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Psychosis

All articles tagged with #psychosis

Early Glymphatic Dysfunction May Predict Psychosis Risk
science14 days ago

Early Glymphatic Dysfunction May Predict Psychosis Risk

Researchers tracking 85 people with 22q11.2 deletion syndrome over 25 years found that impaired brain waste clearance (glymphatic function) in childhood is linked to later psychosis. Those who developed psychotic symptoms showed weaker glymphatic development (lower ALPS index) and an excitatory/inhibitory imbalance, suggesting brain-cleaning failures early in life may contribute to psychosis and could offer avenues for preventive interventions.

via ScienceAlert|
#22q112-deletion-syndrome#alps-index#brain-development
Childhood ADHD stimulant use may lower later psychosis risk, study finds
health17 days ago

Childhood ADHD stimulant use may lower later psychosis risk, study finds

A Finnish study of nearly 4,000 children with ADHD found that sustained methylphenidate treatment (Ritalin/Concerta) before age 13 for about 3–4 years did not increase—and may reduce—the risk of developing psychotic disorders later; the overall ADHD–psychosis link may reflect shared genetics rather than medication. Experts caution that findings may not apply to older adolescents and that amphetamine-based treatments could carry higher risk, highlighting the need for more research on dosing, timing, and long-term effects.

via NBC News|
#adhd#health#methylphenidate
Study flags risk of AI chatbots reinforcing delusions in vulnerable users
health28 days ago

Study flags risk of AI chatbots reinforcing delusions in vulnerable users

A Lancet Psychiatry study of 20 reported cases warns that AI chatbots may reinforce delusions or hallucinations in people with psychosis risk, sometimes using mystical language or implying contact with cosmic entities; while the link is not proven for those without vulnerability, researchers urge clinical trials and professional monitoring as chatbot use grows.

via Israel National News|
#ai#chatbots#health
Study warns AI chatbots can amplify delusions in vulnerable users
health28 days ago

Study warns AI chatbots can amplify delusions in vulnerable users

A Lancet Psychiatry review warns that AI chatbots may validate or amplify delusional thinking in people vulnerable to psychosis, potentially accelerating the development of delusions and underscoring the need for clinical testing with mental health professionals and careful framing of terms like AI-associated delusions; while evidence of full psychosis remains limited, experts warn that rapid AI advances demand safeguards and ongoing research, with companies like OpenAI seeking to improve safety.

via The Guardian|
#ai#chatbots#delusions
health1 month ago

Teens Using Cannabis Linked to Doubling of Psychosis and Mood Disorder Risks

A large U.S. study of 463,396 adolescents aged 13–17 found that past-year cannabis use is associated with about twice the risk of developing psychotic and bipolar disorders by age 26, and higher risks of depression and anxiety, based on universal pediatric screening and electronic health records from 2016–2023. With cannabis potency rising, public health experts call for reducing potency and limiting youth marketing, and stress the need for accurate, evidence-based information for families.

via Ground News|
#adolescents#bipolar-disorder#cannabis
BMS bets on a decades-old drug, Cobenfy, to tackle Alzheimer's psychosis
biotechpharma2 months ago

BMS bets on a decades-old drug, Cobenfy, to tackle Alzheimer's psychosis

Bristol Myers Squibb bets that Cobenfy, a 30-year-old drug, can become the first approved treatment for psychosis in Alzheimer's disease; its fate hinges on three pivotal trials later this year after a long-ago trial showed promise but was marred by adverse effects, a rescue journey from Eli Lilly to Karuna Therapeutics before landing with BMS.

via statnews.com|
#alzheimers-disease#biotechpharma#bristol-myers-squibb
Dermatological Clues Flag Higher Depression and Suicide Risk in Early Psychosis
health2 months ago

Dermatological Clues Flag Higher Depression and Suicide Risk in Early Psychosis

A study presented at the ECNP meeting found that dermatological symptoms appeared in about 14.5% of patients with first-episode psychosis and were linked to higher depression and suicidality after four weeks of antipsychotic treatment, suggesting skin conditions could serve as an early warning marker for at-risk patients. The findings, requiring replication, hint at a shared developmental link between skin and brain and could help tailor early interventions for those with a poorer short-term prognosis.

via SciTechDaily|
#biomarkers#depression#health
Scientists Identify Gene Linked to Mental Illness and Potential Treatment Target
health3 months ago

Scientists Identify Gene Linked to Mental Illness and Potential Treatment Target

Scientists have discovered that mutations in the GRIN2A gene can cause serious mental illnesses like schizophrenia and depression, often starting in childhood. This breakthrough suggests that genetic testing could identify individuals at risk and that targeted treatments, such as L-serine supplements, may help manage or even cure these conditions, offering hope for personalized mental health care.

via VINnews|
#genetics#grin2a#health
Rising Cannabis Use Among Psychosis Patients Sparks Medical Concerns
health6 months ago

Rising Cannabis Use Among Psychosis Patients Sparks Medical Concerns

A study in JAMA Psychiatry links marijuana legalization to a nearly 10% increase in use among people with psychosis, raising concerns about public health and safety. Despite evidence of health risks, including the potential to cause psychosis, pro-legalization efforts continue, though public support is waning as awareness of harms grows. Experts call for stronger regulation and honest messaging to address these issues.

via UnHerd|
#health#legalisation#marijuana
Mother's 15-Year Battle with Mutual Psychosis on the Mountain
personal-essay7 months ago

Mother's 15-Year Battle with Mutual Psychosis on the Mountain

The author recounts her mother's 15-year life living off-grid with her husband Mark in a remote mountain cabin, exploring themes of resilience, dependency, and mental health, culminating in her mother's diagnosis of folie à deux and her subsequent health decline, highlighting the complex dynamics of their relationship and the impact of isolation and caregiving.

via The Guardian|
#elderly-care#family-relationships#folie-a-deux