A 17-year-old Fall River resident, Broeden Sabin, has been battling fatigue and pain and is seeking a bone marrow donor while undergoing a blood transplant this month, as his family appeals for potential donors.
Fred Hutch researchers produced fully human monoclonal antibodies against EBV by targeting its gp350 and gp42 proteins. In humanized mice, one antibody completely prevented EBV infection and another offered partial protection, outlining a pathway to prevent EBV reactivation and PTLD in transplant patients. The team aims to advance safety testing in healthy volunteers followed by trials in immunocompromised individuals, with IP protection filed for the antibodies.
A Florida construction project manager in his early 30s blamed fatigue and weight gain on aging and new fatherhood, but after his symptoms worsened he was diagnosed with left ventricular non-compaction cardiomyopathy (LVNC) and a genetic muscle disorder, leading to advanced heart failure. He underwent a left ventricular assist device (LVAD) implantation to sustain circulation while awaiting a heart transplant, highlighting a rising trend of heart failure in younger adults driven by obesity, diabetes, and high blood pressure.
Faye Greenwood, a Lewes-based influencer, experienced a heart attack at age 24 while on holiday in Paris, leading to a heart transplant and raising awareness about heart health in young adults. She and her fiancé, also an influencer, shared their story to highlight the importance of recognizing symptoms early, despite misconceptions about age and heart risks. The couple faced significant medical bills and uncertainty about her future career, emphasizing the need for awareness and prompt medical attention for heart issues in young people.
A 13-year-old girl with heart conditions was added to Cincinnati Children's transplant list after initially being refused due to her unvaccinated status, amid family and public pressure, including a letter from Donald Trump, challenging hospital vaccination policies.
A 13-year-old girl with heart conditions was initially denied a transplant due to her unvaccinated status, but her doctors waived the policy; her family supports a bill in Ohio to prevent hospitals from denying transplants based on religious or vaccine objections.
Nick Mangold, a former Jets center and seven-time Pro Bowler, is suffering from chronic kidney disease and is seeking a kidney donor with type O blood, reaching out to fans for help through a donation website.
Canadian researchers have discovered a microRNA, miR-423-5p, that can protect kidney blood vessels after injury and serve as a blood-based biomarker for early detection and treatment of chronic kidney disease, with potential applications in transplantation and other vascular-related conditions.
Chinese scientists have successfully transplanted human stem cell-derived dopamine-producing neurons into mice, reducing depressive behaviors and increasing pleasure, offering potential new treatments for neuropsychiatric disorders like major depressive disorder.
A man with type 1 diabetes has successfully produced his own insulin after receiving genetically engineered, CRISPR-edited cell transplants that evade immune rejection, marking a potential breakthrough in diabetes treatment.
A man with type 1 diabetes received genetically modified pancreatic cells via CRISPR that allowed his body to produce insulin without needing lifelong immunosuppressant drugs, marking a significant step toward a potential cure for the disease.
A man with type 1 diabetes successfully received gene-edited pancreatic cells that produce insulin without the need for immunosuppressive drugs, demonstrating a promising advance in transplantation medicine and potential future cure for diabetes.
A 13-year-old boy with a rare genetic condition called Danon disease, which affects only about 300 families worldwide, was diagnosed with severe heart failure and required a heart transplant. His mother, who also has the disease, and he are among the few documented African-American cases. The story highlights the importance of support systems for young transplant patients, leading to the creation of a virtual community called Transplant Teenz to help teenagers cope with their condition.
Janine Roberson, who was diagnosed with Type 1 diabetes at age 7 and suffered from severe complications, has successfully undergone a kidney-pancreas transplant, leading to a cure for her diabetes and a significant improvement in her quality of life. She recently graduated from El Camino College with an associate degree, overcoming numerous challenges including dialysis and the loss of her father, and plans to pursue a career helping children with chronic illnesses.
Curtis Jackson, a healthy man, was diagnosed with a rare and deadly liver cancer called cholangiocarcinoma during routine screenings after an initial diagnosis of primary sclerosing cholangitis. Early detection allowed for successful treatment with surgery and chemotherapy, highlighting the importance of regular health screenings for early diagnosis of serious diseases.