Tag

Masld

All articles tagged with #masld

health22 days ago•10 min saved

Young-onset MASLD cirrhosis tied to genetics and diabetes, study finds

UC San Diego researchers define early-onset MASLD cirrhosis as cirrhosis before age 50, finding about 25% of MASLD-related cirrhosis cases fall in this group and are driven by a mix of inherited genetic risk and metabolic factors, notably type 2 diabetes; standard fibrosis tests that include age overlook roughly one-third of these patients, underscoring the need for earlier, more precise liver assessment to enable cancer surveillance as obesity and diabetes rise.

via News-Medical|

#cirrhosis #fatty-liver-disease #genetics

health25 days ago•44 min saved

Cutting Sugar and Fried Foods May Shield Against Fatty Liver Disease

A HuffPost health piece warns MASLD (metabolic dysfunction-associated steatotic liver disease, formerly fatty liver disease) affects about 25% of U.S. adults, with under 5% knowing they have it; the condition is largely preventable and reversible with a healthy diet. It highlights sugar as the main driver once it reaches the liver, though saturated fat also stresses liver cells, and cites three foods to cut—starting with sugar-sweetened beverages and fried foods (the third item isn’t shown in this excerpt)—with a large study linking fried foods to a 15% higher MASLD risk. Cutting added sugars and fried foods could lower liver-fat risk over time.

via BuzzFeed|

#diet #fatty-liver #health

health26 days ago•44 min saved

Sugar and Fried Foods Linked to MASLD: Diet Changes That Can Prevent Fatty Liver

A HuffPost health piece notes that metabolic dysfunction-associated steatotic liver disease (MASLD, formerly fatty liver disease) affects about 25% of U.S. adults, with fewer than 5% aware of their condition. MASLD is largely preventable (and possibly reversible) through diet and lifestyle changes. Key culprits include sugar—especially from sugar-sweetened beverages—as the main driver of liver fat and insulin resistance, plus saturated fats and fried foods. Reducing these foods can help lower MASLD risk and protect liver health, according to hepatologists quoted in the article.

via BuzzFeed|

#diet #health #insulin-resistance

health26 days ago•13 min saved

Three Foods to Cut to Help Prevent MASLD (Fatty Liver Disease)

About 1 in 4 U.S. adults have metabolic dysfunction-associated steatotic liver disease (MASLD), a largely undiagnosed but potentially reversible condition. The piece highlights three foods to minimize: sugar-sweetened drinks, fried foods, and refined carbohydrates, explaining how sugar drives fat buildup in the liver and how fat, refined carbs, and even alcohol contribute to MASLD risk. It also recommends a Mediterranean-style diet, fruit (especially berries), dark chocolate in moderation, and regular coffee as liver-friendly choices to help prevent MASLD.

via huffpost.com|

#diet #fatty-liver-disease #health

science1 month ago•56 min saved

MASH Unraveled: Molecular Drivers of Steatohepatitis and Cancer Risk in MASLD

This Nature review outlines how MASLD progresses to MASH through insulin resistance, lipid dysregulation and lipotoxicity, genetic risk variants (e.g., PNPLA3, TM6SF2, HSD17B13), adipose–immune dysfunction, fibrogenesis and gut–liver axis disturbances; it highlights progression to fibrosis, cirrhosis and hepatocellular carcinoma, and notes advances in polygenic risk scores and targeted therapies addressing lipogenesis, mitochondrial metabolism and bile acid signaling, underscoring MASLD/MASH as a multi‑organ disease with translational therapeutic potential.

via Nature|

#genetics #insulin-resistance #liver-disease

health1 month ago•43 min saved

Precision moves in MASH: a new era of tailored therapies

This Nature review maps the current and future treatment landscape for metabolic dysfunction‑associated steatohepatitis (MASH), noting that recent approvals (resmetirom and semaglutide) mark an inflection point for non‑cirrhotic disease and fibrosis. It highlights MASH heterogeneity with liver‑centric and cardiometabolic subsets, arguing that optimal therapy will need stratified or combinatorial approaches that target metabolic dysfunction, fibrogenesis, inflammation, and the gut–liver axis, alongside lifestyle modification. Advances in disease phenotyping and biomarkers are seen as enabling a shift toward personalized, mechanism‑driven therapy.

via Nature|

#biomarkers #health #liver-disease

health1 month ago•12 min saved

MASLD: the hidden liver disease rising with obesity and diabetes in the UK

UK researchers found MASLD (metabolic dysfunction-associated steatotic liver disease), formerly called non-alcoholic fatty liver disease, is being diagnosed more often but a large diagnostic gap remains. Linked to obesity and type 2 diabetes, MASLD risks are higher for overweight individuals, the over-50s and those with high blood pressure; the study suggests routine screening and a blood test to estimate liver fibrosis could help detect advanced disease earlier.

via The Independent|

#health #liver-disease #masld

health1 month ago•60 min saved

Eggs and Liver Health: A Hepatologist Explains the Nuanced View

A hepatologist notes that eggs sit in a gray area for liver health: they provide satiating protein and choline that can support the liver, but their cholesterol content means effects vary with overall diet and metabolic health. Studies on egg intake and MASLD/NAFLD conflict—some show higher risk with limited eggs, others show no association and suggest choline may be protective. For healthy individuals, 1–2 eggs daily can fit in a balanced diet, but those with high cholesterol may want to eat them less often. Emphasize liver-friendly breakfasts with whole foods (Greek yogurt or plant proteins, fiber-rich toast with avocado) and beverages like coffee/tea, while avoiding sugar-heavy pastries and fruit juice and limiting processed meats.

via AOL.com|

#breakfast #cholesterol #eggs

health1 month ago•80 min saved

Pantry Power: Spices and Teas That May Help Fatty Liver Health

Fatty liver disease affects about a quarter of adults worldwide. The article highlights pantry staples—saffron (Crocin II), turmeric, ginger, green tea, and garlic—as potential natural aids to reduce liver fat and inflammation, especially when combined with weight loss, regular exercise, and a balanced diet; it also notes caution with high-dose saffron or supplements and recommends using these foods in food rather than relying on supplements.

via Woman's World|

#fatty-liver #green-tea #health

health2 months ago•7 min saved

Beyond Booze: 9 Everyday Habits That Could Harm Your Liver

Nine everyday factors beyond alcohol can silently stress the liver, per Dr. Pramod Kumar D A: refined fructose in drinks and packaged foods that can contribute to MASLD (formerly NAFLD); risk from mixing acetaminophen-containing medicines; herbal supplements can still harm the liver; chronic sleep deprivation disrupts the liver’s circadian rhythm; excessive vitamin A from supplements; exposure to household chemicals; secondhand smoke; hidden trans fats in processed foods; and dehydration. Practical steps include reading labels, avoiding unnecessary supplements, choosing water over sugary drinks, maintaining a consistent 7–9 hour sleep schedule, ventilating spaces during cleaning or painting, staying hydrated, and keeping a healthy weight through activity.

via The Times of India|

#health #liver-health #masld

health3 months ago•9 min saved

Liver Health Fever Sparks Supplement Surge, Doctors Warn Against Quick Fixes

Rising interest in liver health is driving a surge in supplements and online content, but hepatologists warn that most products lack solid evidence and can be harmful; the liver’s role extends beyond detox, and the recommended approach is maintaining a healthy weight, a Mediterranean-style diet, regular exercise, limited alcohol, and routine liver-screening tests to monitor MASLD/NAFLD risk.

via Business Insider|

#health #liver-disease #liver-health

health3 months ago•7 min saved

Black Coffee May Help the Liver, But It's Not a Cure

Emerging research suggests regular black coffee is associated with healthier liver markers and a lower risk of progression to advanced fibrosis in fatty liver disease (MASLD), likely due to caffeine, chlorogenic acid, and antioxidants that reduce inflammation and oxidative stress. Benefits appear with moderate intake (about 2–3 cups daily) of black coffee; sugary or high-calorie coffee drinks can negate these effects. Coffee should complement, not replace, lifestyle measures like weight management, exercise, diet, and medical care.

via The Times of India|

#antioxidants #coffee #fatty-liver

health4 months ago•46 min saved

Dual-agonist survodutide reduces liver fat and weight in phase 3 MASLD trial

In the SYNCHRONIZE-MASLD phase 3 trial, 216 adults with obesity and metabolic dysfunction-associated steatotic liver disease received weekly survodutide 6.0 mg or placebo for 48 weeks. Survodutide met both co-primary endpoints, with 84.2% achieving ≥30% reduction in liver fat content (MRI-PDFF) versus 24.3% on placebo, and significant weight loss compared with placebo. About six in ten treated participants reached normalization of liver fat. The study used a dose-escalation period to 6.0 mg followed by a maintenance phase and included extensive safety monitoring. Secondary endpoints showed favorable changes in liver enzymes, liver stiffness/volume, insulin resistance, and other noninvasive liver tests. These results support survodutide as a potential therapy for obesity and MASLD, with data sharing and ongoing follow-up planned.

via Nature|

#health #masld #mri-pdff

health4 months ago•8 min saved

Sorbitol May Fuel Fatty Liver When Gut Bacteria Falter

A Washington University study shows sorbitol can be converted to fructose in the liver when gut bacteria that normally degrade it are depleted, leading to fat accumulation in the liver in zebrafish and suggesting higher MASLD risk with excessive sorbitol intake or disrupted gut microbiota; gut bacteria may mitigate this by metabolizing sorbitol to harmless byproducts under normal conditions.

via Food Safety Magazine|

#fructose #gut-microbiome #health

wellness4 months ago•52 min saved

Green Mediterranean Plan Reverses Fatty Liver and Boosts Weight Loss

MASLD (formerly NAFLD) can improve with lifestyle changes and, for some patients, medications. The article recommends swapping refined carbs for leafy greens and liver-friendly foods like avocado, berries, apples, eggs, wild salmon, walnuts and flaxseed; adopting a Green Mediterranean pattern rich in polyphenols; sipping coffee or green tea and avoiding drinks with added sugar; moving about 30 minutes most days plus more daily steps; prioritizing 7–8 hours of sleep, finishing meals 2–3 hours before bed, and using a 10-hour eating window; and, for certain patients, prescription rezdiffera/resmetirom (FDA-approved for NASH). Ozempic is used off-label by some clinicians to address obesity/insulin resistance, and statins may lower cardiovascular risk in MASLD. Many readers report improved liver fat and weight loss with these strategies, but medical guidance is essential for personalized care.

via Woman's World|

#green-mediterranean-diet #masld #nafld