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Epigenetic Clocks

All articles tagged with #epigenetic clocks

Tiny Edge Against Aging Markers Found in Daily Multivitamins, Study Says
science11 days ago

Tiny Edge Against Aging Markers Found in Daily Multivitamins, Study Says

In a 2-year randomized trial of 958 older adults (average age ~70), daily multivitamin–multimineral supplements modestly slowed increases in two DNA-based aging clocks (PCPhenoAge by ~2.6 months, PCGrimAge by ~1.4 months); cocoa extract had no effect. The benefit was larger for those with faster baseline aging. Limitations include a largely homogeneous sample and the small magnitude of effect; epigenetic clocks are preliminary biomarkers, so more diverse, longer studies are needed to determine if these changes affect health or lifespan.

via SciTechDaily|
#aging#clinical-trial#epigenetic-clocks
Daily Multivitamin Linked to Slower Biological Aging in Seniors
health28 days ago

Daily Multivitamin Linked to Slower Biological Aging in Seniors

A two-year, randomized analysis of 958 older adults found that daily multivitamin use slowed biological aging by about four months across five epigenetic clocks, with greater benefit for those who were biologically older at baseline. The study, part of the COSMOS trial and funded in part by Mars Edge and Haleon, does not prove a longer lifespan and experts caution that more research is needed. Diet quality and a balanced diet may be more impactful in general, and multivitamins can be costly or give a false sense of security. FDA regulation concerns and potential nutrient overdosage were noted, with a recommendation to prioritize real food for most people.

via Prevention|
#aging#cosmos-study#epigenetic-clocks
Daily multivitamins linked to slower cellular aging in seniors
health29 days ago

Daily multivitamins linked to slower cellular aging in seniors

A two-year randomized trial of nearly 1,000 healthy older adults (average age ~70) found that daily multivitamin-mineral supplements slowed cellular aging by about four months, as measured by five epigenetic clock biomarkers. The effect was modest, and researchers caution that it’s not yet clear how this translates to real health outcomes; further studies are planned to assess clinical benefits.

via Fox News|
#aging#biomarkers#epigenetic-clocks
Daily Multivitamin May Slow Aging by a Few Months in Older Adults
health29 days ago

Daily Multivitamin May Slow Aging by a Few Months in Older Adults

A Nature Medicine-backed study of 958 adults aged 60+ over 2 years found that daily multivitamin–multimineral supplementation modestly slowed biological aging by up to about 4 months, as measured by five epigenetic clocks; cocoa extract had no effect; the benefit was larger for participants with accelerated aging at baseline. Researchers emphasize these changes are biomarkers, not proven lifespan or disease reductions, and lifestyle factors remain key to healthy aging—vitamins should complement, not replace, a nutrient-rich diet.

via Healthline|
#aging#biological-aging#epigenetic-clocks
Daily Multivitamin Slows Biological Aging Clock by Four Months in Seniors
health1 month ago

Daily Multivitamin Slows Biological Aging Clock by Four Months in Seniors

A large two-year randomized trial found that older adults taking a daily multivitamin slowed their biological aging clocks (GrimAge and PhenoAge) by about four months vs. placebo. The effect is small and its health implications are not yet clear, suggesting nutrients may help those with dietary gaps, but more research is needed before altering supplement habits.

via Business Insider|
#aging#epigenetic-clocks#health
Regular Multivitamin Use May Slow Biological Aging, COSMOS Study Finds
science1 month ago

Regular Multivitamin Use May Slow Biological Aging, COSMOS Study Finds

A two-year daily multivitamin in the COSMOS study slowed aging markers on two epigenetic clocks in about 1,000 older adults, while cocoa flavanol supplementation showed no effect. The multivitamin also correlated with improvements in inflammation and cognitive function, but researchers caution that larger trials are needed to confirm clinical benefits and longevity impact.

via ScienceAlert|
#aging#cosmos-study#epigenetic-clocks
Daily multivitamins linked to slower biological aging in seniors, study finds
health1 month ago

Daily multivitamins linked to slower biological aging in seniors, study finds

A Nature Medicine study of 958 older adults (average age 70) found that taking a daily Centrum Silver multivitamin–mineral for two years slowed biological aging by about four months across five epigenetic clocks; cocoa extract had no effect. Researchers caution that these early biomarker findings have not yet shown impacts on clinical outcomes and do not prove reduced disease risk.

via USA Today|
#aging#clinical-research#epigenetic-clocks
Multivitamin use slows aging clock in seniors, study suggests
health1 month ago

Multivitamin use slows aging clock in seniors, study suggests

In a two-year randomized trial of 958 healthy older adults, daily multivitamins slowed biological aging by about four months (aging 20 months biologically over 24 months) as measured by epigenetic clocks, with greater benefit for those who started with accelerated aging. Cocoa extract had no effect. The researchers caution the findings don’t imply lifespan extension and results may not generalize beyond a mostly white, healthy population.

via NBC News|
#aging#cosmos-study#epigenetic-clocks
Some PFAS Chemicals May Speed Up Biological Aging in Middle-Aged Men, Study Finds
science1 month ago

Some PFAS Chemicals May Speed Up Biological Aging in Middle-Aged Men, Study Finds

A Shanghai Jiao Tong University–led study using US NHANES data links higher blood levels of PFNA and PFOSA to faster epigenetic aging in men aged 50–64, with no similar effect in women; while it shows association, not causation, the findings suggest some newer PFAS alternatives may pose aging risks and underscore the need to limit exposure and study chemical mixtures.

via ScienceAlert|
#aging#epigenetic-clocks#pfas
Astronauts Age Rapidly in Space, Then Rejuvenate on Earth
science2 months ago

Astronauts Age Rapidly in Space, Then Rejuvenate on Earth

A small study of four astronauts on the Axiom-2 mission found rapid changes in aging biomarkers during a few days in microgravity, tracked via epigenetic clocks; after returning to Earth, those markers reversed, even dropping below preflight levels for some. The results imply space stress can accelerate aging in real time and that the body may have intrinsic rejuvenation mechanisms, though the study has limitations including a small sample and no ground control.

via The Daily Galaxy|
#aging#astronauts#epigenetic-clocks