
New Enzyme ArmA Redefines Archaeal Cell Wall Structure
Researchers have identified ArmA, a new enzyme from the gut methanogen Methanobrevibacter smithii, which acts as the first specific hydrolase for archaeal peptidoglycan. By digesting this cell wall component, scientists revealed a previously unknown structure involving a novel sugar called N-acetylarmosamine. This discovery overturns a 50-year-old model of archaeal cell walls and provides a critical tool for studying methanogen biology, similar to how muramidases are used for bacteria.













