Tag

Galapagos

All articles tagged with #galapagos

business18 days ago•8 min saved

Gilead to Acquire Ouro Medicines to Fast-Track T Cell Engager for Autoimmune Diseases

Gilead Sciences agreed to buy Ouro Medicines for $1.675 billion upfront plus up to $500 million in milestones to add OM336, a BCMAxCD3 T cell engager, to its inflammation portfolio. OM336 has shown rapid B cell depletion with a favorable safety profile in Phase 1/2 data and has FDA Fast Track and Orphan Drug designations, with registrational studies expected in 2027. Gilead is also in advanced talks for a collaboration with Galapagos, under which Galapagos would fund half of upfront and milestone payments, absorb Ouro’s operating assets, and receive 20-23% royalties on net sales while Gilead retains worldwide commercialization rights. The combined effort aims to accelerate immune-reset therapies for autoimmune diseases and potentially deliver durable, drug-free remission through BCMA-targeted T cell engagers.

via Business Wire|

#autoimmune-diseases #bcmaxcd3 #business

history7 months ago•9 min saved

Eden: A Harrowing Tale of Utopia, Betrayal, and Human Nature

A true story from the 1930s about European settlers on a Galapagos island, which turned into a tale of betrayal, violence, and mysterious disappearances, is dramatized in the film Eden and explored in the documentary The Galapagos Affair, highlighting the complex personalities and events that led to an enduring unsolved mystery.

via BBC|

#1930s #eden-film #galapagos

science9 months ago•3 min saved

Galápagos Tomatoes Show Signs of Reversing Evolution, Revealing Ancient Traits

Scientists have discovered that wild tomatoes in the Galápagos Islands are evolving backwards, regaining ancient traits lost millions of years ago, challenging traditional views of evolution and opening new avenues for genetic research and crop improvement.

via The Daily Galaxy|

#evolution #galapagos #genetic-reversal

science9 months ago•2 min saved

Galapagos Tomatoes Show Signs of Reverse Evolution

Researchers have documented a rare example of reverse evolution in wild tomatoes on the Galapagos Islands, where some plants have reverted to ancestral chemical traits, suggesting environmental pressures can drive species back along their evolutionary path, with potential implications for genetic engineering and agriculture.

via ScienceAlert|

#adaptation #evolution #galapagos

science9 months ago•2 min saved

Galápagos Wild Tomatoes Show Signs of De-Evolving

Researchers studying wild tomatoes in the Galápagos Islands discovered that plants on the younger western islands are producing alkaloids identical to those of ancient ancestors, suggesting a reversion to ancestral traits possibly as an adaptation to harsher environments, highlighting the flexibility and complexity of evolutionary processes.

via BBC Wildlife Magazine|

#adaptation #ancestral-traits #evolution

science9 months ago•4 min saved

Galápagos Tomatoes Undergo Silent De-Evolution

Scientists studying wild tomatoes in the Galápagos Islands have observed a rare case of reverse evolution, where the plants are reverting to an ancient chemical state by producing alkaloids similar to those found in eggplants, likely driven by environmental factors on younger islands. This discovery challenges traditional views of evolution as a one-way process and suggests that traits can re-emerge through genetic changes, with potential implications for agriculture and medicine.

via Phys.org|

#alkaloids #galapagos #plant-defense

natural-disasters2 years ago•1 min saved

"Uninhabited Galapagos Island Volcano Erupts, Lava Flows to Sea"

The La Cumbre volcano on Fernandina island in the Galapagos has erupted, sending lava flowing down its sides toward the sea. While posing no risk to humans, the eruption threatens the island's unique wildlife, including iguanas, penguins, and flightless cormorants. The Galapagos Islands are famous for their role in Charles Darwin's theory of evolution.

via The Associated Press|

#ecuador #galapagos #lava-flow

natural-disasters2 years ago•1 min saved

"Uninhabited Galapagos Island Volcano Erupts, Lava Flows to Sea"

via ABC News|

#ecuador #galapagos #lava-flow

science2 years ago•3 min saved

"Unlikely Encounters: Kelp in Galapagos, Polar Bears in Bahamas"

Marine scientist Salomé Buglass made a surprising discovery of a kelp forest thriving in deep, tropical waters in the Galapagos. Kelp usually grows in cooler waters and requires light to survive, making this find unusual. The kelp forest provides habitat for various species and stores carbon, making it important for biodiversity and climate change. Researchers believe it may be a new species or a relic from a colder past, and further genetic sequencing is needed to confirm.

via NPR|

#biodiversity #climate-change #galapagos

environment3 years ago•3 min saved

Pristine Coral Reef Discovered in Deep-Sea Galapagos

Scientists exploring a previously unexplored part of the Galápagos marine reserve have discovered deep-sea coral reefs in pristine condition, raising hopes that healthy reefs can still thrive despite coral being in crisis due to record sea surface temperatures and ocean acidification. The discovery shows the effectiveness of conservation actions and effective management. The newly discovered reefs are potentially of global significance and could help scientists reconstruct past ocean environments to understand modern climate change. Ecuador is collaborating with its northern neighbours on a regional marine corridor initiative to protect and responsibly manage the ocean.

via The Guardian|

#conservation #deep-sea-coral-reefs #environment