All articles tagged with #fibromyalgia
TMZ reports Lady Gaga welcomed her daughter Rose Bean Polansky via surrogate in Los Angeles on June 9, 2026. Gaga, who has fibromyalgia, has long teased motherhood as her next big chapter, and she shares this moment with partner Michael Polansky.
A multi-ancestry GWAS meta-analysis of 2.56 million individuals (54,629 cases; 2,509,126 controls) identified 26 fibromyalgia risk loci, led by a coding HTT variant; neural genes such as DCC, DRD2/NCAM1, MDGA2 and CELF4 highlight brain pathways as central to fibromyalgia. Heritability is enriched in brain tissues and neurons, with dentate gyrus neurons showing the strongest signal, supporting a CNS basis and possible gut–brain interactions via enteric neurons. Genetic correlations show widespread pleiotropy with chronic pain, psychiatric and metabolic traits, notably pain syndromes and PTSD. The genetic architecture is nearly identical in males and females, despite prevalence differences. Polygenic risk scores have modest predictive value (highest AUC ~0.59 in Europeans) and can stratify risk. Therapeutic implications include HTT/GPR52 and CELF4 targets, arguing against a primary autoimmune etiology. Limitations include predominantly European ancestry and ICD-based phenotyping; replication in diverse groups is needed. Overall, findings map fibromyalgia to central nervous system biology and provide molecular entry points for future research.
A real-world trial across 28 clinics found that adding transcutaneous electrical nerve stimulation (TENS) to standard physical therapy significantly reduced movement-evoked pain and fatigue in fibromyalgia patients, with a dose-dependent effect lasting at least six months. About 80% of participants found TENS helpful and 70% felt better overall, and the benefits did not fade over time, making TENS a safe, inexpensive adjunct to PT and medications rather than a standalone cure.
A U.S. circuit court ruled that in cases like fibromyalgia, where no objective medical tests exist, subjective patient testimony must be given significant weight in disability benefit decisions, reversing a previous denial for a woman suffering from the condition and emphasizing the importance of recognizing such illnesses in the disability process.
A large genetic study has identified 26 genetic regions linked to fibromyalgia, revealing that the condition primarily originates in the brain's neural circuits that control pain sensitivity, rather than in muscles or joints. The findings suggest fibromyalgia is related to nervous system hypersensitivity and shares genetic links with other disorders like chronic fatigue and PTSD, offering new avenues for early detection and targeted treatments.
Low-dose naltrexone (LDN), an old generic drug, is gaining attention as a promising off-label treatment for fibromyalgia, showing potential to reduce pain, fatigue, and brain fog, despite limited large-scale studies. Many patients and some doctors report significant benefits, and ongoing research suggests it may help manage symptoms by reducing nerve inflammation, though more rigorous trials are needed. It is often used as a last resort but could be considered earlier, with minimal side effects and low cost.
Tonix Pharmaceuticals' drug Tonmya has received FDA approval for treating fibromyalgia in adults, marking the first new therapy in over 15 years for this condition. The medication, a non-opioid, once-daily sublingual tablet, demonstrated significant pain reduction in clinical trials and is expected to be available in the US by late 2025.
The FDA has approved Tonmya, a new treatment for fibromyalgia developed by Tonix Pharmaceuticals, marking the first new FDA-approved fibromyalgia drug in over 15 years. The drug is a once-daily sublingual tablet shown to significantly reduce pain in clinical trials. Following the announcement, Tonix's stock initially surged but then declined, reflecting market volatility and investor reactions.
Tonix Pharmaceuticals received FDA approval for Tonmya™, a non-opioid, sublingual tablet for fibromyalgia in adults, marking the first new treatment in over 15 years. The drug demonstrated significant pain reduction in Phase 3 trials and is expected to launch in Q4 2025, targeting over 10 million affected U.S. adults.
A woman with fibromyalgia experienced increased pain and inflammation after stopping Mounjaro, a medication she used for weight loss that also appeared to reduce her fibromyalgia symptoms, highlighting its potential anti-inflammatory effects beyond weight management.
Researchers at the Salk Institute identified a new brain circuit involving CGRP neurons in the thalamus that mediates the emotional aspect of pain, challenging traditional views and offering potential new treatments for chronic pain and related psychiatric conditions like PTSD and migraines.
Angie Ehrenzweig lost 100 pounds in one year after addressing underlying health issues like fibromyalgia, insulin resistance, and metabolic syndrome with the help of Dr. Whit Roberts at Health Utah. Her journey highlights the importance of resolving health problems before effective weight loss can occur. Health Utah offers comprehensive evaluations and personalized protocols to tackle such issues, emphasizing the need for a holistic approach to weight loss.
Angie Ehrenzweig lost 100 pounds in a year with the help of Health Utah after struggling with fibromyalgia, extreme fatigue, insulin resistance, depression, systemic inflammation, and metabolic syndrome. Dr. Whit Roberts, D.C. ran a specialized scan and used a proprietary questionnaire to identify health problems contributing to her weight issues. The clinic's protocols addressed her conditions, including insulin resistance, through a combination of therapies, supplements, and dietary changes. Health Utah is offering a discounted weight loss package for two people to encourage support in weight loss journeys.
Two recent studies from UT Health Austin provide crucial insights into long COVID, helping to define its symptoms and differentiate it from other conditions. One study found that long COVID patients experienced complex and disabling symptoms, with fatigue, "brain fog," and difficulty concentrating being the most common. Another study introduced a blood test that can accurately differentiate between long COVID and fibromyalgia, offering hope for quicker and more accurate diagnoses and targeted interventions. These findings aim to improve care for the millions of individuals still grappling with the long-term effects of the pandemic.
A woman shares her decades-long struggle with chronic fatigue syndrome (CFS) and fibromyalgia, detailing the dismissive treatment she received from doctors and the challenges of managing her symptoms. After years of misdiagnoses, she finally received a proper diagnosis and treatment plan from a specialist, allowing her to regain some level of functioning. The article also discusses the stigma attached to CFS and the recent attention it has received due to the similarities with long-covid, shedding light on the struggles faced by those with post-viral illnesses.