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Liver Cancer

All articles tagged with #liver cancer

AI-Driven Blood Test Detects Liver Cancer Across Diverse Populations
health27 days ago

AI-Driven Blood Test Detects Liver Cancer Across Diverse Populations

Johns Hopkins researchers validated an AI-powered DELFI liquid biopsy that detects liver cancer across two geographically and biologically distinct populations (Guatemala and Romania). When combined with AFP and basic risk factors, the test identified both early- and late-stage cancers with greater sensitivity than current blood tests, by analyzing genome-wide DNA fragment patterns that reflect signals from tumor, liver cells, blood vessels, and immune responses. The study also noted region-specific molecular signatures (e.g., aflatoxin-associated patterns in Guatemala) while the overall classifier remained effective across cancer causes. Future work will include prospective validation and integrating fragmentome analysis with other biomarkers for even earlier detection.

via News-Medical|
#artificial-intelligence#cell-free-dna#fragmentome
Coffee Linked to Lower Liver Disease Risk in a Massive UK Biobank Study
health1 month ago

Coffee Linked to Lower Liver Disease Risk in a Massive UK Biobank Study

A UK Biobank analysis of nearly 355,000 adults over about 13 years found that drinking five or more cups of coffee daily is linked to a lower risk of liver cirrhosis (32%), liver cancer (47%), and death from liver-related causes (42%), with benefits seen for both regular and decaf coffee. The protective effects are likely due to coffee's bioactive compounds beyond caffeine, such as polyphenols and antioxidants, which may reduce inflammation and fibrosis. While decaf also appears beneficial, more research is needed and the findings are not a directive to drink large amounts—moderation can be part of liver health strategies.

via Women's Health|
#cirrhosis#coffee#decaf-coffee
Daily Coffee Linked to Major Drop in Liver Cancer Risk, UK Study Says
health1 month ago

Daily Coffee Linked to Major Drop in Liver Cancer Risk, UK Study Says

A UK Biobank analysis of about 355,000 adults followed for ~13 years found that five or more daily cups of coffee were linked to a 32% lower risk of cirrhosis, a 47% lower risk of liver cancer, and a 42% lower risk of death from liver-related causes versus non-coffee drinkers; benefits were seen with regular and decaf coffee, suggesting non-caffeine compounds like polyphenols may drive the liver protection. While observational, the results support moderate unsweetened coffee as a potential liver-disease prevention strategy, though causality isn’t proven and more research is needed.

via AOL.com|
#coffee#decaf-coffee#health
Coffee Tied to Lower Liver Disease Risk in Large UK Biobank Study
health1 month ago

Coffee Tied to Lower Liver Disease Risk in Large UK Biobank Study

Analyzing UK Biobank data over a median of 13 years in 354,957 adults, researchers found that higher coffee intake is linked to lower risks of cirrhosis, liver cancer, and liver-related death; MRI and proteomic data showed healthier liver tissue and metabolism in coffee drinkers, with benefits beginning at 1–2 cups daily and seen for both caffeinated and decaf coffee. The study is observational and cannot prove causation, so moderation is advised and coffee should not replace other liver-protective habits. Future work aims to identify the specific coffee compounds involved.

via SciTechDaily|
#cirrhosis#coffee#health
Big Coffee Study Finds Daily Cups May Lower Liver Disease and Liver Cancer Risk
health1 month ago

Big Coffee Study Finds Daily Cups May Lower Liver Disease and Liver Cancer Risk

A UK Biobank analysis of about 355,000 adults over roughly 13 years links coffee intake to substantially lower risks of cirrhosis, liver-related death, and hepatocellular carcinoma, with stronger protection at higher consumption (one to two cups daily reduces cirrhosis by ~20% and liver mortality by ~31%; five or more cups reduces cirrhosis by ~32%, liver death by ~42%, and liver cancer by ~47%). Benefits were similar for caffeinated and decaf coffee and persisted with or without sugar, though added sugars may blunt some effects. Being observational and based on self-reported data, the study shows correlation rather than causation and coffee should complement—not replace—standard preventive health practices.

via Fox News|
#coffee#health#liver-cancer
Silent signals: catching liver cancer before it whispers
health1 month ago

Silent signals: catching liver cancer before it whispers

Liver cancer often grows quietly due to the liver’s large reserve capacity, so early signs are vague and easily mistaken for other issues. Key warning signs include unexplained weight loss, persistent fatigue, reduced appetite, and right‑sided abdominal pain; as it progresses, ascites and jaundice may appear. Those with hepatitis B or C, cirrhosis, MAFLD, or a family history are at higher risk. Early detection via blood tests (including liver function and AFP), ultrasound, CT or MRI improves treatment outcomes, with regular surveillance recommended for high‑risk groups. Preventive steps include hepatitis vaccination, limiting alcohol, maintaining a healthy weight, managing diabetes and fatty liver disease, and routine health screenings.

via The Times of India|
#early-symptoms#health#hepatitis-b
Coffee May Shield Liver From Disease and Cancer, Large Study Finds
health1 month ago

Coffee May Shield Liver From Disease and Cancer, Large Study Finds

A large, long-term study of more than 354,000 participants found that regular coffee consumption is associated with lower risks of cirrhosis, liver cancer, and liver-related death, with bigger risk reductions at higher intake (even five cups or more). The study suggests the benefit may stem from coffee's antioxidants rather than caffeine, since decaffeinated coffee showed similar effects. Additives like sugar slightly dampen the benefit. The authors caution that these are associations, not proof of causation, and limitations include baseline-only coffee intake data and a predominantly European, health-conscious cohort. Coffee may have other health benefits as well, but moderation of sugar and caffeine is advised per guidelines.

via CNN|
#coffee#health#liver-cancer
Preventable liver disease propels rise in liver cancer deaths worldwide
health2 months ago

Preventable liver disease propels rise in liver cancer deaths worldwide

Liver cancer deaths are rising globally, including in the UK, with most cases linked to preventable liver disease caused by obesity, type 2 diabetes, excess alcohol, and viral hepatitis. At least 60% of primary liver cancers may be preventable by addressing these risk factors. Early detection and lifestyle changes can reduce risk and improve survival, but without urgent government action—such as restricting alcohol and ultra-processed foods, expanding addiction services and hepatitis testing, and implementing policy reforms—the trend is unlikely to reverse.

via ScienceAlert|
#cancer-prevention#health#liver-cancer
Adulthood weight gain tied to higher cancer risk across multiple cancers, study shows
health3 months ago

Adulthood weight gain tied to higher cancer risk across multiple cancers, study shows

A Swedish study of more than 600,000 people found that gaining weight in adulthood and starting adulthood with a higher weight increases overall cancer risk, with no safe age to gain weight. Early obesity (before 30) dramatically raises risks: men see a fivefold rise in liver cancer and doubles in pancreatic and kidney cancers, while women see about 4.5× higher endometrial cancer risk. Weight gain later in life also raises risk, with women showing strong links to endometrial, postmenopausal breast, and meningioma, and men to esophageal and liver cancers. Those who gained the most weight (~32 kg) faced about 7% higher cancer risk than those who gained little (~8 kg). Even modest weight gain elevates risk, underscoring the importance of maintaining a stable, healthy weight throughout adulthood, the authors say.

via The Guardian|
#adult-weight-gain#cancer#health
Protein-lean diet slows liver cancer in diseased livers, mouse study suggests
science6 months ago

Protein-lean diet slows liver cancer in diseased livers, mouse study suggests

Rutgers-led scientists in Science Advances show that in mice with liver impairment, reducing dietary protein slowed liver tumor growth and extended survival. By impairing ammonia disposal, ammonia increased and was redirected into amino acids and nucleotides that tumors use for growth, suggesting ammonia metabolism fuels cancer in diseased livers. The findings imply that a low-protein diet could lower liver cancer risk or progression for people with liver disease—but doctors caution against self-prescribing such diets, since protein also supports strength during treatment and liver function varies. More research is needed to translate to humans.

via SciTechDaily|
#ammonia#diet#liver-cancer