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Hearing Loss

All articles tagged with #hearing loss

Brain-Driven Hearing: Real-Time Focused Listening Using Neural Signals
science15 days ago

Brain-Driven Hearing: Real-Time Focused Listening Using Neural Signals

Columbia University researchers demonstrated the first real-time brain-controlled hearing system that uses implanted electrodes to detect which speaker a listener is focusing on and dynamically amplify that voice while quieting others, addressing the cocktail party problem. Tested in epilepsy patients, the system decoded attention from brain activity with machine-learning algorithms, improving speech intelligibility and reducing listening effort, and was consistently preferred by users. Published in Nature Neuroscience, this invasive approach paves the way for wearable, brain-sensing hearing aids that could someday operate in real-world noisy environments.

via Neuroscience News|
#brain-computer-interface#hearing-loss#neuroscience
FDA backs first gene therapy to treat a rare genetic deafness (Otarmeni) with free US access
health1 month ago

FDA backs first gene therapy to treat a rare genetic deafness (Otarmeni) with free US access

The FDA approved Otarmeni, Regeneron’s gene therapy for OTOF-related deafness—the first gene therapy for this rare inherited hearing loss—delivered via a single cochlear injection to restore otoferlin production. In a 20-child trial, several participants showed hearing improvements, with five of 12 followed for 11 months reaching near-normal hearing. Regeneron will provide Otarmeni at no cost to US patients, and the therapy was fast-tracked under the Commissioner’s National Priority Voucher program. While promising, effects were generally safe, the condition affects about 50 US babies born each year, and this advance could pave the way for more gene therapies and potentially reduce reliance on cochlear implants.

via New York Post|
#fda-approval#gene-therapy#health
FDA approves Otarmeni, first gene therapy for rare OTOF-related infant hearing loss
health1 month ago

FDA approves Otarmeni, first gene therapy for rare OTOF-related infant hearing loss

FDA approves Regeneron's Otarmeni, the first gene therapy for a rare OTOF-mutation–driven hearing loss in infants; in a trial, a single-dose inner-ear injection improved hearing in 16 of 20 children, with some able to detect whispers; the company will provide the drug for free to U.S. patients, while pricing outside the U.S. has not been determined since it is not approved there.

via NBC News|
#fda-approval#gene-therapy#health
FDA greenlights Otarmeni: first gene therapy to restore hearing in OTOF-related deafness, Regeneron to provide it free in the U.S.
healthcare1 month ago

FDA greenlights Otarmeni: first gene therapy to restore hearing in OTOF-related deafness, Regeneron to provide it free in the U.S.

The FDA granted accelerated approval for Otarmeni (lunsotogene parvec-cwha), a one-time gene therapy for severe-to-profound OTOF-related hearing loss, based on CHORD trial results showing 80% of participants reached a key hearing threshold at 24 weeks and 42% achieved normal hearing by 48 weeks; Regeneron will provide Otarmeni free to eligible U.S. patients as part of access programs, with continued confirmatory trials and safety monitoring ongoing.

via Regeneron|
#fda-accelerated-approval#gene-therapy#healthcare
Regeneron trims prices for some Americans and pledges free hearing-loss gene therapy after FDA nod
business1 month ago

Regeneron trims prices for some Americans and pledges free hearing-loss gene therapy after FDA nod

Regeneron said it will lower U.S. drug prices for some Americans under President Trump’s pricing plan and will offer its first hearing-loss gene therapy for free to eligible patients after regulatory approval, while also securing a three-year tariff exemption; the therapy Otarmeni targets a rare hearing-loss condition and could reduce reliance on cochlear implants, with analysts signaling potential peak sales around $130 million.

via CNBC|
#business#drug-pricing#gene-therapy
Treatable middle-ear problems tied to higher dementia risk, study suggests
health1 month ago

Treatable middle-ear problems tied to higher dementia risk, study suggests

A Columbia University study using NIH data from more than 300,000 U.S. adults found that two treatable middle-ear conditions—cholesteatoma and eardrum perforation—were linked with higher dementia odds (about 1.77x and over 2x, respectively), while otosclerosis showed no significant association; risk appeared to decrease somewhat with surgical treatment. The study is observational, indicating association rather than causation, and researchers note cognitive effects may be related to sensory deprivation from hearing loss.

via Fox News|
#cholesteatoma#dementia#eardrum-perforation
Decades of Dizziness Finally Revealed a Benign Acoustic Neuroma
health2 months ago

Decades of Dizziness Finally Revealed a Benign Acoustic Neuroma

A health writer recounts how her husband’s decades-long dizziness and unilateral hearing loss were repeatedly dismissed as stress until a CT scan revealed a four-centimeter acoustic neuroma, a typically slow-growing benign brain tumor. Surgery to remove it left him with left facial and throat paralysis, underscoring how earlier imaging and specialist input could have reduced harm and why persistent symptoms deserve thorough evaluation.

via SELF Magazine|
#acoustic-neuroma#delayed-diagnosis#dizziness
Hearing loss and dementia: a complex link, not a proven cause
health2 months ago

Hearing loss and dementia: a complex link, not a proven cause

Headlines that label hearing loss as the leading midlife dementia risk can be misleading. While hearing loss often coexists with cognitive decline, there’s no clear evidence that it directly causes dementia. The population-attributable-fraction metric depends on how common hearing loss is and its association with dementia, so individual risk remains modest. Hearing aids improve daily life and social connectedness, but evidence that they prevent dementia is limited, and most research comes from high‑income countries. More inclusive research is needed, but addressing hearing loss can support brain health and independence even if it doesn’t “cure” dementia.

via The Conversation|
#brain-health#dementia#health
Brain Changes Tie Hearing Loss to Dementia Risk, Study Finds
health3 months ago

Brain Changes Tie Hearing Loss to Dementia Risk, Study Finds

A new study links age-related hearing loss (presbycusis) to cognitive decline through coupled functional and structural brain changes. Researchers introduce the Functional-Structural Ratio (FSR), derived from MRI measures, which correlates with worse hearing and poorer cognitive performance in specific brain regions, suggesting FSR could serve as a biomarker for dementia risk. While cross-sectional, the findings highlight the potential of preserving hearing health to protect brain integrity and guide early interventions.

via Medical News Today|
#brain-imaging#cognitive-decline#functional-structural-ratio
Dementia Linked to Peripheral Health Issues, Not Just Brain Decline
health3 months ago

Dementia Linked to Peripheral Health Issues, Not Just Brain Decline

A global review of more than 200 studies finds up to one-third of dementia cases are linked to diseases outside the brain, with gum disease, chronic liver disease, hearing loss, vision loss, and type 2 diabetes showing the strongest associations. While causality isn’t proven, researchers say preventing peripheral diseases could help mitigate dementia risk and may explain why brain-focused treatments have often failed, highlighting a complex brain–body network and new directions for prevention and research.

via ScienceAlert|
#dementia#gum-disease#health
Tinnitus Demystified: Causes, Prevention, and Practical Treatments
health3 months ago

Tinnitus Demystified: Causes, Prevention, and Practical Treatments

Tinnitus is a brain-ear miscommunication often linked to hair-cell damage and age-related hearing loss. The article explains the causes, emphasizes prevention (protect ears from loud noise with proper earplugs), and describes treatments like hearing aids and Tinnitus Retraining Therapy to improve quality of life, noting there is no cure but management can help, and suggests getting a hearing test if you notice ringing.

via SciTechDaily|
#ear-health#health#hearing-loss
Revolutionary Ear Technology Paves the Way for Hearing Loss Solutions
health4 months ago

Revolutionary Ear Technology Paves the Way for Hearing Loss Solutions

Researchers at Rockefeller University have successfully kept a segment of the mammalian cochlea alive outside the body, enabling detailed study of its active sound amplification process. This breakthrough confirms that mammals rely on a universal biophysical principle involving Hopf bifurcation for amplifying faint sounds, paving the way for new treatments for sensorineural hearing loss by understanding and potentially repairing hair cell damage.

via Indian Defence Review|
#cochlea#ear-research#health
Advancements and Key Factors in Alzheimer’s and Dementia Prevention
health6 months ago

Advancements and Key Factors in Alzheimer’s and Dementia Prevention

During Alzheimer's Awareness Month, Dr. Keith Darrow and Hearing and Brain Centers of America promote proactive brain health strategies, including free assessments and resources, emphasizing the link between untreated hearing loss and increased dementia risk, and encouraging early intervention to improve quality of life and reduce future dementia cases.

via KSL.com|
#alzheimers-awareness-month#brain-health#dementia-risk-reduction