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Embryos

All articles tagged with #embryos

Embryo base editing nudges germline research toward reality, intensifying designer-baby debate
science2 days ago

Embryo base editing nudges germline research toward reality, intensifying designer-baby debate

New studies using base editing in early human embryos show precision editing with fewer chromosomal errors but still face mosaicism and off-target effects. While these results advance understanding of embryo development and disease-related genes, experts warn that safety, ethical, and regulatory hurdles remain, keeping the door to germline editing and “designer babies” firmly closed for now rather than opened.

via CNN|
#base-editing#crispr#embryos
Autophagy Failure in Older Eggs Halts Early Embryo Development
science26 days ago

Autophagy Failure in Older Eggs Halts Early Embryo Development

Researchers find that aging in female eggs dampens embryonic autophagy, causing ACOX1 buildup and hyperactive fatty-acid oxidation that drains NAD+, prevents erasure of histone H3K9ac, and blocks exit from minor zygotic genome activation, leading to early developmental arrest. Activating autophagy with Rapamycin rescues development in aged embryos, and the mechanism is conserved in human eggs, suggesting metabolic interventions could boost IVF success for older women.

via Neuroscience News|
#acox1#autophagy#beta-oxidation
science1 month ago

China Tests Artificial Embryos in Space to Probe Gravity's Role in Early Development

China's Academy of Sciences is sending artificial human embryo models to the Tiangong space station to study how early development unfolds in microgravity. Representing roughly two- and three-week stages, the samples will be frozen after five days for analysis on orbit and on Earth, aiming to compare space- and Earth-based development and gauge gravity's influence, while noting ethical constraints and potential future countermeasures; the rise of private spaceflight raises questions about potential similar experiments by civilians.

via extremetech.com|
#biology#china#embryos
Khloé Kardashian Secures Tristan Thompson's Embryos and Keeps His Sperm Banked
celebrity1 month ago

Khloé Kardashian Secures Tristan Thompson's Embryos and Keeps His Sperm Banked

Khloé Kardashian reveals on The Cut that Tristan Thompson signed over some of his frozen embryos to her after he had a vasectomy, effectively giving her ownership of his sperm; Thompson says he's done having kids unless they're from Kardashian's embryos, while Kardashian notes she’s preserving sperm for a future possibility, and the couple share two children, True and Tatum.

via The Cut|
#celebrity#embryos#khloe-kardashian
Khloé Kardashian Reveals Tristan Thompson’s Vasectomy After Her Ultimatum
entertainment1 month ago

Khloé Kardashian Reveals Tristan Thompson’s Vasectomy After Her Ultimatum

On her Khloé in Wonder Land podcast, Khloé Kardashian says she persuaded ex Tristan Thompson to get a vasectomy; she also reveals she signed over the rights to their embryos and kept a contingency plan to preserve sperm for a future partner, noting any future kids would have to come from her embryos, while they remain seamless co-parents.

via HuffPost|
#embryos#entertainment#kardashians
Khloé Kardashian's Ultimatum Sparks Tristan Thompson's Vasectomy Revelation
entertainment1 month ago

Khloé Kardashian's Ultimatum Sparks Tristan Thompson's Vasectomy Revelation

Tristan Thompson revealed on Khloé Kardashian’s Khloé in Wonder Land podcast that he had a vasectomy after Khloé gave him an ultimatum about expanding their family. The discussion touches on future kids, with Tristan joking that any additional children would have to come from Khloé’s embryos, and Khloé confirming she kept some of his sperm for a potential future scenario. Thompson is already father to four children (a 9-year-old son with Jordan Craig, an 8-year-old daughter and a 3-year-old son with Khloé, and a 4-year-old with Maralee Nichols), and he says he doesn’t want more kids unless it’s via Khloé’s embryos.

via BuzzFeed|
#embryos#entertainment#khloe-kardashian
Oldest Amniote Embryos Hint Early Reptiles Gave Birth Alive
science1 month ago

Oldest Amniote Embryos Hint Early Reptiles Gave Birth Alive

Brazilian and Uruguayan fossils from the Early Permian reveal 280-million-year-old mesosaur embryos preserved inside adults and an isolated egg, suggesting mesosaurs may have retained embryos in the uterus or laid eggs at late development; this finding pushes the oldest known amniote embryos and earliest viviparity back by about 60 million years, offering rare insights into reproduction and potential parental care in Paleozoic reptiles.

via The Daily Galaxy|
#amniotes#embryos#mesosaurs
Biotech Start-Up Claims Lab-Grown Sperm Could Help Infertile Men (Awaiting Validation)
biotech2 months ago

Biotech Start-Up Claims Lab-Grown Sperm Could Help Infertile Men (Awaiting Validation)

Utah-based Paterna Biosciences says it has found a way to coax sperm-forming stem cells from testicular tissue to become mature, functional sperm in a lab and used this sperm to create embryos; the work has not yet been peer-reviewed or independently verified, and the company plans larger studies to compare lab-made and natural sperm in men with infertility before attempting pregnancies; if validated, the approach could offer a biological option for some infertile men, but questions of cost and safety remain.

via WIRED|
#biotech#biotech-startup#embryos
Space reproduction hurdles: microgravity slows sperm and embryo development
space-exploration3 months ago

Space reproduction hurdles: microgravity slows sperm and embryo development

A University of Adelaide study used a 3D clinostat to simulate microgravity and found that sperm from humans, mice, and pigs had about 30% fewer chances to reach eggs in microgravity, while embryos formed under these conditions initially appeared stronger but degraded with longer exposure. The results suggest mammalian reproduction in space could be highly challenging for long-term space settlements, though future work could explore partial gravity (Moon/Mars) and potential IVF advances on Earth.

via Space|
#embryos#ivf#microgravity
China's 200+ Pterosaur Eggs Hint at Early Flight Development
science4 months ago

China's 200+ Pterosaur Eggs Hint at Early Flight Development

In northwestern China, researchers uncovered more than 200 fossilized eggs from the flying reptile Hamipterus tianshanensis in a single sandstone block, including at least 16 embryos preserved in three dimensions. Dated to about 120 million years ago in the early Cretaceous, the find provides one of the largest pterosaur egg collections and suggests rapid burial by floodwaters aided preservation. CT scans indicate that some embryos lacked fully developed wing structures while the femur was well developed, implying hatchlings might have been flightless; however, researchers caution against over-interpretation. The discovery greatly expands sample size for studying egg and embryo variation and the origins of flight in pterosaurs.

via The Daily Galaxy|
#cretaceous#embryos#fossil-eggs
Oldest Mesosaur Embryos Hint at Early Live Birth in Reptiles
science4 months ago

Oldest Mesosaur Embryos Hint at Early Live Birth in Reptiles

Researchers report 280-million-year-old mesosaur embryos from Brazil and Uruguay, providing the oldest direct evidence that these ancient aquatic reptiles could give birth to live young, pushing the origin of viviparity back about 60 million years; findings also indicate potential parental care, with some fossils suggesting a mixed strategy where at least one egg was found at an advanced stage of development.

via The Daily Galaxy|
#embryos#mesosaurs#paleontology