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Long Term Use

All articles tagged with #long term use

Long-Term Melatonin Use Linked to Higher Heart Failure Risk, Preliminary Findings
science19 days ago

Long-Term Melatonin Use Linked to Higher Heart Failure Risk, Preliminary Findings

A large, multi-country analysis of about 130,000 adults found that long-term melatonin prescriptions (>1 year) were associated with an 89% higher risk of heart failure and roughly double the odds of death over five years versus those not prescribed melatonin. The study is preliminary, not peer‑reviewed, and relies on prescription records to infer melatonin use—OTC use in the control group could bias results. While melatonin is commonly used and generally safe short‑term, these findings underscore the need for prospective trials to clarify safety and guidance for long-term use.

via ScienceAlert|
#heart-failure#long-term-use#melatonin
Nordic Study Finds No Link Between Long-Term Heartburn Meds and Stomach Cancer
health5 months ago

Nordic Study Finds No Link Between Long-Term Heartburn Meds and Stomach Cancer

A 26-year Nordic registry-based study across Denmark, Finland, Iceland, Norway, and Sweden found no increased stomach cancer risk with long-term (over one year) use of proton pump inhibitors or H2 receptor antagonists after adjusting for age, sex, Helicobacter pylori infection treatment, ulcer history, smoking, alcohol-related diseases, obesity or diabetes, and other factors. While observational and unable to prove causation, the study mitigates biases of earlier research and suggests safety for patients reliant on these medications.

via SciTechDaily|
#gastric-cancer#health#long-term-use
Potential Heart Risks Linked to Long-Term Melatonin Use
health8 months ago

Potential Heart Risks Linked to Long-Term Melatonin Use

New preliminary research suggests that long-term use of melatonin supplements may be associated with an increased risk of heart failure and higher mortality, raising concerns about its safety beyond short-term use. The study analyzed health records from over 130,000 adults and found significant associations, though limitations in methodology mean further research is needed. Despite its popularity and general safety for short-term use, these findings highlight the importance of cautious long-term consumption and further investigation into melatonin's effects.

via ScienceAlert|
#health#heart-failure#long-term-use
health9 months ago

NHS Warns of Serious Side Effects from Widely Used Omeprazole

The NHS has issued a warning about the long-term use of omeprazole, a common medication for heartburn and acid reflux, highlighting serious potential side effects such as vitamin B12 deficiency, weakened bones, allergic reactions, and lupus, especially with prolonged use over a year. Users are advised not to take it without a prescription for more than two weeks and to consult a doctor if symptoms persist or worsen.

via LADbible|
#health#long-term-use#nhs-warning
Neurologist warns common drug may raise dementia risk by 33%
health10 months ago

Neurologist warns common drug may raise dementia risk by 33%

A study suggests that long-term use (over 4.5 years) of proton pump inhibitors (PPIs), common medications for acid reflux, may be associated with a 33% increased risk of developing dementia, though it does not establish causation. The research analyzed data from over 5,700 participants and highlights the need for further investigation and consultation with healthcare providers before making changes to medication routines.

via The Mirror|
#acid-reflux#dementia#health
Gabapentin Use May Significantly Increase Dementia and Cognitive Risks
health11 months ago

Gabapentin Use May Significantly Increase Dementia and Cognitive Risks

Recent studies suggest that long-term or frequent use of gabapentin may be associated with an increased risk of dementia and mild cognitive impairment, especially in users aged 35-64. While not proving causation, these findings prompt a reevaluation of its long-term use, emphasizing the importance of consulting healthcare providers, exploring alternatives, and adopting lifestyle measures to protect brain health.

via Times of India|
#cognitive-impairment#dementia-risk#gabapentin
Experts Warn of Hidden Dangers and Long-Term Risks of Antidepressant Withdrawal
health1 year ago

Experts Warn of Hidden Dangers and Long-Term Risks of Antidepressant Withdrawal

Experts warn that antidepressant withdrawal is a significant public health issue, especially for long-term users, with recent research indicating severe and lasting withdrawal symptoms that are often underestimated due to reliance on short-term, industry-funded studies. The UK government now recognizes this problem, which has been historically overlooked due to outdated guidelines and limited long-term data. A new review suggests current studies may underestimate withdrawal risks, emphasizing the need for better understanding and management of antidepressant discontinuation.

via ScienceAlert|
#antidepressant-withdrawal#health#long-term-use
Reevaluating Antidepressant Withdrawal Risks and Long-Term Effects
health1 year ago

Reevaluating Antidepressant Withdrawal Risks and Long-Term Effects

A new review downplays the severity of antidepressant withdrawal effects, relying on short-term, industry-funded studies, despite evidence showing long-term users face significant, often severe, withdrawal symptoms that can last for months, highlighting a potential underestimation of the risks associated with long-term antidepressant use.

via The Conversation|
#antidepressant-withdrawal#drug-industry-influence#health