Tag

Multiple Myeloma

All articles tagged with #multiple myeloma

world1 hour ago•1 min saved

Pope Leo XIV's Brother Louis Prevost Enters Cancer Clinical Trial Amid Pontiff's Lung Diagnosis

Pope Leo XIV's older brother, Louis Prevost, is currently undergoing a clinical trial for multiple myeloma, his wife told CBS News. This development follows the Vatican's announcement that the 71-year-old pontiff was diagnosed with lung cancer after surgery to remove part of his right lung. While the Vatican withheld details on the pope's cancer stage, Louis's wife, Deborah Prevost, indicated her husband's condition had recently worsened after years of remission. The family is supporting both brothers through their respective medical treatments.

via CBS News|

#catholic-church #louis-prevost #multiple-myeloma

entertainment13 days ago•5 min saved

Lady A's Charles Kelley Diagnosed with Multiple Myeloma, Vows to Continue Touring

Country music star Charles Kelley, co-lead vocalist of the Grammy-winning trio Lady A, has been diagnosed with multiple myeloma, a rare blood cancer. The 45-year-old musician revealed the news on Instagram on September 29, 2026, alongside his wife, Cassie. Kelley explained that the diagnosis was discovered after doctors ordered blood tests to investigate unexplained rib fractures. Despite the serious diagnosis, Kelley expressed optimism, citing advancements in treatment and improved life expectancy. He stated his intention to continue working and performing, including upcoming Christmas shows, while undergoing treatment. His bandmates, Hillary Scott and Dave Haywood, publicly expressed support for him and his family.

via BBC|

#charles-kelley #country-music #entertainment

entertainment14 days ago•4 min saved

Lady A's Charles Kelley Diagnosed with Multiple Myeloma After Rib Fractures

Country music star Charles Kelley, co-lead vocalist of the trio Lady A, has been diagnosed with multiple myeloma, a rare blood cancer. He revealed the news on September 29, 2026, via an Instagram video posted alongside his wife, Cassie. The diagnosis was discovered after doctors ordered blood tests to investigate unexplained rib fractures. Kelley expressed optimism, noting that modern treatments have improved life expectancy, and stated his intention to continue performing and working through the first six months of treatment.

via Fox News|

#charles-kelley #country-music #entertainment

entertainment14 days ago•1 min saved

Country Star Charles Kelley Announces Multiple Myeloma Diagnosis, Vows to Continue Touring

Charles Kelley, co-lead vocalist of the country trio Lady A, has been diagnosed with multiple myeloma, a rare blood cancer. He revealed the news on Instagram on September 29, 2026, alongside his wife, Cassie McConnell Kelley. The diagnosis was discovered after doctors ordered blood tests to investigate unexplained rib fractures. Kelley expressed optimism, stating that modern treatments have improved life expectancy and that he intends to continue performing, including upcoming Christmas shows, while undergoing treatment.

via ABC News - Breaking News, Latest News and Videos|

#charles-kelley #country-music #entertainment

entertainment14 days ago•19 min saved

Lady A’s Charles Kelley Diagnosed with Multiple Myeloma After Rib Fracture Scare

Country singer Charles Kelley, 45, has been diagnosed with multiple myeloma, a rare blood cancer affecting plasma cells in the bone marrow. The diagnosis was discovered after routine blood tests were ordered to investigate unexplained rib fractures. Kelley announced the news via Instagram on September 29, 2026, alongside his wife, Cassie McConnell. He expressed optimism, noting that modern treatments have significantly improved life expectancy and that he intends to continue performing with his band, Lady A, while managing the condition.

via Page Six|

#charles-kelley #country-music #entertainment

cellgene-tx1 month ago•2 min saved

BMS claims Phase 2 success for GPRC5D-directed CAR-T in myeloma

Bristol Myers Squibb claims Phase 2 success for a GPRC5D-targeted CAR-T therapy in multiple myeloma, underscoring the potential of this target while noting ongoing questions about durability and outcomes after progression.

via Endpoints News|

#bristol-myers-squibb #car-t #cellgene-tx

science1 month ago•44 min saved

Single-cell atlas redefines myeloma archetypes and proliferative states, guiding prognosis and FCRL2-targeted therapy

Researchers built a population-scale single-cell atlas of 341 multiple myeloma patients, identifying five malignant transcriptional archetypes and a proliferative program tied to genomic features and clinical outcomes; validated in the CoMMpass cohort, the dataset enables dual-layer patient stratification and target nomination, notably highlighting FCRL2 as a plasma-cell–restricted target whose CAR-T cells show antigen-specific activity in vitro and survival benefit in vivo, informing precision therapy for plasma-cell malignancies.

via Nature|

#fcrl2 #intratumor-heterogeneity #multiple-myeloma

health2 months ago•2 min saved

FDA approves Zenbexus, first-in-class therapy for advanced multiple myeloma

The FDA approved Bristol Myers Squibb's oral iberdomide (Zenbexus) for advanced multiple myeloma in combination with Darzalex and dexamethasone, marking the debut of a new drug class and the use of a more sensitive measure of cancer remission.

via statnews.com|

#fda-approval #health #iberdomide

entertainment2 months ago•4 min saved

Patti Scialfa's Cancer Is In Remission, Springsteen Says

Bruce Springsteen announced in a video at the Pan-Mass Challenge that Patti Scialfa, his wife and longtime E Street Band member, is in remission from multiple myeloma, marking a hopeful turn in her battle with cancer that became public in 2018.

via Los Angeles Times|

#bruce-springsteen #entertainment #multiple-myeloma

entertainment2 months ago•4 min saved

Springsteen Reveals Patti Scialfa's Myeloma Is in Remission

Bruce Springsteen announced that Patti Scialfa's blood cancer, multiple myeloma, is in remission and shared the update during a Pan-Mass Challenge fundraiser, praising her strength, the support of her medical team at Dana-Farber, and the importance of ongoing cancer research.

via USA Today|

#bruce-springsteen #entertainment #multiple-myeloma

health3 months ago•3 min saved

Sanofi wins FDA nod for subcutaneous Sarclisa with on-body injector

The FDA approved Sanofi’s Sarclisa Escena, a subcutaneous version of Sarclisa that can be delivered by hand or Enable Injections’ CirCLIQ on-body injector, marking the first subcutaneous anticancer therapy usable with an OBI. In a phase 3 trial in relapsed/refractory multiple myeloma after at least one prior line, Sarclisa Escena plus pomalidomide and dexamethasone achieved an objective response rate of 71.1%—non-inferior to 70.5% with the IV Sarclisa–pomalidomide–dexamethasone regimen—while reducing administration time. The device’s rollout positions Sanofi to better compete with Johnson & Johnson’s Darzalex Faspro. Europe had already cleared OBIs for Sarclisa, and J&J highlighted Darzalex’ broader indications and established, monthly dosing in its own subcutaneous form.

via Fierce Pharma|

#darzalex-competition #fda-approval #health

health3 months ago•5 min saved

J&J CEO projects cancer elimination within a decade through immunotherapy breakthroughs

At the WSJ Leadership Institute summit, Johnson & Johnson CEO Joaquin Duato said the company aims to eliminate cancer within 10 years, citing breakthroughs in immunotherapy that have extended remission in multiple myeloma and improved longevity, with AI and biomarkers enabling earlier diagnosis and more personalized treatments. He suggested some cancers could be cured while others become chronic, and noted J&J's acquisitions like Firefly Bio to target difficult mutations, alongside advances such as a melanoma vaccine study by Merck and Moderna that underscores rapid progress in oncology.

via Fox News|

#cancer-cure-timeline #cancer-research #health

health4 months ago•17 min saved

One-time CAR-T therapy Carvykti reshapes myeloma care and biotech leadership

Multiple myeloma, a brutal blood cancer, is increasingly treatable thanks to CAR-T immunotherapy, especially Carvykti, a BCMA-targeting one-time infusion that has produced durable remissions and in some cases cures. Developed in China and licensed to a Western company, Carvykti’s success—with CARTITUDE-1 showing a 76% response rate and five-year data indicating about 33% disease-free—highlights a shift in biotech leadership from the US to China, driven by faster early-stage trials and regulatory reforms. The US still dominates late-stage development, but China’s rapid trial ecosystem is accelerating the global pipeline, potentially enabling earlier, even first-line, use of such therapies and signaling a broad realignment in drug discovery and approval.

via Works in Progress Magazine|

#bcma #biotech-regulatory-reform #car-t-therapy

healthcare4 months ago•3 min saved

Lilly-backed in vivo CAR-T delivers durable MRD-negativity in multiple myeloma

Kelonia Therapeutics’ KLN-1010, an off-the-shelf in vivo CAR-T for BCMA in relapsed/refractory multiple myeloma, produced MRD-negativity in all 18 treated patients at one month, with all assessable patients remaining MRD-negative at six months and the longest follow-up over 10 months. The safety profile is favorable (mostly grade 1–2 CRS and two ICANS cases). Lilly’s $3.2 billion deal for Kelonia could accelerate moving KLN-1010 into earlier lines and set the stage for phase 3 trials and broader in vivo CAR-T applications across cancer types.

via Fierce Biotech|

#healthcare #in-vivo-car-t #kelonia

health6 months ago•35 min saved

60-year-old dad plans his funeral after acid reflux misdiagnosis uncovers cancer

A 60-year-old man from Newcastle, Ian Swindell, was repeatedly diagnosed with acid reflux for months before a bone marrow biopsy revealed incurable multiple myeloma. He underwent emergency radiotherapy and chemotherapy, now relies on a walking stick and wheelchair, and is planning his own funeral to ease the burden on his kids, while urging others to seek second opinions when something feels wrong and to listen to their bodies.

via Yahoo|

#acid-reflux #cancer #health