Tag

Ldl Cholesterol

All articles tagged with #ldl cholesterol

Cholesterol drug cuts first cardiovascular events by 31% in diabetics without artery disease
health-and-medicine11 days ago

Cholesterol drug cuts first cardiovascular events by 31% in diabetics without artery disease

A Mass General Brigham study finds the PCSK9 inhibitor evolocumab, added to standard therapy, reduces the risk of a first major cardiovascular event by 31% over ~5 years in high‑risk diabetics without diagnosed atherosclerosis, with about a 51% drop in LDL‑C. Safety was similar to placebo, suggesting earlier intensive cholesterol lowering may prevent heart attacks and strokes in patients without established artery disease; results were presented at the ACC and published in JAMA.

2026 Lipid Guidelines Use PREVENT Scores to Tailor Therapy
health27 days ago

2026 Lipid Guidelines Use PREVENT Scores to Tailor Therapy

The 2026 American dyslipidemia guideline endorses PREVENT-ASCVD risk equations to guide primary prevention therapy and suggests considering lipid-lowering treatment for adults at intermediate risk based on a 10-year PREVENT-ASCVD risk, with additional considerations for borderline risk and for patients with moderate subclinical atherosclerosis, aiming to lower LDL cholesterol.

2026 ACC/AHA Dyslipidemia Guideline Emphasizes Early Intervention and PREVENT-ASCVD
health28 days ago

2026 ACC/AHA Dyslipidemia Guideline Emphasizes Early Intervention and PREVENT-ASCVD

The 2026 ACC/AHA Guideline on Dyslipidemia consolidates evidence-based recommendations, retires the 2018 cholesterol guideline, and stresses earlier lifestyle measures from childhood along with earlier pharmacotherapy for familial hypercholesterolemia and high LDL-C. It also adopts the PREVENT-ASCVD risk equations to guide lipid-lowering therapy in adults aged 30–79, aiming to improve ASCVD prevention.

New ACC/AHA Dyslipidemia Guideline Promotes Early Lifestyle Action and Risk-Tailored Therapy
heart-news28 days ago

New ACC/AHA Dyslipidemia Guideline Promotes Early Lifestyle Action and Risk-Tailored Therapy

The ACC, AHA and partners released an updated dyslipidemia guideline that emphasizes earlier lifestyle changes, lower LDL-C targets based on individual risk, and earlier use of lipid-lowering therapies; it introduces the PREVENT-ASCVD risk calculator for primary prevention, expands testing for lipids including lipoprotein(a) and apolipoprotein B, and recommends selective use of coronary calcium scoring to guide treatment decisions, with guidance extending to pediatric screening and different populations to reduce lifetime ASCVD risk.

Two Days of Oats Trim LDL Cholesterol by 10% and Rewire Gut Bacteria
health-and-medicine1 month ago

Two Days of Oats Trim LDL Cholesterol by 10% and Rewire Gut Bacteria

A two-day, calorie-restricted, oat-dominant diet reduced LDL cholesterol by 10% in people with metabolic syndrome, with modest weight loss and lower blood pressure, and benefits persisted six weeks. The effect appears linked to changes in gut bacteria and their metabolites; a longer, less intensive oat plan yielded smaller gains.

Two-Day Oatmeal Diet Cuts LDL by 10%, Study Finds
health1 month ago

Two-Day Oatmeal Diet Cuts LDL by 10%, Study Finds

A German study from the University of Bonn found that consuming 300 grams of oats per day on a calorie‑restricted diet for two days lowered “bad” LDL cholesterol by about 10%, with slight weight loss and blood pressure reductions among adults with metabolic syndrome; the effect may stem from gut microbiome changes. While oats aren’t a replacement for medication, short, regular oat-based diets could help keep cholesterol in the normal range and may reduce diabetes risk, though diabetics should monitor carbs and ensure gluten-free oats if needed.

Partial adherence to the Portfolio Diet lowers LDL cholesterol, new evidence shows
health2 months ago

Partial adherence to the Portfolio Diet lowers LDL cholesterol, new evidence shows

The Portfolio Diet—built around plant protein, nuts and seeds, viscous fiber, plant sterols and monounsaturated fat—significantly lowers LDL cholesterol, with about a 28% reduction when fully followed and a meaningful 14% drop with partial adherence; endorsed by major health organizations, it’s practical to start with small changes (e.g., plant-based proteins, oats, nuts, olive oil) for cardiovascular benefits.

Understanding LDL Cholesterol and Ways to Reduce It
health3 months ago

Understanding LDL Cholesterol and Ways to Reduce It

LDL cholesterol, often called 'bad' cholesterol, can build up silently in arteries, increasing the risk of heart disease and stroke. It is essential to have regular blood tests to monitor levels, ideally keeping LDL below 100 mg/dL, and to understand that genetics and aging also influence cholesterol levels. Managing diet, lifestyle, and regular check-ups are key to controlling LDL cholesterol and maintaining heart health.

Cholesterol Changes Linked to Dementia Risk in Older Adults
health1 year ago

Cholesterol Changes Linked to Dementia Risk in Older Adults

A new study suggests that fluctuating cholesterol levels in older adults may increase the risk of dementia and cognitive decline. The research, presented at the American Heart Association’s Scientific Sessions 2024, found that those with the highest fluctuations in total cholesterol and LDL-C had a significantly higher likelihood of developing dementia. The study highlights the potential of using annual cholesterol tracking as a biomarker for dementia risk, though further research is needed to understand the relationship between cholesterol variability and cognitive health.

Variable Cholesterol Levels May Increase Dementia Risk
health1 year ago

Variable Cholesterol Levels May Increase Dementia Risk

A study involving nearly 10,000 older adults found that significant fluctuations in cholesterol levels, particularly LDL cholesterol, are linked to a higher risk of dementia and cognitive decline, independent of medication changes. The research suggests cholesterol variability could serve as a biomarker for cognitive health, potentially guiding future therapies aimed at stabilizing cholesterol levels to support brain health. The study highlights the need for further research to understand the role of cholesterol in dementia.

Breakthrough Vaccine Lowers Cholesterol, Revolutionizing Heart Health
health2 years ago

Breakthrough Vaccine Lowers Cholesterol, Revolutionizing Heart Health

Researchers at The University of New Mexico School of Medicine have developed a vaccine that could lower "bad" LDL cholesterol, which can lead to heart disease and stroke. The vaccine, which targets the PCSK9 protein, has been shown to reduce cholesterol levels by up to 30% in animal studies. The researchers hope to move into vaccine manufacturing and clinical trials with humans in the next few years, with the goal of creating a pure, safe, and affordable vaccine that could have a global impact on heart disease.

Vegan Diet Rapidly Improves Heart Health, According to Studies
health2 years ago

Vegan Diet Rapidly Improves Heart Health, According to Studies

A study conducted by researchers from Stanford University suggests that following a vegan diet can lead to improved cardiovascular health compared to an omnivore diet. The study, which involved pairs of identical twins, found that participants following a vegan diet experienced lower levels of LDL cholesterol and fasting insulin, as well as greater weight loss. While not everyone may want to adopt a vegan diet, even small changes towards a more plant-based diet can have positive effects on cardiovascular health. Medical experts recommend increasing the intake of heart-healthy foods such as fruits, vegetables, nuts, legumes, and whole grains.