
One Psilocybin Dose May Rewire the Brain for Weeks
A UCSF and Imperial College London study found that a single 25 mg dose of psilocybin increases brain entropy during the experience and is followed by lasting changes in brain connectivity for about a month, alongside reported boosts in psychological insight and well-being. The results suggest the psychedelic experience itself may drive durable mental health benefits and could inform optimized psilocybin-based therapies.






