Tag

Observational Study

All articles tagged with #observational study

medical-research12 hours ago•12 min saved

US switch to recombinant shingles vaccine linked to lower cardiovascular risk

A Nature Medicine study using US electronic health record data finds that older adults vaccinated predominantly with the recombinant shingles vaccine exhibit a lower cardiovascular disease burden over seven years, with reduced risks for heart failure and ischemic heart disease, and a modest, sex-specific reduction in ischemic stroke; though associations persist across analyses, causality cannot be established and effects may wane over time.

via News-Medical|

#cardiovascular-disease #medical-research #nature-medicine

health1 day ago•81 min saved

High-Dose Vitamin D Linked to 4-Point Boost on Brain Test in Early Cognitive Decline

A small observational study of 54 adults with mild cognitive impairment and sleep disturbances found that those taking 5,000+ IU of vitamin D daily scored about four points higher on cognitive testing (Montreal Cognitive Assessment) than peers not taking the supplement; lower doses showed only nominal gains and results were not always statistically significant. The finding held regardless of vitamin D form (D2 or D3). Researchers caution that this shows association, not causation, and call for clinical trials to determine whether vitamin D supplementation can meaningfully improve cognition in people with early cognitive changes. The Mayo Clinic notes a typical recommended daily intake of 600–800 IU (under age 70) and an upper limit of 4,000 IU.

via inc.com|

#brain-health #cognitive-decline #health

health1 day ago•6 min saved

Shingrix linked to lower dementia risk in older adults, study suggests

A Brown University study of more than 509,000 adults aged 66+ found that those who had at least one Shingrix dose showed a 24% relative reduction in dementia diagnoses over four years versus unvaccinated peers, based on electronic health records and Medicare data; researchers stress this is an association, not proof of causation, and the vaccine’s primary purpose is shingles prevention, though explanations include fewer shingles-related complications and potential vascular benefits. The study was funded by GSK.

via Fox News|

#dementia-risk #health #observational-study

science1 day ago•22 min saved

Shingrix Could Protect the Heart for Years, Study Suggests

A US study of about 70,000 adults aged 60+ found that the recombinant shingles vaccine Shingrix is associated with a lower risk of cardiovascular disease years after vaccination compared with the older live vaccine, with the strongest effect on ischemic heart disease and heart failure; the finding hints at immune-system changes beyond shingles, though the observational design aims to reduce bias by comparing groups who chose vaccination rather than vaccinated versus unvaccinated.

via ZME Science|

#cardiovascular-disease #immune-system #observational-study

health9 days ago•6 min saved

First and Last Meal Timing Tied to Longevity in Large Study

In a large US study of 31,044 adults followed for about 8.6 years, later first-meal timing (especially after noon) and later last meals were linked to higher all-cause and cardiovascular mortality, with the lowest risk around an 8 pm last meal; however, the findings are observational and could reflect underlying health, routines, or other factors, so they do not prove that changing meal times will extend life.

via ScienceAlert|

#circadian-rhythm #health #meal-timing

health9 days ago•3 min saved

Sugary drinks daily linked to almost triple stomach cancer risk, study shows

Researchers analyzing data from more than 100,000 participants in two long-running cohorts found that consuming at least one sugary drink daily was linked to nearly a threefold increase in gastric (stomach) cancer risk, while artificially sweetened beverages showed no such association. The study, which adjusts for other risk factors, shows an association—not causation—and the mostly white healthcare-professional sample limits generalizability; further research is needed to confirm findings in diverse populations and to clarify the role of fructose.

via LiveNOW from FOX|

#fructose #health #helicobacter-pylori

health15 days ago•55 min saved

Wine Linked to Lower Death Risk in Large UK Study

In data from more than 340,000 UK Biobank participants (2006–2022), wine at low to moderate levels was associated with lower all-cause and cardiovascular mortality, while beer and spirits were linked to higher death risk. High overall alcohol consumption raised all-cause mortality by 24%, and the type of beverage mattered for lower risk. The authors note that this is observational and may reflect healthier lifestyles among wine drinkers, so causality cannot be established; randomized trials are needed for confirmation.

via Yahoo|

#alcohol-consumption #cardiovascular-death #health

health16 days ago•6 min saved

Greener neighborhoods linked to lower diabetes risk, study suggests

A UK Biobank analysis of over 400,000 participants followed for about 15 years finds that greater access to green space—especially private gardens within 100 meters and four or more nearby parks—is associated with a modestly lower risk of developing type 2 diabetes, while distance to parks mattered little; the study is observational and cannot establish causation, but it underscores potential public-health and urban-planning benefits of green spaces.

via ScienceAlert|

#diabetes #green-space #health

health20 days ago•2 min saved

Denosumab May Shield Joints in Osteoporosis Patients

Using Japanese claims data (2015–2024), new denosumab users had a 16% lower 3-year risk of developing osteoarthritis vs new oral bisphosphonate users (relative risk 0.84; 95% CI 0.73–0.89), especially for knee and hip OA. The benefit was not significant for those who switched from bisphosphonates to denosumab. Given the observational design and potential confounding, findings should be interpreted with caution and require clinically validated OA outcomes.

via Medscape|

#bisphosphonates #denosumab #health

health25 days ago•6 min saved

GLP-1 Weight-Loss Drugs Show Potential to Lower Breast Cancer Recurrence

Observational findings presented at ASCO 2026 suggest GLP-1 medications (e.g., Ozempic, Wegovy) may be linked to lower breast cancer recurrence and possibly prevention, likely via weight loss and reduced inflammation; however, the evidence is not causative and randomized controlled trials are needed, with clinicians cautioning patients not to rely on GLP-1s solely for cancer risk reduction until proven.

via Fox News|

#breast-cancer #glp-1-drugs #health

health1 month ago•9 min saved

Plant-forward Diet May Shield Older Women's Heart Health

A 20-year study of 66,892 initially cardio‑disease-free postmenopausal women found that higher adherence to the Planetary Health Diet was linked to lower risks of overall cardiovascular disease, coronary heart disease, stroke, and heart failure, with about a 28% risk reduction in the highest-adherence group and benefits seen even with moderate adherence. The diet emphasizes fruits, vegetables, whole grains, legumes, nuts, and unsaturated fats while limiting red/processed meats, added sugars, refined grains, and saturated fats. While observational and not causative, the findings suggest that gradual, realistic shifts toward plant-forward eating—such as filling half the plate with vegetables, using healthier fats, and trying meatless meals—could benefit heart health in aging women.

via News-Medical|

#cardiovascular-disease #diet-quality #health

health2 months ago•5 min saved

Six Months of Breastfeeding May Lower Kids' ADHD Risk, Study Finds

A Norwegian study of about 37,600 families found that longer exclusive breastfeeding up to six months is linked to lower ADHD symptom levels at ages 3, 5 and 8, seen in both boys and girls and remaining after adjusting for genetics and sociodemographic factors; while the association persists, researchers caution that causality can't be proven and the sample isn't fully representative, so more research is needed, though findings echo guidelines that support exclusive breastfeeding for about six months.

via New York Post|

#adhd #breastfeeding #health

health2 months ago•4 min saved

VA data suggest COVID boosters curb heart risk in older veterans

A study using US Veterans Affairs records found the 2024-2025 COVID vaccine, given with the flu vaccine on the same day, was associated with lower risk of COVID-related major adverse cardiovascular events (MACE) in more than one million veterans, particularly those 75 and older and with underlying conditions. Within eight months, relative vaccine effectiveness was 37.7% for all MACE, including a 57.9% lower risk of cardiovascular death, 38.5% lower risk of heart attack, and 41.9% lower risk of hospitalization for heart failure; stroke reduction was not statistically significant. The study is observational and cannot prove causation, and declines in COVID testing and infection severity may affect the links observed.

via New York Post|

#cardiovascular-events #covid-vaccine #health

health2 months ago•6 min saved

Anti-inflammatory Diet Linked to Lower Dementia Risk in Alzheimer’s Pathology

In a 15-year observational study of 1,865 older adults, researchers found that diets with lower inflammatory potential were associated with a 21–29% reduced dementia risk among those with elevated Alzheimer’s biomarkers; the Mediterranean-style diet showed benefits mainly in people with lower biomarker levels. While the study cannot prove causation, it supports the idea that high‑quality, anti‑inflammatory eating patterns—rich in vegetables, fruits, nuts, whole grains, and healthy fats, with limited processed foods and sugary drinks—may promote brain health and delay dementia onset.

via Medical News Today|

#alzheimer-biomarkers #anti-inflammatory-diet #brain-health

health2 months ago•6 min saved

Switching to Vapes May Raise Eye Disease Risk, Major Study Finds

A large Korean study of 32,316 matched former smokers followed for about 4.6 years found that those who switched to electronic cigarettes or other smokeless nicotine products had a higher risk of major eye diseases than those who quit nicotine entirely. Specifically, switchers had a 24% higher risk of diabetic retinopathy and a 7% higher risk of refractive/accommodation disorders, with quitters showing 41.1 vs 44 cases per 1,000 person-years. The study observed 6,328 eye-disease events overall. Authors caution that the retrospective, self-reported data cannot prove causation, but the findings suggest substituting nicotine products may not eliminate eye-disease risk.

via Fox News|

#diabetic-retinopathy #eye-health #health