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Fruit Fly

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Fruit Fly Brain Connectome Lets a Brain Play Doom and Mario 64
technology1 month ago

Fruit Fly Brain Connectome Lets a Brain Play Doom and Mario 64

Researchers from Google and HHMI’s Janelia mapped the fruit fly’s nervous system into a connectome—the largest brain map by neuron count to date (about 166,000 neurons and 125 million synapses)—using serial EM and AI to reconstruct its wiring; the work aims to illuminate how brains perceive stimuli and repair neural pathways. Online developers are already using the data to train simulated fly brains to play Doom and Mario 64, with broader plans to map connectomes in other species.

via Gizmodo|
#connectome#doom#fruit-fly
Complete male fruit‑fly brain connectome enables direct male–female neural comparisons
science1 month ago

Complete male fruit‑fly brain connectome enables direct male–female neural comparisons

A newly completed map of the adult male fruit fly central nervous system catalogs about 166,000 neurons and the connections between them, enabling direct comparisons with the female brain (mapped to ~140,000 neurons in 2024). This connectome will help researchers understand how neural circuits drive sex-specific behaviors such as mating and aggression and serves as a technical roadmap for broader connectomics efforts in other species, including potential implications for human neuroscience.

via Live Science|
#brain-mapping#connectome#fruit-fly
Fruit Fly Connectome Reveals Distributed Brain-Body Control of Movement
science3 months ago

Fruit Fly Connectome Reveals Distributed Brain-Body Control of Movement

Researchers produced the first complete brain-to-body wiring map (connectome) for an adult fruit fly, revealing that many movements arise from local neural circuits in the brain and nerve cord rather than a single brain controller. The 3D map links brain and body connections, is openly accessible, and will enable new hypotheses in neuroscience and insights for AI—with the work published in Nature and expanding plans to add neuropeptide data.

via SciTechDaily|
#brain-body-integration#connectome#fruit-fly
technology7 months ago

Digital Fruit Fly Walks: Whole-Brain Emulation Drives a Virtual Body

Researchers demonstrated an embodied whole-brain emulation of an adult fruit fly using the FlyWire connectome, with 125,000 neurons and 50 million synapses driving walking and feeding in a simulated body powered by NeuroMechFly v2 and MuJoCo, achieving about 95% motor-prediction accuracy; the work uses a biological connectome replica rather than reinforcement learning and aims to scale to mice, advancing neuroscience and AI.

via Ground News|
#connectome#fruit-fly#mujoco
Unraveling Multisensory Integration in Navigation: A $6.5M NIH Grant Study
neuroscience3 years ago

Unraveling Multisensory Integration in Navigation: A $6.5M NIH Grant Study

Researchers have received a $6.5 million grant from the NIH to study how the fruit fly's brain integrates multisensory information during navigation, particularly when there are conflicts between sensors. By leveraging the fruit fly's complex behaviors and newly mapped connectomes, the study aims to shed light on human neurological functions. The research will investigate whether the flies prioritize certain sensors over others and how these prioritizations change in different environmental conditions. Collaborating with multiple institutions, the project will utilize advanced genetic techniques and state-of-the-art facilities to explore the brain's processing of multisensory information.

via Neuroscience News|
#brain-integration#fruit-fly#multisensory-information
Asian Fruit Fly Triggers Quarantine in Santa Clarita Valley
food-and-drink3 years ago

Asian Fruit Fly Triggers Quarantine in Santa Clarita Valley

A fruit fly native to Asia, known as the 'Tau' fruit fly, has led to a quarantine on produce in the Santa Clarita Valley in California. The 79-square-mile quarantine zone was implemented after over 20 of the invasive species were found in Stevenson Ranch. The 'Tau' fruit fly is a serious pest for important California crops such as avocado, cucurbits, citrus, tomatoes, and peppers. This is the first time such a quarantine has been imposed in the area, and growers have been instructed not to move any fruits and vegetables from their property.

via KABC-TV|
#california-crops#food-and-drink#fruit-fly
"Revolutionizing Neuroscience: A.I. Unveils Secrets of Brain Connections and Behavior"
science-and-technology3 years ago

"Revolutionizing Neuroscience: A.I. Unveils Secrets of Brain Connections and Behavior"

Scientists have used artificial intelligence (A.I.) to create the first whole-brain connectome, or neural pathway map, of a fruit fly's brain. This breakthrough in brain-mapping could revolutionize neuroscience and medicine by providing a comprehensive understanding of how neuron circuits process information. The A.I. model traced the connections between neurons in the fruit fly brain, significantly speeding up the process compared to manual tracing. While a whole-brain human connectome is still years away, the fruit fly connectome project demonstrates the potential for understanding neurodegenerative diseases and improving mental health treatment. The technology could also enable researchers to see how different parts of the brain communicate and develop hypotheses about diseases and dysfunctions more efficiently.

via Fortune|
#artificial-intelligence#brain-mapping#fruit-fly
New Fruit Fly Nerve Cord Connectome Revealed by Researchers
neuroscience3 years ago

New Fruit Fly Nerve Cord Connectome Revealed by Researchers

Researchers have released the most comprehensive connectome of the adult fruit fly nerve cord, providing an exceptional resource for the scientific community. The connectome, constructed from about 23,000 neurons, reveals the intricate network controlling the fly’s motor functions. New insights have already emerged from the data, challenging previous theories on fly movement. This achievement not only advances understanding of fruit fly neurology, but also serves as a model for similar future projects.

via Neuroscience News|
#connectome#fruit-fly#motor-functions
Discovery of a New Organelle in Well-Studied Organisms
science3 years ago

Discovery of a New Organelle in Well-Studied Organisms

Researchers at Rockefeller University have discovered a new organelle inside the gut cells of fruit flies that stores phosphate, an electrolyte essential to life. The organelle, called PXo bodies, releases its reservoir in the form of phospholipids, which are a key component of the membrane structure of cells. The discovery may lead to a search for phosphate-storing organelles in other animals, including humans, and further research may help us understand how the organelle fits into the life of the cell and how it changes over time.

via Freethink|
#cell-biology#fruit-fly#organelle