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Transplant

All articles tagged with #transplant

Antibody Breakthrough Blocks Epstein-Barr Virus in Mice, Could Aid Transplant Patients
science29 days ago

Antibody Breakthrough Blocks Epstein-Barr Virus in Mice, Could Aid Transplant Patients

Epstein-Barr virus (EBV) infects about 95% of adults and can persist for life, with links to cancers and other complications. A team from Fred Hutchinson Cancer Center and the University of Washington developed human-like antibodies targeting EBV surface proteins gp350 and gp42, isolating 10 candidates. In mice with humanized immune systems, one antibody provided protection against EBV, demonstrating a new approach to prevent infection and reactivation. The work could help immunosuppressed transplant patients by reducing EBV-related complications (PTLD), but human safety testing and clinical trials are still needed. Published in Cell Reports Medicine (2026).

via ScienceAlert|
#antibodies#epstein-barr-virus#gp350
Will Self on Death, Morality, and a Life Rewritten by Illness
culture1 month ago

Will Self on Death, Morality, and a Life Rewritten by Illness

An intimate Observer profile in which Will Self discusses his battle with myelofibrosis and a stem-cell transplant, steroid-induced lows, and past addiction, alongside a lifelong literary project—from his early bravado to The Quantity Theory of Morality. He reflects on the Deborah Orr divorce, public perception, and his ambitious plan for ethics-centered works like Mortal Morality, arguing for a rethinking of morality in a digitized society while facing mortality with lucid, often defiant candor.

via The Observer|
#culture#illness#literature
Antibody Strategy Targets Epstein-Barr Virus to Shield Transplant Patients
science3 months ago

Antibody Strategy Targets Epstein-Barr Virus to Shield Transplant Patients

Fred Hutch researchers produced fully human monoclonal antibodies against EBV by targeting its gp350 and gp42 proteins. In humanized mice, one antibody completely prevented EBV infection and another offered partial protection, outlining a pathway to prevent EBV reactivation and PTLD in transplant patients. The team aims to advance safety testing in healthy volunteers followed by trials in immunocompromised individuals, with IP protection filed for the antibodies.

via SciTechDaily|
#epstein-barr-virus#gp350#gp42
Fatigue Mistaken for Aging Uncovered Rare Heart Condition in a Young Dad
health3 months ago

Fatigue Mistaken for Aging Uncovered Rare Heart Condition in a Young Dad

A Florida construction project manager in his early 30s blamed fatigue and weight gain on aging and new fatherhood, but after his symptoms worsened he was diagnosed with left ventricular non-compaction cardiomyopathy (LVNC) and a genetic muscle disorder, leading to advanced heart failure. He underwent a left ventricular assist device (LVAD) implantation to sustain circulation while awaiting a heart transplant, highlighting a rising trend of heart failure in younger adults driven by obesity, diabetes, and high blood pressure.

via dailymail.co.uk|
#cardiology#health#heart-failure
Lewes Influencer Shares Heart Transplant Journey at 24
health4 months ago

Lewes Influencer Shares Heart Transplant Journey at 24

Faye Greenwood, a Lewes-based influencer, experienced a heart attack at age 24 while on holiday in Paris, leading to a heart transplant and raising awareness about heart health in young adults. She and her fiancé, also an influencer, shared their story to highlight the importance of recognizing symptoms early, despite misconceptions about age and heart risks. The couple faced significant medical bills and uncertainty about her future career, emphasizing the need for awareness and prompt medical attention for heart issues in young people.

via BBC|
#health#heartattack#influencer
13-Year-Old's Chest Pain Reveals Rare Near-Death Heart Condition
health10 months ago

13-Year-Old's Chest Pain Reveals Rare Near-Death Heart Condition

A 13-year-old boy with a rare genetic condition called Danon disease, which affects only about 300 families worldwide, was diagnosed with severe heart failure and required a heart transplant. His mother, who also has the disease, and he are among the few documented African-American cases. The story highlights the importance of support systems for young transplant patients, leading to the creation of a virtual community called Transplant Teenz to help teenagers cope with their condition.

via CBS News|
#danon-disease#health#heart-disease