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Masld

All articles tagged with #masld

CBD and CBG Reprogram Liver Energy to Reverse Fatty Liver in Mice
health13 days ago

CBD and CBG Reprogram Liver Energy to Reverse Fatty Liver in Mice

Israeli researchers found that non-psychoactive cannabis compounds CBD and CBG can reverse liver damage in obese mice with MASLD by reprogramming liver energy use, boosting phosphocreatine reserves and lysosomal activity, and improving insulin resistance and lipid profiles. The treated mice showed reduced fat accumulation and inflammation without dietary changes, suggesting a new metabolic pathway to target in MASLD. However, these results are preclinical, and human relevance requires careful dosing considerations and clinical trials, as consumer CBD/CBG products vary in purity and concentration.

via Daily Mail|
#cbd#cbg#fatty-liver
CBD and CBG Reprogram Liver Energy to Reverse Fatty Liver in Mice
science23 days ago

CBD and CBG Reprogram Liver Energy to Reverse Fatty Liver in Mice

In obese mice fed a high-fat diet, CBD and CBG improved liver function, reduced hepatic fat, lowered blood lipids, and enhanced insulin sensitivity, with CBG generally more effective. The benefits appear to arise from reprogramming hepatic energy and lysosomal pathways rather than activating classic cannabinoid receptors, and were achieved via abdominal injections. While promising for MASLD, human relevance remains to be tested and CBD product quality is variable.

via ScienceAlert|
#cannabinoids#cbd#cbg
CBD and CBG Could Cut Fatty Liver Risk and Cholesterol, Study Says
health1 month ago

CBD and CBG Could Cut Fatty Liver Risk and Cholesterol, Study Says

New research shows non-psychoactive cannabis compounds CBD and CBG can significantly reduce liver fat and cholesterol, improve liver energy metabolism, and restore cellular cleanup (lysosomal) function, offering a plant-based approach to MASLD, the world’s most common chronic liver disease. The study also found both compounds normalize blood sugar, with CBG showing stronger effects on fat reduction and insulin sensitivity; further research is needed to translate these findings into treatments.

via Good News Network|
#cannabis#cbd#cbg
Indole from Healthy Gut Bacteria Could Shield Children from Fatty Liver Disease
health2 months ago

Indole from Healthy Gut Bacteria Could Shield Children from Fatty Liver Disease

University of Oklahoma researchers found that giving indole, a compound produced by beneficial gut bacteria, to pregnant and nursing mice on a high-fat, high-sugar diet significantly lowered fatty liver risk and improved metabolic health in their offspring later in life. The protective effect correlated with activation of the gut AHR signaling pathway and favorable shifts in liver lipids, including ceramides. Transferring the protected offspring’s microbiome to other mice also conferred protection, underscoring the microbiome’s central role. While human applications require more study, the work suggests early prevention of MASLD through maternal microbiome modulation.

via SciTechDaily|
#gut-microbiome#health#indole
Two Common Heart Drugs Show Promise in Reversing Fatty Liver Disease
health5 months ago

Two Common Heart Drugs Show Promise in Reversing Fatty Liver Disease

A study in animal models suggests that a combination of two common heart medications, pemafibrate and telmisartan, may reverse fat accumulation in the liver, offering a potential new treatment for early-stage fatty liver disease (MASLD). However, further clinical research is needed before these drugs can be recommended for human treatment.

via Medical News Today|
#fatty-liver-disease#health#heart-drugs
Consuming Diet Soda Daily Significantly Increases Liver Disease Risk
health6 months ago

Consuming Diet Soda Daily Significantly Increases Liver Disease Risk

A new study suggests that consuming over one can of both regular and diet sodas daily may increase the risk of liver disease, particularly MASLD, with low or non-sugar-sweetened beverages also linked to higher liver-related mortality. The findings challenge the perception that diet drinks are healthier, highlighting the potential liver health risks associated with both types of beverages and emphasizing water as the safest choice.

via Medical News Today|
#artificial-sweeteners#health#health-risks