Tag

Fructose

All articles tagged with #fructose

Sugary drinks daily linked to almost triple stomach cancer risk, study shows
health5 days ago

Sugary drinks daily linked to almost triple stomach cancer risk, study shows

Researchers analyzing data from more than 100,000 participants in two long-running cohorts found that consuming at least one sugary drink daily was linked to nearly a threefold increase in gastric (stomach) cancer risk, while artificially sweetened beverages showed no such association. The study, which adjusts for other risk factors, shows an association—not causation—and the mostly white healthcare-professional sample limits generalizability; further research is needed to confirm findings in diverse populations and to clarify the role of fructose.

Sugary drinks may raise stomach cancer risk, large cohort study finds
health6 days ago

Sugary drinks may raise stomach cancer risk, large cohort study finds

A large Harvard-affiliated cohort study found that consuming at least one sugar-sweetened beverage per day was linked to a 2.45-fold higher risk of gastric cancer compared with consuming less than one per month, with higher fructose intake tied to greater risk; the study is observational and cannot prove causation, and findings need replication across diverse populations.

Fructose and Cancer: The Research Is Complex, Not Causative
health7 days ago

Fructose and Cancer: The Research Is Complex, Not Causative

Preclinical studies indicate fructose may affect cancer progression through altered tumor metabolism and liver processing, potentially aiding spread in some contexts, but this does not prove that fructose causes cancer. Experts advise limiting added sugars and sugar-sweetened beverages while allowing natural fructose from fruits and vegetables as part of a nutritious diet.

Sugary Signal: Fructose From Senescent Cancer Cells May Drive Ovarian Tumor Spread
science15 days ago

Sugary Signal: Fructose From Senescent Cancer Cells May Drive Ovarian Tumor Spread

A Nature Aging study shows fructose secreted by chemotherapy‑induced senescent ovarian cancer cells acts as a signaling molecule that reduces cell adhesion and promotes detachment and metastasis in cell cultures and mice; altering fructose metabolism blocked movement, and high-fructose intake worsened spread in animals, suggesting dietary fructose restriction and senolytic therapies could improve treatment outcomes—though findings are preclinical and not yet applicable to humans.

health19 days ago

Fructose as a Hidden Signal May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute found that fructose released by treatment-surviving ovarian cancer cells acts as a signal that weakens cell–cell adhesion and promotes detachment and spread. The effect can occur even without chemotherapy, and higher dietary fructose may influence tumor behavior, with cholesterol-lowering statins also weakening cancer cell adhesion. The study, published in Nature Aging, raises the possibility that this mechanism could occur in other torso-spreading cancers, though clinical studies are needed.

Sweet Signal: Fructose Secreted by Chemo-Treated Cells May Drive Ovarian Cancer Spread
health-and-medicine21 days ago

Sweet Signal: Fructose Secreted by Chemo-Treated Cells May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute report that fructose released by chemotherapy-surviving ovarian cancer cells acts as a signal to neighboring tumor cells, promoting detachment and metastatic spread. In preclinical tests, high dietary fructose could enhance cancer spread by lowering cholesterol production in nearby cells, weakening cell adhesion; the finding also suggests interactions with cholesterol-lowering drugs (statins). While intriguing, these effects have not been tested in patients, and researchers caution against changing medications yet. More studies are planned to see if this pathway affects other cancers and whether diet or statin use could influence outcomes.

Fructose may fuel cancer spread after chemotherapy, study suggests
science24 days ago

Fructose may fuel cancer spread after chemotherapy, study suggests

A new study finds the sugar fructose produced by chemotherapy-surviving tumor cells can signal neighboring cancer cells to spread, potentially affecting ovarian cancer progression and raising questions about diet and statin interactions. The findings are preclinical and suggest nutrition could influence cancer progression, but more research is needed before changing patient care.

Sorbitol May Fuel Fatty Liver When Gut Bacteria Falter
health2 months ago

Sorbitol May Fuel Fatty Liver When Gut Bacteria Falter

A Washington University study shows sorbitol can be converted to fructose in the liver when gut bacteria that normally degrade it are depleted, leading to fat accumulation in the liver in zebrafish and suggesting higher MASLD risk with excessive sorbitol intake or disrupted gut microbiota; gut bacteria may mitigate this by metabolizing sorbitol to harmless byproducts under normal conditions.

Processed Fructose in Everyday Foods Linked to Metabolic Disease
nutrition4 months ago

Processed Fructose in Everyday Foods Linked to Metabolic Disease

A Healthline summary highlights a Nature Metabolism review suggesting that fructose—especially from ultra-processed foods and sugar-sweetened beverages—may drive obesity and metabolic diseases by promoting fat production in the liver and disrupting metabolic pathways, with cautions that whole fruit is fine and a focus on reducing added fructose in processed foods.

Fructose: Not Just a Calorie, but a Metabolic Trigger Linked to Obesity
science4 months ago

Fructose: Not Just a Calorie, but a Metabolic Trigger Linked to Obesity

A Nature Metabolism review argues fructose acts as a distinct metabolic signal from glucose, promoting fat production and lowering cellular energy, which may contribute to obesity, insulin resistance, and metabolic syndrome. The analysis notes fructose is consumed in common sweeteners like sucrose and high-fructose corn syrup and can also be produced internally from glucose, highlighting health risks beyond calories.

Fructose Found to Drive Metabolic Disease Beyond Calories
health4 months ago

Fructose Found to Drive Metabolic Disease Beyond Calories

A Nature Metabolism review argues that fructose acts as a distinct metabolic signal that promotes fat production and energy depletion, beyond simply adding calories; its effects may drive obesity, insulin resistance, and metabolic syndrome, and the authors highlight endogenous fructose production and rising free-sugar intake as ongoing health concerns.

Sugar smart: timing, type, and balance to avoid energy slumps
health-and-wellbeing7 months ago

Sugar smart: timing, type, and balance to avoid energy slumps

Sugar activates the brain’s reward system and comes as glucose or fructose, which are processed differently: glucose prompts insulin release and energy storage, while fructose is sent to the liver and can be converted to fat. In excess, both raise triglycerides and may raise heart- and liver-related risks; repeated insulin spikes can fuel inflammation. The so-called 'sugar rush' is largely a myth, and when a sugar-induced dip occurs, people tend to eat more later. Timing matters: morning glucose responses are usually more favorable, and having sugar as part of a balanced meal with fiber, healthy fats, and protein helps blunt spikes. Moderation is best; avoid late-day sugar and be cautious with sugar substitutes, which may impact the gut/oral microbiome and can, in some cases, convert to fructose. Given that many people regularly eat sugary snacks (about 84% daily, with 79% up to three), reducing intake is sensible rather than demonizing it.

Majority of Indian IT workers suffer from fatty liver, unaffected by calorie cuts
health8 months ago

Majority of Indian IT workers suffer from fatty liver, unaffected by calorie cuts

A high prevalence of fatty liver disease (84%) among Indian IT employees is linked to insulin resistance, high carbohydrate intake, and genetic factors, with sugar consumption—especially fructose—playing a key role in liver fat accumulation and inflammation, which can lead to serious liver and cardiovascular complications. Simply cutting calories or fat isn't enough; addressing insulin resistance and dietary habits is crucial.