
Taste Buds Reveal Why Some Post-COVID Flavors Stay Gone
A study in Chemical Senses followed 28 adults with lasting post-COVID taste changes, finding both weakened molecular signaling in taste cells and structural anomalies in taste buds; eight participants had clearly abnormal taste scores, with sweet, bitter, and umami most affected while salty and sour were largely preserved. Biopsies showed disorganized taste buds and atypical taste cells, though no SARS-CoV-2 genetic material was detected in the tissue, suggesting the virus doesn't linger there. The researchers propose that initial infection-triggered inflammation or nerve signaling disruption may underlie persistent taste loss, which can persist even as taste buds regenerate, highlighting cellular targets for future treatments.






