Thiamine Metabolism May Influence How Often You Poop
Genetic analyses of over 260,000 people and UK Biobank data link vitamin B1 (thiamine) metabolism to gut motility and stool frequency, suggesting thiamine intake could affect constipation or diarrhea in some individuals. The findings identify two gene variants influencing thiamine activation/transport and point to specific biological pathways for future lab and clinical studies, with potential for personalized nutrition approaches in managing gut-motility disorders.
