Tag

Brain Networks

All articles tagged with #brain networks

Psilocybin Reveals Hidden Order Beneath Brain Chaos, Study Finds
science4 days ago

Psilocybin Reveals Hidden Order Beneath Brain Chaos, Study Finds

Monash University researchers conducted a five-year, open-label study with 62 healthy adults to map brain changes after psilocybin using fMRI, EEG, machine learning and questionnaires. They found a reduction in modular brain organization and a reconfiguration of networks—especially the default mode network—producing a “hidden order” linked to participants’ positive experiences and a sense of unity. The strongest global brain changes occurred when listening to ethereal music and were attenuated by visual input like watching a movie, highlighting the role of context in psychedelic effects. While findings may inform psychedelic therapies, the study lacked a placebo group and involved healthy volunteers, not patients.

When the brain mispredicts: the reality of functional neurological disorder
health-and-families8 days ago

When the brain mispredicts: the reality of functional neurological disorder

Functional neurological disorder (formerly hysteria/conversion disorder) causes real, disabling symptoms despite normal brain tests. Neuroscience links symptoms to brain networks that predict movement and sensation, with mismatches driving the disturbance. Though common—millions affected in the US—care access is limited and stigma persists, but multidisciplinary treatments and clinician belief can improve outcomes.

Childhood Trauma May Rewire Brain Networks That Fuel Procrastination in Adulthood
mental-health14 days ago

Childhood Trauma May Rewire Brain Networks That Fuel Procrastination in Adulthood

A neuroimaging study of over a thousand participants links childhood trauma to higher adult procrastination, with trait anxiety and reduced self-control mediating the relationship. The researchers identify brain connectivity patterns—especially involving the frontoparietal and salience networks and stronger visual-cerebellar connections—that predict trauma exposure and relate to procrastination, aligning with the triple-network model. However, the cross-sectional design and modest effect sizes limit causal conclusions, and more diverse, longitudinal work is needed.

science25 days ago

One-Dose Rapamycin Triggers Rapid Reversal of Autism-Like Brain Activity in Adult Mice

A single dose of rapamycin given to adult mice exposed to maternal inflammation reverses most autism-like brain and behavioral changes within about two hours by rapidly normalizing neural activity and network patterns, likely through dampening mTOR signaling and restoring excitation–inhibition balance. The effects are fast but temporary and do not repair underlying structural brain changes; long-term use carries toxicity risks, but the findings point to new targets such as sensory circuit modulation rather than rapamycin itself.

Psychedelic Case Hints at Hidden Abilities in Alzheimer's Brain
science2 months ago

Psychedelic Case Hints at Hidden Abilities in Alzheimer's Brain

An elderly woman with advanced Alzheimer's showed temporary improvements in speech, independence and orientation after psilocybin mushroom sessions. The report is a single case, with no biomarkers or control group, and does not prove a reversal of the disease or establish safety. It raises questions about whether psychedelics can temporarily modify brain-network communication and uncover latent abilities, underscoring the need for controlled research and caution given potential risks for older adults.

Psychedelic Session Triggers Temporary Speech Revival in Advanced Alzheimer’s Case
science2 months ago

Psychedelic Session Triggers Temporary Speech Revival in Advanced Alzheimer’s Case

An octogenarian with advanced Alzheimer’s showed a temporary return of fluent speech and personal-memory recall about 19 hours after a supervised 5-gram psilocybin dose, with weeks of improved alertness and independence, and a second supervised 3-gram session suggesting further benefit. This is a single uncontrolled case with no biomarkers, so it does not prove efficacy or safety and cannot be generalized; potential mechanisms include 5-HT2A receptor signaling, increased BDNF, dendritic spine growth, and temporary restructuring of brain networks, highlighting the need for controlled trials and caution against unsupervised use.

Brief Glimmer of Function: Psilocybin Sparks Temporary Gains in an Alzheimer’s Case
science2 months ago

Brief Glimmer of Function: Psilocybin Sparks Temporary Gains in an Alzheimer’s Case

A case report describes an elderly Japanese-American woman with advanced Alzheimer’s who ingested psilocybin mushrooms in two supervised sessions and, within hours to weeks, showed improved alertness, memory recall, mobility and independence; however, the observations come from a single patient with no biomarkers, controls, or standardized testing, so they cannot prove that psilocybin reverses Alzheimer’s or guide therapy. The report suggests possible temporary changes in brain networks and neuroplasticity but remains unproven, and safety concerns and the lack of controlled data mean this should not inform self-treatment outside supervised research.

Ozempic May Rewire the Brain, Changing Mood, Motivation and Cravings
science2 months ago

Ozempic May Rewire the Brain, Changing Mood, Motivation and Cravings

New research suggests GLP-1 drugs like Ozempic—used for obesity and diabetes—may reshape brain networks and influence appetite, mood, cognition and addiction. Early brain scans in teens and young women on GLP-1s showed increased connectivity in the salience network within months, hinting at direct neural effects or indirect changes via gut-brain pathways. Scientists are exploring roles beyond weight loss, including potential impacts on anxiety, compulsive thinking and addiction, while noting that long-term, developmental effects (especially in adolescents) remain unclear. Although some trials hint at neuroprotective signals, a major Alzheimer’s trial with a related drug failed to slow cognitive decline, underscoring that conclusions about brain health from GLP-1s are still uncertain and ongoing.

Brains Build, Not Break: Development Extends into the 30s, Not a 25-Year Cutoff
science7 months ago

Brains Build, Not Break: Development Extends into the 30s, Not a 25-Year Cutoff

New neuroscience shows brain maturation continues into the early 30s as neural networks become more efficient; the classic 'finish at 25' myth arose from earlier gray-matter studies and datasets ending around age 20, but latest research on white matter reveals ongoing segregation and integration until about 32. There is no magic switch at 25—adulthood is a prolonged construction zone, and you can support brain health through aerobic exercise, learning new skills, and cognitively challenging activities while minimizing chronic stress.

Neuroscientists uncover rhythmic pattern guiding brain networks
science10 months ago

Neuroscientists uncover rhythmic pattern guiding brain networks

Neuroscientists have discovered a repeating, clock-like rhythm in the brain that organizes large-scale network activity, cycling through different cognitive functions every 300 to 1,000 milliseconds. This structured cycle may help coordinate mental processes such as attention, memory, and sensory processing, and varies with age, genetics, and behavior, offering new insights into brain organization and potential implications for cognitive health and disorders.

Revolutionary Ultrasound Helmet Enables Non-Invasive Deep Brain Stimulation
science-and-technology10 months ago

Revolutionary Ultrasound Helmet Enables Non-Invasive Deep Brain Stimulation

Researchers have developed a novel ultrasound device capable of simultaneously stimulating multiple precise points in the brain non-invasively, using low-intensity ultrasound to reduce risks and enable visualization of brain activity, with potential applications for treating neurological and psychiatric disorders.