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Rentosertib

All articles tagged with #rentosertib

AI-designed lung drug hints at aging slowdown in IPF study
health1 hour ago

AI-designed lung drug hints at aging slowdown in IPF study

A small 12-week trial of rentosertib, an AI-discovered drug for IPF, found blood protein changes and aging biomarkers that made participants appear biologically 3–4 years younger, strongest after four weeks at 30 mg twice daily; the results, published in Nature Biotechnology, are preliminary, based on 42 IPF patients, and do not prove real aging reversal. Larger, longer trials including non-IPF populations are needed; a Phase 3 study is underway in China.

AI-Designed Drug Hints at Slowing Aging
science1 day ago

AI-Designed Drug Hints at Slowing Aging

Insilico Medicine used generative artificial intelligence to design rentosertib, a small-molecule drug for a chronic lung condition. New clinical-trial data reported in Nature Biotechnology indicate the AI-designed drug reduced biological aging markers across six aging clocks, suggesting a potential to slow aging—but further research is needed to confirm safety, efficacy, and applicability beyond the lung disease context.