All articles tagged with #statin side effects
A major meta-analysis in The Lancet suggests that while statins cause minor increases in muscle pain, liver enzyme changes, and diabetes risk, they do not significantly cause memory loss, depression, or sleep issues. Most reported muscle complaints are not actually caused by the drug, yet poor adherence remains a critical issue.
A Nature feature shows that the X and Y chromosomes influence health beyond hormones. Some X-linked genes escape inactivation, driving sex differences in autoimmunity, cancer, cardiovascular and neurodevelopmental conditions; in mice, the statin side effects were linked to an Xi escape gene, Kdm5c, with DHA supplementation partially reversing the metabolic effects. Overall, Xi and Y gene expression affect about 21% of genes in tested cells, underscoring the need to study XX versus XY biology to understand disease risk and drug responses.