Tag

Arginine

All articles tagged with #arginine

science22 days ago•4 min saved

Arginine Could Reinforce Immune Alarm Signals in Cancer and Viral Infections

Arginine deficiency weakens immune surveillance by lowering MHC-1 production, and a modest dietary boost could restore this immune signal. In cell culture and mouse studies of colon cancer and viral infections (influenza and SARS-CoV-2), higher arginine reduced tumors and improved outcomes, hinting that arginine supplementation might complement immunotherapies or help at-risk groups. Since arginine levels decline with age and poor nutrition, this could partly explain increased cancer and infection vulnerability.

via ScienceDaily|

#arginine #cancer #immune-system

science3 months ago•10 min saved

Common amino acid arginine slows Alzheimer’s pathology in animals

Japanese researchers found that arginine, a safe and inexpensive amino acid, reduced amyloid-β aggregation, decreased brain inflammation, and improved behavior in fruit flies and mice models of Alzheimer’s disease. The effects appear to come from interfering with protein misfolding rather than lowering production. While promising and eligible for repurposing, the work is preclinical and dosing differs from dietary supplements, so larger preclinical and human studies are needed before clinical use.

via SciTechDaily|

#alzheimers-disease #amyloid-beta #arginine

health-and-medicine3 months ago•6 min saved

Affordable Arg: Arginine Slows Alzheimer’s Damage in Animal Models

A Kindai University study shows that the inexpensive amino acid arginine can reduce amyloid-β buildup and brain inflammation in Alzheimer’s models (flies and mice), improving behavior; given its safety and low cost, arginine could be a rapid candidate for repurposing, but human trials and optimal dosing are still needed.

via ScienceDaily|

#alzheimers-disease #amyloid-beta #arginine

science7 months ago•4 min saved

Arginine in Saliva May Turn Mouth Biofilms from Detrimental to Protective

A Danish study from Aarhus University suggests that increasing arginine levels in saliva can shift mouth biofilms from acid-producing to protective, reducing tooth decay risk. In a real-world denture-biofilm setup, arginine treatment raised pH after sugar exposure, altered the bacterial and sugar composition, and reduced acid-producing Streptococcus populations, though responses varied among individuals. Arginine appears safe and could be explored as an additive in toothpaste or mouthwash, warranting further clinical research.

via ScienceAlert|

#arginine #biofilms #dental-health

health8 months ago•2 min saved

Simple Amino Acid Supplement Shows Promise in Reversing Alzheimer’s Signs in Mice

Scientists in Japan found that the existing drug arginine, used for high blood pressure, can reduce amyloid-beta plaques and improve cognitive function in mice with Alzheimer's-like symptoms, suggesting potential for repurposing as a treatment, though human trials are needed.

via Futurism|

#alzheimers #arginine #brain-plaques

health9 months ago•5 min saved

Potential Drug Reverses Genetic Hearing Loss, Scientists Find

Scientists discovered that mutations in the CPD gene cause a rare inherited form of hearing loss by disrupting arginine and nitric oxide signaling in inner ear cells. They found that existing drugs like Viagra and arginine supplements could potentially reverse this damage, offering a promising treatment avenue for this genetic condition.

via SciTechDaily|

#arginine #cpd-gene #genetic-mutation

health11 months ago•4 min saved

Salmonella and Yeast: A Harmful Gut Partnership

Research shows that the gut yeast Candida albicans can enhance Salmonella Typhimurium infection by promoting its invasion through arginine production, which suppresses inflammation and facilitates bacterial spread, highlighting a harmful cross-kingdom interaction in the gut.

via Medical Xpress|

#arginine #candida-albicans #gut-microbiome

health11 months ago•3 min saved

Sucralose May Undermine Cancer Treatments, New Research Finds

Research indicates that sucralose may impair cancer immunotherapy effectiveness by disrupting gut bacteria and reducing arginine levels, but supplementing with arginine or citrulline could counteract these effects, offering a potential simple intervention for patients consuming artificial sweeteners during treatment.

via ScienceDaily|

#arginine #cancer #health

biology11 months ago•82 min saved

Yeast Boosts Salmonella Virulence

Commensal yeast C. albicans enhances Salmonella Typhimurium virulence by producing arginine, which increases bacterial invasion and dampens host immune response, thereby promoting infection severity.

via Nature|

#arginine #biology #c-albicans