Tag

Psoriatic Arthritis

All articles tagged with #psoriatic arthritis

health2 hours ago•2 min saved

MoonLake's nanobody delivers strong phase 3 results in psoriatic arthritis

MoonLake Immunotherapeutics reported positive topline phase 3 IZAR-1 data for biologic‑naïve psoriatic arthritis patients treated with sonelokimab, with week‑16 endpoints meeting across ACR50 (42.1%), ACR20 (66.5%), minimal disease activity (41.2%), and PASI90 in patients with skin involvement (61%), though there is no active comparator arm and topline results will be followed by blinded analyses with full data due in H1 2027; IZAR-2 and other IL-17 nanobody programs are ongoing.

via Fierce Biotech|

#health #moonlake-immunotherapeutics #nanobody

health6 months ago•6 min saved

Skin Immune Cells Trigger Hidden Psoriatic Arthritis

Researchers found that immune cells formed in inflamed psoriasis skin can migrate into the bloodstream and travel to joints, where they encounter fibroblasts and ignite inflammation leading to psoriatic arthritis. The study explains why only some psoriasis patients develop arthritis and suggests blood-d detectable migratory cells could serve as an early warning, with future therapies aiming to intercept these cells before joint damage occurs.

via SciTechDaily|

#fibroblasts #health #immune-cells

healthcare7 months ago•1 min saved

Eli Lilly's Zepbound and Taltz Combo Shows Promise for Psoriatic Arthritis and Obesity

Eli Lilly's drug Zepbound, when combined with its immunology therapy Taltz, showed promise in reducing symptoms of psoriatic arthritis in obese patients, suggesting potential new uses for the weight loss drug, though its impact on prescribing patterns remains uncertain.

via statnews.com|

#eli-lilly #healthcare #immunology

health7 months ago•18 min saved

Lilly's Zepbound and Taltz Combo Shows Promise for Psoriatic Arthritis and Obesity

Eli Lilly's Phase 3b trial shows that combining Taltz (ixekizumab) and Zepbound (tirzepatide) significantly improves outcomes in adults with psoriatic arthritis and obesity, meeting primary and secondary efficacy endpoints and suggesting a potential new integrated treatment approach.

via Eli Lilly|

#clinical-trial #health #obesity

health2 years ago•4 min saved

"Breakthrough Gene Discovery Offers Hope for Psoriasis Patients"

Researchers at The Australian National University have discovered a gene mutation, IKBKB, responsible for causing psoriasis and potentially leading to psoriatic arthritis. The mutation affects the function of immune cells, contributing to inflammation and disease onset. The findings offer hope for improved diagnosis and treatment, potentially leading to a cure for the conditions, which affect hundreds of thousands of Australians. Patients hope to break the stigma associated with these conditions and raise awareness of the challenges they face.

via Medical Xpress|

#autoimmune-disease #gene-discovery #health

health2 years ago•8 min saved

"Unhealed: The Painful Saga of a Swollen Ankle"

After rolling her ankle, Catherine Matacic suffered from increasingly severe ankle pain for eight years, seeking treatment from multiple doctors and physical therapists without success. In January 2023, a rheumatologist diagnosed her with psoriatic arthritis, a chronic autoimmune disease, after suspecting it due to her age, activity level, and MRI results. Despite initial skepticism, genetic testing confirmed the diagnosis, and medication has significantly improved her ability to walk without pain. Matacic wishes she had taken her pain more seriously and consulted doctors sooner, emphasizing the importance of respecting injuries.

via The Washington Post|

#ankle-pain #delayed-diagnosis #health

health2 years ago•8 min saved

The Link Between a Common Skin Condition and Joint/Heart Health

Psoriasis, a common skin condition, is not only associated with painful joints due to psoriatic arthritis but also raises the risk of heart disease. Many patients are unaware of these secondary implications and are not receiving the necessary regular checks to monitor their joint and heart health. Psoriasis patients should undergo annual reviews to check for psoriatic arthritis and be assessed for cardiovascular disease. Early screening and monitoring can help control risk factors and improve outcomes. Treatment options for psoriasis have improved, including the use of biologics, which have shown effectiveness in reducing symptoms. However, care for psoriasis patients varies across the country, and there is a need for increased awareness and attention to potential associated conditions.

via Daily Mail|

#health #heart-disease #inflammation

health3 years ago•3 min saved

Advancing Skin Health: Experts Call for Consensus Human Skin Cell Atlas

In August 2023, experts at the Asembia Specialty Pharmacy Summit emphasized the importance of listening to patients and caregivers when treating pediatric atopic dermatitis (AD), a skin condition characterized by inflamed and itchy rashes. Sleep disturbances and anxiety are common among caregivers, highlighting the need for comprehensive care. Meanwhile, a study found that upadacitinib maintained its efficacy for 3 years in patients with psoriatic arthritis, with no new safety concerns identified. Additionally, lebrikizumab showed promising results in improving or clearing the skin of adult and adolescent patients with moderate to severe AD.

via Pharmacy Times|

#health #lebrikizumab #pediatric-atopic-dermatitis

health3 years ago•4 min saved

Kathy Griffin's Easter MRI amidst health concerns and cancer battle.

Comedian and actress Kathy Griffin spent part of her Easter holiday undergoing an MRI, following a series of health concerns, including a lung cancer diagnosis in August 2021 that resulted in an operation to remove half of her left lung. Griffin has also undergone vocal cord surgery and treatment for psoriatic arthritis. Celebrities have shown their support for Griffin on social media.

via Daily Mail|

#health #kathy-griffin #lung-cancer