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Hba1c

All articles tagged with #hba1c

Fruit Sugar Isn’t the Villain: Whole Fruits May Improve Diabetes Markers
health3 days ago

Fruit Sugar Isn’t the Villain: Whole Fruits May Improve Diabetes Markers

New evidence shows that naturally occurring fruit sugar is not the same as added sugars. A 2026 meta-analysis found whole-fruit consumption is linked to lower HbA1c and fasting glucose in people with type 2 diabetes, and a BMJ analysis showed higher intake of several whole fruits is associated with a reduced risk of type 2 diabetes; fruit juice is linked with higher risk. Health guidelines from ADA and Mayo Clinic favor whole fruit (fresh, frozen, or canned without added sugars) and pairing fruit with protein or fat to blunt blood sugar spikes.

via AOL.com|
#diabetes#fiber#fruit
Orforglipron tops oral GLP-1 rivals in 52-week diabetes trial
health1 month ago

Orforglipron tops oral GLP-1 rivals in 52-week diabetes trial

A 52-week Phase 3 trial in 1,698 adults with type 2 diabetes found that Eli Lilly’s orforglipron, an oral small‑molecule GLP-1 drug, reduced HbA1c by about 1.71–1.91 percentage points and produced greater weight loss (6.1–8.2 kg) compared with oral semaglutide (1.47 HbA1c reduction and ~5.3 kg weight loss). However, tolerability favored semaglutide, with around 59% reporting GI side effects on orforglipron versus 37–45% on semaglutide and higher discontinuation (~10% vs ~4–5%). Orforglipron’s small‑molecule, no‑refrigeration profile could improve access in lower‑income countries, but there’s no head‑to‑head with injectable GLP‑1s yet and long‑term adherence remains to be seen.

via ScienceDaily|
#glp-1#hba1c#health
Sweeteners May Have Hidden Metabolic Costs, New Analysis Finds
health1 month ago

Sweeteners May Have Hidden Metabolic Costs, New Analysis Finds

A review of 21 randomized trials links artificial and low-calorie sweeteners to higher fasting insulin and HbA1c, with a possible reduction in insulin sensitivity; gut microbiome changes may be involved, and higher consumption could relate to greater cardiometabolic risk, though causality isn’t proven. While avoiding large amounts of added sugar is prudent, replacing sugar with these sweeteners may be better than sugar, but not risk-free.

via U.S. News & World Report|
#artificial-sweeteners#gut-microbiome#hba1c
Triple-action diabetes jab delivers major weight and sugar reductions
health2 months ago

Triple-action diabetes jab delivers major weight and sugar reductions

Phase 3 results show retatrutide, a weekly triple-hormone jab targeting GLP-1, GIP and glucagon, significantly lowers HbA1c and promotes substantial weight loss in type 2 diabetes after 40 weeks (HbA1c down ~1.7–1.9 points; weight loss ~11.5–15.3% vs 2.6% placebo), with mostly mild-to-moderate side effects. The drug could offer greater improvements than current therapies, but head-to-head trials and long-term data are still needed.

via The Guardian|
#clinical-trial#diabetes#gut-hormones