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Immune Response

All articles tagged with #immune response

GLP-1 Weight-Loss Drugs May Lower Cancer Recurrence by Boosting Immune Response, Expert Says
health14 days ago

GLP-1 Weight-Loss Drugs May Lower Cancer Recurrence by Boosting Immune Response, Expert Says

The American Association for Cancer Research's 2026 report notes that obesity is a major cancer risk factor, prompting interest in whether GLP-1 drugs like Ozempic and Mounjaro can reduce cancer incidence. While retrospective studies suggest lower cancer risk and higher survival rates for GLP-1 users, evidence remains mixed, with some studies showing increased risks for specific cancers like thyroid cancer. Dr. Sai Yendamuri of Roswell Park Comprehensive Cancer Center suggests these drugs may alter the body's immune response to fight cancer cells, potentially lowering recurrence rates in lung cancer and melanoma. However, randomized clinical trials are lacking, and it remains unclear if benefits stem from weight loss or direct immune effects. Future trials will determine if GLP-1s can serve as a preventive mechanism for cancer.

via New York Post|
#cancer-research#glp-1-drugs#health
Focused Attention Dims Inflammation in Healthy Volunteers, Bar-Ilan Study Finds
health1 month ago

Focused Attention Dims Inflammation in Healthy Volunteers, Bar-Ilan Study Finds

A Bar-Ilan University study published in Nature Human Behaviour shows that actively directing attention to an inflamed skin area reduces the inflammatory response and speeds recovery, via both sensory pathways and top-down brain mechanisms. Across three preregistered experiments with 57 healthy volunteers, about 90% showed smaller inflammation when focusing on the area, with responses roughly 1.5 times smaller and faster return to baseline. The findings suggest attention can actively shape physiological processes, though the applicability to chronic inflammation remains to be determined.

via News-Medical|
#attention#bar-ilan-university#health
Deadly fungus Candida auris hides in hair follicles as cases rise across 23 states
health2 months ago

Deadly fungus Candida auris hides in hair follicles as cases rise across 23 states

A drug‑resistant fungus Candida auris can burrow into hair follicles and alter immune signaling, creating a persistent nest on the skin. Cases have been reported in 23 states this year (Texas leads with 700+), and the fungus can linger on skin for months, making it hard to eradicate; many carriers have no symptoms, but infections can be deadly—CDC estimates up to 60% fatality among infected patients and roughly 3,000 US deaths annually. Treatment often requires multiple antifungal drugs and ongoing infection control in healthcare settings.

via New York Post|
#antifungal-resistance#candida-auris#hair-follicles
Why cyclosporiasis diarrhea can be explosive—and how your immune system decides its severity
health2 months ago

Why cyclosporiasis diarrhea can be explosive—and how your immune system decides its severity

A 2026 outbreak of cyclosporiasis in the U.S. has sickened more than 4,100 people, linked to contaminated produce from Mexico. The illness stems from Cyclospora cayetanensis infecting intestinal cells, but the severe, sometimes explosive diarrhea is largely driven by the body’s immune response—especially helper T cells and the interferon-gamma pathway. Severity and duration depend on immune strength: young children, older adults, and immunocompromised individuals are at higher risk for prolonged illness and dehydration, while repeated exposure can lessen disease severity. Diagnosis is through stool tests and treatment typically requires a 7–10 day course of antibiotics; there is no vaccine yet to prevent cyclosporiasis.

via The Conversation|
#cyclospora-cayetanensis#cyclosporiasis#diarrhea
KRAS-targeting pancreatic cancer vaccine shows early interception potential
health2 months ago

KRAS-targeting pancreatic cancer vaccine shows early interception potential

A phase 1 trial of the experimental vaccine mKRAS-VAX in 20 high-risk individuals showed robust KRAS-specific immune responses in 90% (about 18-fold on average) and no pancreatic cancer development after 16.5 months; 37.5% had shrinkage or disappearance of at-risk cysts; the vaccine appeared safe with only injection-site reactions and flu-like symptoms. The study, limited by small size and not designed to assess efficacy, suggests potential for cancer interception but requires larger trials.

via Fox News|
#health#immune-response#kras
Ink on skin, eye inflammation: tattoo-linked uveitis explained by optometrists
health6 months ago

Ink on skin, eye inflammation: tattoo-linked uveitis explained by optometrists

Tattoo-associated uveitis is a rare condition where chemicals in tattoo ink trigger an immune reaction that can breach the eye’s blood-ocular barrier and inflame the uvea, potentially causing pain, redness and light sensitivity. If left untreated, it may lead to glaucoma or cataracts and permanent vision loss. Australian studies show rising cases, with larger tattoos and black ink more often implicated, and risk factors including immune-related conditions like multiple sclerosis or certain arthritides. Treatments include steroid eye drops or injections and immunosuppressants, but outcomes vary (roughly 75% temporary vision loss and 17% permanent in some cases). If eye swelling or vision problems occur after a tattoo, consult an optometrist promptly for evaluation and possible referral to a specialist.

via The Conversation|
#eye-health#health#immune-response
Brain Parasite Toxoplasma gondii Is Stopped by Immune Cells' Self-Destruct Switch
health-and-medicine7 months ago

Brain Parasite Toxoplasma gondii Is Stopped by Immune Cells' Self-Destruct Switch

Researchers at UVA Health found that the brain parasite Toxoplasma gondii can infect CD8+ T cells, but these immune cells use the enzyme caspase-8 to trigger a self-destruct mechanism that kills the infected cell and the parasite inside. In mice lacking caspase-8 in their T cells, brain parasite levels were higher and outcomes worse, indicating caspase-8 is crucial for limiting brain infection. With about a third of people believed to carry T. gondii, most cases are asymptomatic, though toxoplasmosis remains a risk for the immunocompromised. The study, published in Science Advances, enhances understanding of how the immune system controls the parasite and why T cells’ self-destruction can prevent brain persistence.

via ScienceDaily|
#brain-infection#caspase-8#cd8-t-cells
Mindset boost linked to stronger vaccine antibodies, study finds
health8 months ago

Mindset boost linked to stronger vaccine antibodies, study finds

A study in healthy volunteers shows training people to recruit the brain's reward system through positive thinking increased their antibody response to a hepatitis B vaccine, suggesting mind–body strategies could complement vaccination. The effect was observed after four brain-training sessions and may not translate to clinical outcomes; larger trials are needed to determine practical benefits and whether other immune factors are affected.

via The Guardian|
#brain-reward-system#health#immune-response
Why a Cold Hits Some Harder: The Nasal Immune Response Holds the Key
science8 months ago

Why a Cold Hits Some Harder: The Nasal Immune Response Holds the Key

A Yale-led study using lab-grown nasal airway organoids infected with rhinovirus shows that the severity of colds depends on the early interferon response in nasal cells; robust interferon keeps infection to under 2% of cells, while blocking interferon leads to wider infection, increased inflammation and mucus, and slower cilia, explaining why symptoms vary and suggesting that boosting interferon early could help treatments.

via The Washington Post|
#common-cold#immune-response#interferon
Infections That Cause Unusual Mouth Taste
health9 months ago

Infections That Cause Unusual Mouth Taste

Unusual taste changes can be early signs of underlying health issues like infections, sinus problems, or immune responses, with recent research highlighting the role of inflammation and immune cytokines such as TNF in altering taste perception, especially bitter flavors. These symptoms often precede other symptoms and can be caused by respiratory illnesses, oral infections, medications, or neurological conditions, emphasizing the importance of investigating persistent taste disturbances.

via The Daily Galaxy|
#covid-19#health#immune-response
NIH Topical Steroid Withdrawal Study Stalls Amid Federal Disruptions
health9 months ago

NIH Topical Steroid Withdrawal Study Stalls Amid Federal Disruptions

An NIH study aimed at understanding topical steroid withdrawal (TSW), a painful skin condition, was halted due to federal budget cuts and layoffs, delaying crucial research and leaving patients without definitive answers. Despite initial promising findings suggesting microbiological differences in TSW, subsequent studies were paused, highlighting the challenges of researching contested illnesses amid bureaucratic and political upheaval.

via statnews.com|
#dermatology#health#immune-response