 958 adults aged 60+ over 2 years found that daily multivitamin–multimineral supplementation modestly slowed biological aging by up to about 4 months, as measured by five epigenetic clocks; cocoa extract had no effect; the benefit was larger for participants with accelerated aging at baseline. Researchers emphasize these changes are biomarkers, not proven lifespan or disease reductions, and lifestyle factors remain key to healthy aging—vitamins should complement, not replace, a nutrient-rich diet.

via Healthline|

#aging #biological-aging #epigenetic-clocks

health5 months ago•6 min saved

Daily Multivitamin Slows Biological Aging Clock by Four Months in Seniors

A large two-year randomized trial found that older adults taking a daily multivitamin slowed their biological aging clocks (GrimAge and PhenoAge) by about four months vs. placebo. The effect is small and its health implications are not yet clear, suggesting nutrients may help those with dietary gaps, but more research is needed before altering supplement habits.

via Business Insider|

#aging #epigenetic-clocks #health

science5 months ago•5 min saved

Regular Multivitamin Use May Slow Biological Aging, COSMOS Study Finds

A two-year daily multivitamin in the COSMOS study slowed aging markers on two epigenetic clocks in about 1,000 older adults, while cocoa flavanol supplementation showed no effect. The multivitamin also correlated with improvements in inflammation and cognitive function, but researchers caution that larger trials are needed to confirm clinical benefits and longevity impact.

via ScienceAlert|

#aging #cosmos-study #epigenetic-clocks

health5 months ago•1 min saved

Daily multivitamins linked to slower biological aging in seniors, study finds

A Nature Medicine study of 958 older adults (average age 70) found that taking a daily Centrum Silver multivitamin–mineral for two years slowed biological aging by about four months across five epigenetic clocks; cocoa extract had no effect. Researchers caution that these early biomarker findings have not yet shown impacts on clinical outcomes and do not prove reduced disease risk.

via USA Today|

#aging #clinical-research #epigenetic-clocks

health5 months ago•6 min saved

Multivitamin use slows aging clock in seniors, study suggests

In a two-year randomized trial of 958 healthy older adults, daily multivitamins slowed biological aging by about four months (aging 20 months biologically over 24 months) as measured by epigenetic clocks, with greater benefit for those who started with accelerated aging. Cocoa extract had no effect. The researchers caution the findings don’t imply lifespan extension and results may not generalize beyond a mostly white, healthy population.

via NBC News|

#aging #cosmos-study #epigenetic-clocks