Tag

Methionine

All articles tagged with #methionine

Longevity diet linked to higher GLP-1 and leaner bodies, study finds
health7 days ago

Longevity diet linked to higher GLP-1 and leaner bodies, study finds

A Mediterranean-inspired “longevity diet” that is low in amino acids but includes methionine supplementation and higher carbohydrate and fat content boosted GLP-1, reduced fat mass and frailty, and improved cardiometabolic markers in mice. The approach is based on methionine intake from foods like eggs, fish, nuts and seeds; human data from over 200,000 people suggest plant-based, low‑amino‑acid patterns may support healthy aging, though higher animal-protein intake is linked to healthier lifestyles but greater risk of diabetes and obesity. While methionine can aid frailty reduction, the diet isn’t a magic bullet but could be a promising strategy for aging healthfully.

Methionine-tuned plant diet extends healthspan in mice, with potential human implications
science27 days ago

Methionine-tuned plant diet extends healthspan in mice, with potential human implications

USC researchers show that a low-protein, plant-forward longevity diet supplemented with a small amount of methionine (LDMM) improves healthspan and reduces fat and frailty in aged mice; analyses of over 200,000 humans link higher animal-protein/methionine intake to obesity and diabetes, suggesting that a largely vegan/vegetarian diet with fish—and balanced methionine—may optimize healthy aging. Too little or too much methionine dampens benefits, highlighting amino-acid composition as a key lever. Next steps include human trials; findings involve disclosures of interests and funding.

Dietary methionine may steer disease outcomes by boosting kidney clearance and reducing inflammation
science4 months ago

Dietary methionine may steer disease outcomes by boosting kidney clearance and reducing inflammation

Salk Institute researchers found that methionine supplementation in infected mice boosted kidney filtration, lowered circulating cytokines, and improved blood flow, shifting disease trajectories away from inflammation-related damage toward recovery—protecting against wasting, blood-brain barrier disruption, sepsis, and death. The effect did not impair immune response, but human efficacy remains untested and further studies are needed to translate this to clinical use, including for kidney disease or dialysis patients.

Low Methionine and Cysteine Diet Sparks Fat Burning in Mice
health-and-medicine4 months ago

Low Methionine and Cysteine Diet Sparks Fat Burning in Mice

Reducing two amino acids common in animal protein—methionine and cysteine—in mice boosted energy expenditure by about 20% via beige fat, causing weight loss without changing food intake or activity, and was comparable to constant cold exposure, suggesting diet alone could activate fat-burning pathways, though human relevance remains unproven and further work on safety and applicability is needed.

Methionine may blunt severe illness in animal tests, study suggests
health5 months ago

Methionine may blunt severe illness in animal tests, study suggests

New animal research indicates the essential amino acid methionine, when added to the diet, can protect against severe illness by dampening inflammation and improving kidney function in mice with infection-induced inflammation. The study found methionine boosted kidney filtration and reduced inflammatory damage without weakening the immune response. While researchers see potential for broader use in inflammatory diseases, results are early and human relevance is not yet established, warranting further investigation.