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Genome-wide study links anxiety severity to gut-brain axis and shared genetics with heart disease
science1 month ago

Genome-wide study links anxiety severity to gut-brain axis and shared genetics with heart disease

A large, continuous-spectrum GWAS of anxiety symptoms (693,869 European-ancestry participants) identified 74 genetic loci (39 new) and revealed notable genetic overlap with irritable bowel syndrome (r≈0.57) and modest overlaps with coronary artery disease and migraine. The study estimates about 6% of anxiety symptom variation is explained by common variants, with the rest shaped by environment and gene–environment interactions; researchers caution that correlations do not imply causation and emphasize methodological advances (dimensional analysis) and the need for more diverse datasets. It complements clinically diagnosed anxiety genetics work and highlights gut–brain axis as a key area for future research.

via Space Daily|
#anxiety#genetics#gut-brain-axis
Clinicians Embrace Bowel Hygiene to Boost Gut Health
health1 month ago

Clinicians Embrace Bowel Hygiene to Boost Gut Health

Clinicians are increasingly embracing a concept called bowel hygiene, emphasizing fiber- and hydration-rich diets, regular physical activity, healthy toileting habits, mind-body practices, and consistent daily routines to improve gut motility, microbial diversity, and stress resilience—an approach that could enhance patient counseling and public health education even as formal validation continues.

via Medscape|
#bowel-hygiene#constipation#gut-brain-axis
Your Colon Has Its Own Clock, Explaining Morning Urges
health1 month ago

Your Colon Has Its Own Clock, Explaining Morning Urges

Scientists found clock genes in the colon’s nerve tissue that regulate bowel movements on a daily rhythm, with nitric oxide acting as a braking signal that loosens as wake time approaches. The resulting surge in colonic activity occurs after waking and after meals due to the gastrocolic reflex, cortisol, and meal-triggered signals. Disrupting this rhythm with shift work or travel is linked to IBS-like symptoms, while practical guidance—consistent wake time, morning light, a short post-breakfast toilet routine, fiber, water, and light activity—helps the colon finish the job.

via Indian Defence Review|
#circadian-rhythm#gastrocolic-reflex#gastroenterology
Five subtle signs of bowel cancer you should not ignore
life-style2 months ago

Five subtle signs of bowel cancer you should not ignore

A health feature outlines five early warning signs of bowel cancer—blood in the stool, persistent changes in bowel habits, abdominal pain, bloating, and unexplained weight loss—and urges anyone experiencing these symptoms to see a GP promptly. The piece highlights the value of early reporting for better outcomes and explains NHS screening options, including at-home FIT tests and follow-up tests like colonoscopy or CT scans if results are positive.

via The Independent|
#blood#bowel-cancer#cancer
When Breakfast Becomes a Trigger: Inulin’s Role in IBS Symptoms
health2 months ago

When Breakfast Becomes a Trigger: Inulin’s Role in IBS Symptoms

A gastroenterologist links persistent IBS-like symptoms to a specific breakfast ingredient: added inulin (chicory root fiber) found in fortified cereals and yogurts. In sensitive guts, such fermentable fibers can cause gas, pain, and urgency. By removing inulin-filled breakfasts for two weeks and re‑challenging, patients often identify a clear trigger, leading to personalized, timed fiber strategies rather than demonizing fiber entirely. About two‑thirds of IBS-D patients improved after breakfast simplification, underscoring the need to tailor dietary changes to the individual.

via Iowa Park Leader|
#fiber#gut-health#health
Experts Reveal 25 Quick Tricks to Ditch Bloat Fast
health3 months ago

Experts Reveal 25 Quick Tricks to Ditch Bloat Fast

Experts explain bloating is common and can stem from gas, constipation, diet, or IBS, and outline 25 practical fixes—from staying hydrated and monitoring salt to probiotics, gentle exercise after meals, and mindful eating—that help reduce bloating quickly and safely. They also discuss when to use OTC aids like simethicone, the potential benefits of ginger, prebiotics, and digestive enzymes, and note that a low-FODMAP plan should be done with a registered dietitian; seek medical advice for sudden, persistent, or alarming symptoms.

via AOL.com|
#bloating#digestion#gut-health
Gravity on the gut: a new theory linking IBS to gravity tolerance
science4 months ago

Gravity on the gut: a new theory linking IBS to gravity tolerance

A Cedars-Sinai doctor advances a novel “gravity intolerance” theory suggesting IBS risk may hinge on how the body tolerates gravity. Using a framework called the G-force cube (resistance, detection, vigilance), he argues gravity-related factors could unify IBS with related conditions like anxiety, pain sensitivity (fibromyalgia), and POTS. The idea is preliminary and not a replacement for established IBS factors (bacteria, inflammation, diet, genetics); more research is needed, but gravity may help organize known risk factors and guide future study.

via Space|
#gastroenterology#gravity#gut-brain-axis
When IBS masked cancer: a 37-year-old's stage-3 colon cancer diagnosis
health5 months ago

When IBS masked cancer: a 37-year-old's stage-3 colon cancer diagnosis

Healthy 37-year-old Mohammad Samad experienced abdominal pain, bloating, and constipation that were misattributed to stress, IBS, and Crohn’s disease, delaying a diagnosis of stage-3 colon cancer. After a colonoscopy confirmed the tumor, he underwent chemotherapy and emergency surgery when infections prevented further treatment, the tumor grew to the size of a watermelon, and he required a stoma and nerve damage. He is now cancer-free for two years, with his tumor testing positive for Lynch syndrome, and he has launched a blog to raise awareness about rising cancer rates among young people and the need for earlier screening and awareness.

via Business Insider|
#colon-cancer#early-onset-cancer#health
Estrogen may amplify gut pain, offering clues to IBS gender gap
health5 months ago

Estrogen may amplify gut pain, offering clues to IBS gender gap

A new preclinical mouse study suggests estrogen heightens gut-pain sensitivity by acting on rare gut-lining L-cells, which increases OLFR78 receptor activity and boosts serotonin release via the PYY pathway, altering nerve signaling to the brain. Removing ovaries lowers estrogen and reduces pain sensitivity, while restoring estrogen brings it back, potentially explaining why IBS is more common and severe in women. The findings hint at potential targets (PYY/OLFR78) for IBS therapies, though translating mouse results to humans requires caution.

via Live Science|
#estrogen#gut-pain#health
Top Low-FODMAP Foods for Reduced Bloating and Improved Digestion
health-and-wellness8 months ago

Top Low-FODMAP Foods for Reduced Bloating and Improved Digestion

The article explains the low-FODMAP diet, which involves avoiding certain fermentable carbohydrates that can cause bloating, gas, and other digestive issues, especially for those with IBS. It highlights which foods are low in FODMAPs, such as certain vegetables, fruits, meats, nuts, and seeds, and discusses the importance of working with a healthcare professional to avoid nutritional deficiencies while managing symptoms.

via Vogue|
#digestive-health#fodmap#gut-health