tldrdailynews.com logo
Tag

Pediatric

All articles tagged with #pediatric

Ontario boy’s fatal rabies case linked to bat exposure highlights risk and delays in treatment
health17 days ago

Ontario boy’s fatal rabies case linked to bat exposure highlights risk and delays in treatment

An 11-year-old in Ontario died from rabies after waking to find a bat on his face during a 2024 cottage stay. The bat was removed outside, and the family did not seek immediate medical care, despite guidance to evaluate any direct bat contact for possible rabies. Weeks later he developed facial swelling and paralysis, was misdiagnosed with herpes and Bell’s palsy, and his condition rapidly worsened until he died 17 days after hospital admission. Rabies is almost always fatal once symptoms appear but preventable with timely postexposure treatment; human rabies is rare in Canada and the U.S., and this was Ontario’s first case since 1967.

via NBC News|
#bat-exposure#health#infectious-disease
Ontario boy dies from rabies after bat exposure at cottage
health18 days ago

Ontario boy dies from rabies after bat exposure at cottage

An 11-year-old boy in Ontario, Canada died from rabies after a bat landed on his face at a northern Ontario cottage about 19 days before symptoms. Initial medical visits yielded misdiagnoses (Bell's palsy and a severe oral infection) before rabies was suspected and confirmed on day four; he deteriorated with autonomic dysfunction and progressive neurologic decline and died after 17 days in intensive care.

via Euronews.com|
#bat#canada#health
Ontario boy dies of rabies after bat contact, prompting warning on urgent post-exposure care
health19 days ago

Ontario boy dies of rabies after bat contact, prompting warning on urgent post-exposure care

An 11-year-old in northern Ontario woke to a bat on his face and, despite no visible bite, later died from rabies—the first locally acquired human case in Ontario since 1967. The case highlights the importance of seeking immediate medical evaluation after any direct bat contact, since rabies is almost always fatal once symptoms appear, though prompt post‑exposure treatment can prevent infection.

via USA Today|
#bat-exposure#case-report#health
Ontario Bat Exposure Tragedy: 11-Year-Old Dies of Rabies
health19 days ago

Ontario Bat Exposure Tragedy: 11-Year-Old Dies of Rabies

An 11-year-old Canadian boy died from rabies after awakening with a bat on his mouth during a 2024 cottage visit in northern Ontario. The bat was captured and released, and no bite marks were observed, so his parents did not seek medical care. Nineteen days later he developed facial numbness and other symptoms, was initially misdiagnosed with herpes, and rapidly deteriorated until a rabies diagnosis was confirmed by PCR on day four of hospitalization; the bat rabies virus variant was identified later. He died on the 17th day in hospital. The case underscores that any direct contact with a bat is high risk, that rabies is almost always fatal once symptoms appear, and that prompt post-exposure prophylaxis can prevent infection.

via East Idaho News|
#bat#canada#health
Bat encounter ends in tragedy as Canadian boy dies of rabies
health19 days ago

Bat encounter ends in tragedy as Canadian boy dies of rabies

An 11-year-old Canadian boy died from rabies after waking to a bat on his nose and mouth during a cottage visit in Ontario in 2024. Because there were no visible bites and the bat’s behavior seemed normal, his parents did not seek medical care; 19 days later he developed progressive neurological symptoms and was misdiagnosed with herpes-related illness before rabies was confirmed by PCR. He died 17 days after hospital admission. Rabies remains a fatal disease once symptoms appear, but prompt post-exposure prophylaxis can prevent infection. Ontario has not recorded a locally acquired human rabies case since 1967, underscoring the ongoing public-health guidance to seek medical advice after potential bat exposure and keep pets vaccinated.

via CNN|
#bat#canada#health
Texas teen endures triple amputations after severe flu complications
health20 days ago

Texas teen endures triple amputations after severe flu complications

A 14-year-old girl from Kerrville, Texas, diagnosed with the flu, developed life-threatening bacterial infections (strep pneumonia and sepsis) that progressed to necrotizing pneumonia and multi-organ failure. After a 117-day hospitalization, she underwent amputation of her right arm and both legs, now uses prosthetics and requires inpatient rehab; a GoFundMe was launched to cover medical bills, prosthetics, and home modifications.

via New York Post|
#amputation#flu#health
Toddler's brain tumor stirs caution over gene-therapy viruses
health2 months ago

Toddler's brain tumor stirs caution over gene-therapy viruses

After a failed stem-cell transplant, a 13-month-old boy received a novel gene-therapy treatment and initially made progress, but a routine scan later revealed a golf-ball-sized brain tumor; scientists say the tumor may be linked to the gene-therapy viruses, highlighting the need to weigh life-saving benefits against rare but serious risks in such approaches.

via statnews.com|
#biotechnology#brain-tumor#gene-therapy
Teen Survives Rare Hantavirus with ECMO: A Doctor's Inside Look
health2 months ago

Teen Survives Rare Hantavirus with ECMO: A Doctor's Inside Look

An ICU doctor at Cincinnati Children’s Hospital details the rare hantavirus case of a 14-year-old patient who deteriorated rapidly, requiring intubation and five days on ECMO, a life-saving but high-risk heart–lung bypass. With no antiviral cure, treatment is supportive, and diagnosis is challenging because hantavirus is rare in Ohio and testing isn’t always rapid. Evie recovered after a month in hospital thanks to access to an ECMO-capable center and a skilled team, illustrating why quick transfer to such facilities is crucial and highlighting the ongoing need for research into therapies for this deadly disease.

via Women's Health|
#critical-care#cruise-ship#ecmo
Colorado records eighth pediatric flu death as season proves deadly for children
health2 months ago

Colorado records eighth pediatric flu death as season proves deadly for children

Colorado has reported its eighth pediatric influenza death this season, the most in more than two decades aside from the 2009 H1N1 pandemic; five of the eight deaths were unvaccinated, with others lacking vaccination records. Officials say the season is severe and emphasize that flu vaccines offer protection, noting pediatric vaccination rates are similar to last year though rural areas lag. The flu can cause severe illness requiring ICU care, and nationwide pediatric flu deaths total 149 this season; vaccine uptake remains a challenge in younger adults and in several rural counties.

via Colorado Public Radio|
#colorado#health#influenza
FDA Grants Accelerated Approval for KRESLADI to Treat Pediatric LAD-I
healthcare3 months ago

FDA Grants Accelerated Approval for KRESLADI to Treat Pediatric LAD-I

Rocket Pharmaceuticals announced that the FDA granted accelerated approval for KRESLADI (marnetegragene autotemcel), an autologous hematopoietic stem cell–based gene therapy for pediatric patients with severe LAD-I due to ITGB2 variants who lack an HLA-matched donor. Approval is based on increased neutrophil CD18/CD11a expression and will rely on longer-term follow-up data and a post‑marketing registry to confirm benefit. The FDA also awarded Rocket a Rare Pediatric Disease Priority Review Voucher, which the company plans to monetize. LAD-I is ultra-rare and causes recurrent life-threatening infections; safety concerns include infections during conditioning, veno-occlusive disease, engraftment failure, potential insertional oncogenesis, hypersensitivity, anti-retroviral interactions, and possible HIV test false positives, necessitating long-term monitoring. A conference call is planned for March 27, 2026.

via Business Wire|
#fda-approval#gene-therapy#healthcare
FDA Clears First Gene Therapy for Severe LAD-I in Children
health3 months ago

FDA Clears First Gene Therapy for Severe LAD-I in Children

The FDA approved Kresladi (marnetegragene autotemcel), the first gene therapy for severe Leukocyte Adhesion Deficiency Type I in pediatric patients without an HLA-matched donor, using autologous gene-modified stem cells to restore ITGB2 function and CD18/CD11a on white blood cells. The treatment is given as a single IV infusion after conditioning, based on biomarker improvements in an open-label trial, with post-marketing confirmatory studies required and safety monitoring for cytopenias and infections.

via fda.gov|
#fda-accelerated-approval#gene-therapy#health
Texas teen loses three limbs after flu-triggered pneumonia complications
health4 months ago

Texas teen loses three limbs after flu-triggered pneumonia complications

A 13-year-old Kerrville, Texas, girl named Kaydin Ruiz developed life-threatening flu complications when influenza led to a severe strep pneumonia infection that caused clotting and organ failure, resulting in the amputation of three limbs; she remains hospitalized at Texas Children’s Hospital as her family raises awareness of flu risks and doctors urge vaccination to prevent such severe outcomes.

via Daily Mail|
#amputation#flu#health
New drug brings life-changing relief to children with Dravet syndrome
health4 months ago

New drug brings life-changing relief to children with Dravet syndrome

A new drug, zorevunersen, delivered by spinal infusion, is showing strong promise for Dravet syndrome in children by boosting brain sodium channel activity and dramatically reducing seizures; early trials report up to 90% fewer seizures, with patients like Freddie Truelove moving from hundreds of daily seizures to a few per week and regaining normal activities. UK and US trials involve young children, starting from age two, at several hospitals, and while results are encouraging, Phase 3 data are needed before it becomes widely available.

via BBC|
#clinical-trial#dravet-syndrome#epilepsy