Tag

Levothyroxine

All articles tagged with #levothyroxine

medicine2 hours ago•12 min saved

Severe LDL-C Elevations Reversed by Restoring Thyroid Hormone in a Post-Thyroidectomy Patient

A 47-year-old woman with autoimmune Hashimoto’s thyroiditis who had total thyroidectomy showed dramatic LDL-C elevations during profound hypothyroidism, driven by reduced LDL receptor activity and increased PCSK9; LDL-C levels improved markedly when euthyroidism was restored with levothyroxine. The case highlights hypothyroidism as a reversible, non-genetic cause of severe hypercholesterolemia and emphasizes evaluating thyroid function before diagnosing familial hypercholesterolemia or initiating lipid-lowering therapy.

via Cureus|

#hypothyroidism #ldl-c #levothyroxine

health2 months ago•3 min saved

LT3+LT4 Therapy May Elevate Psychiatric Morbidity Risk in Autoimmune Hypothyroidism

In a Swedish nationwide cohort of 184,266 adults with autoimmune hypothyroidism, starting liothyronine (LT3) in combination with levothyroxine (LT4) was linked to a 43% higher risk of any psychiatric morbidity (adjusted HR 1.43) versus LT4 alone, with similar increases for affective/anxiety (HR 1.44) and psychotic morbidity (HR 1.46). The associations held across sexes and ages under 75, and were especially elevated for psychotic morbidity among women and those under 30. Limitations include retrospective design and potential confounding; authors note LT3 use may reflect emerging mental-health issues rather than causation.

via Medscape|

#cohort-study #health #hypothyroidism

health1 year ago•4 min saved

Widely Used Thyroid Drug May Accelerate Bone Loss in Older Adults

A study presented at the Radiological Society of North America suggests that levothyroxine, a common thyroid medication, may lead to reduced bone mass and density in older adults with normal thyroid levels. Conducted by Johns Hopkins University researchers, the study involved 81 participants over 65 and found bone loss over a 6-year period. This raises concerns about the potential overprescription of levothyroxine and its side effects, including increased osteoporosis risk, in older adults.

via Medical News Today|

#bone-loss #health #hypothyroidism

health1 year ago•2 min saved

Thyroid Medication Linked to Potential Bone Weakening

New research indicates that levothyroxine, a common thyroid medication prescribed to older adults, may be linked to increased bone loss. The study, involving 445 participants with normal thyroid levels, found that those taking levothyroxine experienced greater bone mass and density loss. Researchers suggest that even when following current guidelines, the medication could pose risks, urging patients to regularly consult with their doctors and assess the necessity of their treatment. These findings were presented at the Radiological Society of America meeting.

via Newsmax|

#bone-loss #health #hypothyroidism

health1 year ago•4 min saved

Common Prescription Drug Linked to Osteoporosis Risk

New research from Johns Hopkins suggests that levothyroxine, a common thyroid medication taken by millions of Americans, may increase the risk of bone density loss, potentially leading to osteoporosis. The study found that even patients with normal thyroid-stimulating hormone levels experienced greater bone mass loss over six years. Experts recommend that patients discuss treatment risks with their doctors, as the drug may be overprescribed, particularly in older adults without hypothyroidism.

via Daily Mail|

#bone-density #health #johns-hopkins-study

medical-science-news1 year ago•3 min saved

Levothyroxine Tied to Increased Osteoporosis Risk in Seniors

A study presented at the Radiological Society of North America meeting suggests that levothyroxine, a common medication for hypothyroidism, may be linked to bone density loss in older adults, even when thyroid hormone levels are within the normal range. The research, using data from the Baltimore Longitudinal Study of Aging, found that levothyroxine users experienced greater bone mass loss over a median follow-up of 6.3 years compared to non-users. The study highlights the need for regular monitoring and risk-benefit assessments for older adults on levothyroxine.

via News-Medical.Net|

#aging #bone-density #hypothyroidism

health2 years ago•5 min saved

The Importance of Annual Thyroid Medication Dose Rechecks

Overmedication with levothyroxine, a medication for an underactive thyroid, may be linked to an increased risk of dementia, according to a recent study. The study found that patients taking an excessively high dose of levothyroxine had a higher likelihood of receiving a new cognitive disorder diagnosis. Endocrinologists are calling for more research and recommend checking TSH levels every year, especially in older patients, to determine if the dose of thyroid medication should be adjusted or stopped. Taking too much thyroid medication can also lead to other health risks such as atrial fibrillation and fractures.

via Verywell Health|

#cognitive-decline #dementia-risk #health

health3 years ago•4 min saved

Thyroid Dysfunction on the Rise: Desiccated Extract and Dioxin Exposure to Blame

Prescriptions for desiccated thyroid extract (DTE) to treat newly diagnosed hypothyroidism nearly doubled between 2010 and 2020 in the United States, while prescribing of first-line levothyroxine monotherapy dropped, new research has found. The nonlevothyroxine therapies were more commonly prescribed in the west and southwestern United States, while levothyroxine monotherapy was more frequent in the northwest and upper midwest, and also in states with higher densities of primary care physicians and endocrinologists. The shift in first-line treatment was unexpected, and the reasons for the increase in DTE use are unclear.

via Medscape|

#desiccated-thyroid-extract #endocrinology #health