Yale Study Identifies Metformin and Semaglutide as Top Anti-Aging Interventions
A Yale University study published in Nature Medicine analyzes 51 human trials to determine which interventions actually lower biological age. The research confirms that lifestyle changes and specific prescription drugs, notably metformin and semaglutide, significantly reduce epigenetic age markers. In contrast, over-the-counter supplements and certain medical procedures showed minimal impact. While these biomarker shifts suggest a slowing of biological aging, researchers caution that a younger clock reading does not yet guarantee longer life or reduced disease risk.













