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Antibodies

All articles tagged with #antibodies

Georgia Woman Is First in State to Survive Heart Failure with HALT Procedure
health1 day ago

Georgia Woman Is First in State to Survive Heart Failure with HALT Procedure

Monica McFarlan, diagnosed with heart failure at 37, endured 15 years of LVADs and life-threatening complications and was deemed ineligible for a traditional heart transplant due to high antibody levels. She became the first in Georgia to receive the groundbreaking Heart-After-Liver Transplant (HALT), a 16-hour procedure that first replaces the liver to reset the immune system before a heart transplant, bypassing the antibody barrier and giving her a new chance at life.

via AOL.com|
#antibodies#halt#health
Georgia Woman Becomes State’s First HALT Transplant Recipient, Saving Her Failing Heart
health1 day ago

Georgia Woman Becomes State’s First HALT Transplant Recipient, Saving Her Failing Heart

Monica McFarlan, diagnosed with heart failure at 37, endured years of surgeries and LVADs and was deemed ineligible for a traditional heart transplant due to high antibodies. In a groundbreaking 16-hour Heart-After-Liver Transplant (HALT), doctors first transplant a liver to reset her immune system, then perform the heart transplant, making her the first patient in Georgia to receive this treatment and giving her a life-saving second chance while she remains on lifelong immunosuppression.

via Yahoo News Canada|
#antibodies#georgia#halt
Tick-Borne Antibody Signals Higher Red Meat Allergy Risk Than Expected
health9 days ago

Tick-Borne Antibody Signals Higher Red Meat Allergy Risk Than Expected

A CDC analysis of 3,000 adults across 10 states found about 24% in five states with high lone star tick activity have antibodies to alpha-gal, indicating prior tick bites and potential risk for alpha-gal syndrome (a red meat allergy). Antibodies show exposure, not disease, so not everyone will develop symptoms. The true prevalence is uncertain, and cases are not nationally notifiable; ticks and affected areas may expand as deer move and winters warm. Symptoms typically appear hours after eating red meat, and the condition is lifelong once developed.

via NBC News|
#alpha-gal-syndrome#antibodies#health
Widespread image manipulation flagged in Thermo Fisher antibody catalog
science1 month ago

Widespread image manipulation flagged in Thermo Fisher antibody catalog

Researchers documented 127 problematic images in Thermo Fisher's antibody catalogue, finding more than 100 manipulated images—ranging from duplicated western blot bands to painted backgrounds and identical blot backdrops. The findings contribute to ongoing concerns about the reliability of commercial antibodies; Thermo Fisher says it is conducting an internal review and will inform users when images have been optimized for presentation.

via Nature|
#antibodies#image-manipulation#science
Lab-made antibodies offer potential post-exposure measles therapy
science2 months ago

Lab-made antibodies offer potential post-exposure measles therapy

Scientists isolated four potent monoclonal antibodies from a vaccinated donor’s blood that block measles by targeting the virus’s H and F proteins. In rodent tests, these antibodies reduced lung virus after exposure, suggesting potential post-exposure or preventive use, though they are not a substitute for vaccination and delivery challenges remain. Further testing is needed before any human therapy.

via The Washington Post|
#antibodies#measles#monoclonal-antibodies
Antibody Breakthrough Blocks Epstein-Barr Virus in Mice, Could Aid Transplant Patients
science2 months ago

Antibody Breakthrough Blocks Epstein-Barr Virus in Mice, Could Aid Transplant Patients

Epstein-Barr virus (EBV) infects about 95% of adults and can persist for life, with links to cancers and other complications. A team from Fred Hutchinson Cancer Center and the University of Washington developed human-like antibodies targeting EBV surface proteins gp350 and gp42, isolating 10 candidates. In mice with humanized immune systems, one antibody provided protection against EBV, demonstrating a new approach to prevent infection and reactivation. The work could help immunosuppressed transplant patients by reducing EBV-related complications (PTLD), but human safety testing and clinical trials are still needed. Published in Cell Reports Medicine (2026).

via ScienceAlert|
#antibodies#epstein-barr-virus#gp350
Why the Rare Vaccine-Linked Clots Happen, Explained
science4 months ago

Why the Rare Vaccine-Linked Clots Happen, Explained

An international study of 100 VITT patients shows the condition starts with antibodies that target an adenovirus protein; a single antibody mutation then makes them bind platelet factor 4 strongly, and a common immune gene variant shapes the response. VITT requires both a hereditary variant and a rare antibody mutation, explaining its rarity and offering clues for designing safer adenovirus-based vaccines in the future.

via ScienceAlert|
#adenovirus#antibodies#platelet-factor-4
Camelid Antibodies Offer New Hope for Alzheimer's Treatment
health8 months ago

Camelid Antibodies Offer New Hope for Alzheimer's Treatment

A new study suggests that nanobodies, small antibody-like proteins found in camelids like alpacas, could be developed into treatments for brain disorders such as Alzheimer's, offering potential advantages over traditional antibodies due to their size and ability to passively enter the brain, though further safety and efficacy testing is needed before clinical trials.

via Good News Network|
#alzheimers#antibodies#brain-disorders
mRNA HIV Vaccine Shows Promising Early Results in Fight Against Virus
health11 months ago

mRNA HIV Vaccine Shows Promising Early Results in Fight Against Virus

A small trial using mRNA technology, similar to COVID-19 vaccines, has shown promising results in producing potent, virus-blocking antibodies against HIV, especially when the vaccine encodes a membrane-anchored version of the virus's outer protein, marking a significant breakthrough in HIV vaccine development. However, challenges remain in ensuring broad protection and safety.

via ZME Science|
#antibodies#clinical-trial#health