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Brain Atlas

All articles tagged with #brain atlas

New Atlas Maps Gene Activity in Prefrontal Cortex Across Lifespan
science17 days ago

New Atlas Maps Gene Activity in Prefrontal Cortex Across Lifespan

Researchers have created the most comprehensive map of gene activity in the human prefrontal cortex, utilizing data from nearly 1,500 donors. This landmark atlas, which tracks gene expression from infancy to old age, provides critical insights into the biological mechanisms underlying neurodegenerative and psychiatric disorders, potentially accelerating the development of targeted therapies for conditions like Alzheimer's disease and schizophrenia.

via Nature|
#alzheimers-disease#brain-atlas#genomics
3D lamprey brain atlas maps ancient vertebrate brain evolution
science3 months ago

3D lamprey brain atlas maps ancient vertebrate brain evolution

Chinese researchers have built the first 3D spatial single-cell atlas of the lamprey brain, enabling reconstruction of ancestral vertebrate brain features and revealing conserved gene expression and neurogenesis patterns with mammals; published as a Science cover article on June 19, 2026, the work suggests early vertebrate brains were already well-partitioned and provides a new resource for brain-evolution studies.

via Global Times|
#brain-atlas#lamprey#science
Sex-Specific GLP-1 Brain Map Could Explain Weight-Loss Drug Differences
science7 months ago

Sex-Specific GLP-1 Brain Map Could Explain Weight-Loss Drug Differences

Researchers used RNAscope to build the first sex-specific atlas of GLP-1 expression in the mouse brain, mapping GLP-1 across 25 brain nuclei in three female and three male mice. They found notable sex differences: females have higher GLP-1 density in hindbrain appetite regions (ROb, SolV, SolM), while males show higher GLP-1 in the olfactory bulb, with some regions showing female-only (ventral tegmental area) or male-only (lateral hypothalamus) expression. The atlas helps explain why women often lose more weight on GLP-1 drugs like semaglutide and suggests potential sex-specific avenues for treating addiction, depression, and cognitive decline, though limitations include the small sample size and the fact that transcript presence does not prove peptide release or function.

via Neuroscience News|
#brain-atlas#glp-1#obesity
Unveiling the Unprecedented Detail of the Human Brain: A Revolutionary Brain Cell Atlas
science-and-technology3 years ago

Unveiling the Unprecedented Detail of the Human Brain: A Revolutionary Brain Cell Atlas

Scientists have created the largest and most detailed atlas of the human brain, revealing the arrangement and inner workings of 3,300 types of brain cells, many of which were previously unknown. The research, part of the BRAIN Initiative Cell Census Network, used cutting-edge techniques to map the cells found in the brains of humans, mice, and nonhuman primates. The atlas provides insights into the similarities and differences between human and nonhuman primate brains, and opens up new possibilities for understanding neurological diseases and what makes us human.

via Livescience.com|
#brain-atlas#brain-research#cell-types
Mapping the Cuttlefish Brain for Instant Skin Color Changes.
science3 years ago

Mapping the Cuttlefish Brain for Instant Skin Color Changes.

A team of neuroscientists at Columbia's Zuckerman Institute has created a brain atlas of the dwarf cuttlefish, Sepia bandensis, depicting the brain's overall 32-lobed structure as well as its cellular organization. The atlas will help researchers understand how the cuttlefish achieves its astonishing feat of camouflage. The team used magnetic resonance imaging (MRI) and histological techniques to create the atlas, which is available on the website Cuttlebase.org. The atlas offers cellular resolution and is equivalent to a detailed atlas that shows all of the roads, hills, lakes, and rivers of the states.

via Phys.org|
#artificial-intelligence#brain-atlas#camouflage