All articles tagged with #glioblastoma
Jason Collins, the NBA’s first openly gay player, died at 47 from Stage 4 glioblastoma. After his diagnosis he sought experimental treatment in Singapore to extend his life, returned to the U.S. and continued public appearances as his cancer progressed, and died at home in Los Angeles. A 13-season NBA veteran, he came out in 2013, briefly joined the Nets in 2014 on a 10-day contract, and retired later that year.
Jason Collins, the NBA’s first openly gay player, died at 47 after an eight-month battle with glioblastoma brain cancer; over 13 seasons and six teams he helped the Nets reach two Finals and, after coming out in 2013, became a leading advocate for LGBTQ inclusion in sport and a longtime NBA Cares Ambassador.
A phase 1 trial of GNOS-PV01, a personalized DNA vaccine for unmethylated MGMT glioblastoma, is safe and elicits broad immune responses by targeting up to 40 patient-specific neoantigens, transforming the tumor microenvironment from cold to hot and reducing the likelihood of tumor escape; results show two-thirds progression-free at six months and two-thirds overall survival at one year, with one patient recurrence-free nearly five years post-diagnosis, supporting larger trials and expansion to all GBM types.
Jason Collins, the NBA’s first openly gay player, died at age 47 after months of treatment for glioblastoma; his 2013 coming-out and advocacy helped push inclusivity in basketball and professional sports, drawing tributes from across the league and beyond.
A phase 1 trial at Siteman Cancer Center shows a personalized neoantigen DNA vaccine (GNOS-PV01) for glioblastoma is safe and elicits robust immune responses; among nine patients, about two-thirds had no progression at six months and two-thirds were alive at one year, including a long-term recurrence-free survivor, indicating potential benefit and the need for larger trials.
Jason Collins, the NBA's first openly gay active player, died at 47 following a battle with glioblastoma brain cancer. A 7-foot center who played 13 seasons and helped the Nets reach the 2002-03 Finals, Collins publicly came out in 2013, becoming a symbol of inclusion in sport; his family and peers praised his lasting impact and legacy.
Jason Collins, the NBA's first openly gay player, died at 47 after a valiant battle with Stage 4 glioblastoma. The former Nets center played 13 NBA seasons with the Nets, Grizzlies, Timberwolves, Hawks, Celtics and Wizards, publicly revealed his brain cancer in December, pursued experimental treatment in Singapore, and remained an inspirational advocate for inclusivity in sports.
Jason Collins, a 13-year NBA veteran and NBA Cares ambassador who helped break barriers for LGBTQ athletes, died at 47 after a valiant battle with glioblastoma. NBA Commissioner Adam Silver and the Collins family issued statements praising his leadership, inclusivity, and impact beyond basketball, including his life with husband Brunson.
A Nature News & Views piece describes Koeber et al.'s strategy to selectively kill glioblastoma cells by using a virus to deliver an engineered DNA sequence that encodes a protein needed for a drug to kill the tumor, plus a cytokine to rally the immune system; in mice, this viral cargo eliminated brain tumours, offering a potential targeted cancer therapy that aims to spare healthy tissue.
A team created synthetic super-enhancers by assembling natural enhancer fragments bound by SOX2 and SOX9 in glioblastoma stem cells to achieve high, selective transgene expression. They packaged these SSEs into AAV vectors to drive a dual payload (HSV-TK/GCV cytotoxic system and IL-12) in a mouse glioblastoma model, achieving tumor clearance and immunological memory; SSE activity was validated in primary human GSCs and brain tissue slices, suggesting SSEs could enable cell-state-specific, potent gene therapy with broad applicability.
University of Calgary researchers are testing high-dose vitamin B3 (niacin) in addition to standard glioblastoma treatment. Early Phase I/II results in 24 patients show 82% progression-free at six months, a 28% improvement over historical data, suggesting niacin may restore immune function to attack tumors. Safety monitoring remains essential, and enrollment will expand to 48 participants by 2026–2027 to confirm benefits.
Mission Viejo couple Zak and Cori Salazar, both diagnosed with cancer in 2023, face ongoing battles—Zak with glioblastoma and Cori with pancreatic cancer—while raising three young daughters; they lean on grief-aware parenting, death-doula guidance, and a daily commitment to living fully, even as a scare over a brain MRI led to halting Zak's chemo after it proved to be a false alarm.
A phase 1 trial in 41 patients with recurrent glioblastoma found that a single injection of a modified herpes simplex virus can kill tumor cells and recruit enduring T cell activity into the tumor, correlating with longer survival than historical outcomes.
A 23-year-old medical student from Liverpool endured years of stroke-like episodes doctors dismissed as stress or health anxiety; after an emergency brain surgery in 2025, he was diagnosed with glioblastoma, an incurable brain cancer. Despite the delayed diagnosis, he underwent tumor removal and chemo/radiation; cancer later spread, and he is now traveling to Germany for cutting-edge immunotherapy while urging earlier scans for others with similar symptoms.
A 23-year-old medical student endured years of stroke-like episodes and fatigue that doctors repeatedly attributed to stress or health anxiety, with his father saying they visited about 50 doctors. A May 2025 episode led to emergency brain surgery that uncovered a 5 cm glioblastoma; prognosis is poor (12–18 months). He’s undergoing chemotherapy and radiation and is traveling to Germany for cutting-edge immunotherapy, as his family urges clinicians to take persistent symptoms in young people more seriously and push for earlier scans.