Tag

Epilepsy

All articles tagged with #epilepsy

New brain implant halts many seizures, boosting daily life for some epilepsy patients
health10 hours ago

New brain implant halts many seizures, boosting daily life for some epilepsy patients

Whitney Wilkinson, diagnosed with epilepsy at 12, now uses a responsive neurostimulator brain implant that senses seizures and delivers a millisecond pulse to stop them, greatly improving daily life; Intermountain Healthcare has implanted 100 devices in the last decade. The implant is approved for focal epilepsy, requires initial surgery (about a week in hospital) and battery replacement after roughly 10 years, and reduces seizures by about 75% for many patients, with some regaining driving ability and normal activities.

Danny Glover reveals Alzheimer's diagnosis, says life will change but he’ll live with it
entertainment10 days ago

Danny Glover reveals Alzheimer's diagnosis, says life will change but he’ll live with it

Danny Glover, 79, announced on the Today show that he has been diagnosed with Alzheimer's disease, saying he can 'live with it' but that life will change as it progresses; he credited his family for support and his daughter Mandisa stressed the importance of him controlling his own narrative. The actor, who received an honorary Oscar in 2022, also reflected on his career and past epilepsy battles, noting he hasn’t had a seizure since age 35 and emphasizing his focus on teaching younger generations about responsibility.

Insurance reversal clears DBS path for teen with treatment-resistant epilepsy
health1 month ago

Insurance reversal clears DBS path for teen with treatment-resistant epilepsy

A 13-year-old with drug-resistant epilepsy faced a denial for deep brain stimulation because it wasn’t FDA-approved for children; after NBC News coverage, Anthem Blue Cross Blue Shield approved DBS and later updated its policy to cover pediatric DBS for epilepsy, offering new hope for reducing seizure frequency and improving quality of life.

Panic attacks revealed epilepsy — a brain implant stopped the seizures
health3 months ago

Panic attacks revealed epilepsy — a brain implant stopped the seizures

A New York City actress misinterpreted recurring seizures as panic attacks for years until doctors diagnosed focal impaired awareness seizures. After SEEG pinpointed the seizure origin, she received a NeuroPace brain implant in 2018–2019; by July 2019 her seizures were gone, allowing her to return to work, and she has remained seizure-free since, though she continues daily meds and will need periodic battery replacements for the device.

Repurposed Antiemetic May Restore Brain’s Inhibitory Brake to Curb Epilepsy
science4 months ago

Repurposed Antiemetic May Restore Brain’s Inhibitory Brake to Curb Epilepsy

Researchers identified two molecules, prochlorperazine and CLP-257, that stabilize the KCC2 chloride transporter to restore GABAergic inhibition in epileptic tissue. In human brain slices they nearly abolished spontaneous interictal spikes, and in mouse models they reduced seizure frequency by about 40–55%, suggesting a promising repurposing path for treatment-resistant temporal lobe epilepsy (potentially in combination with benzodiazepines).

Promising antisense drug could alter Dravet syndrome in children
health4 months ago

Promising antisense drug could alter Dravet syndrome in children

An early-stage trial suggests the antisense drug zorevunersen is safe for children with Dravet syndrome and may dramatically reduce seizures, with the highest-dose group seeing 59%–91% fewer seizures after about 20 months and potential neurodevelopmental and quality-of-life benefits. The study involved 81 children (ages 2–18) in the UK and US and did not include a placebo; larger, controlled trials are underway, with results expected by 2028 to determine if the treatment can alter the disease course.

New drug brings life-changing relief to children with Dravet syndrome
health4 months ago

New drug brings life-changing relief to children with Dravet syndrome

A new drug, zorevunersen, delivered by spinal infusion, is showing strong promise for Dravet syndrome in children by boosting brain sodium channel activity and dramatically reducing seizures; early trials report up to 90% fewer seizures, with patients like Freddie Truelove moving from hundreds of daily seizures to a few per week and regaining normal activities. UK and US trials involve young children, starting from age two, at several hospitals, and while results are encouraging, Phase 3 data are needed before it becomes widely available.

Post-Seizure Sleep May Strengthen Epileptic Networks
science-and-health4 months ago

Post-Seizure Sleep May Strengthen Epileptic Networks

New Mayo Clinic findings indicate the brain may hijack memory-consolidation processes after a seizure, with nights of intensified deep (NREM) sleep and reduced REM sleep that strengthen seizure networks and potentially worsen epilepsy. This post-seizure consolidation could explain disease progression and points to a critical window for targeted neuromodulation therapies to disrupt the reinforced networks, an approach being explored by Mayo’s BIONIC initiative.

AI Detects Hidden Brain Lesions to Improve Childhood Epilepsy Treatment
health9 months ago

AI Detects Hidden Brain Lesions to Improve Childhood Epilepsy Treatment

An AI tool developed by researchers at Murdoch Children's Research Institute and The Royal Children's Hospital has significantly improved the detection of tiny brain lesions in children with epilepsy, leading to targeted surgeries that have successfully made some children, like John, seizure-free. The AI, called 'AI epilepsy detective,' enhances MRI and PET scan analysis, allowing for earlier and more precise treatment, which can prevent long-term learning difficulties associated with uncontrolled seizures.

Neuronal Synchronization in Memory Formation and Recall
science11 months ago

Neuronal Synchronization in Memory Formation and Recall

Researchers studying epilepsy patients found that nerve cells in the medial temporal lobe synchronize their firing with slow brain waves, known as theta rhythms, during both learning and recall, suggesting this synchronization is a general feature of memory processing rather than a predictor of successful recall. The findings deepen understanding of brain rhythms in memory and could inform future treatments for memory disorders.