All articles tagged with #neurodegenerative
Neurologists warn that GLP-1 receptor agonists used for obesity and diabetes, including Ozempic and Wegovy, might hasten decline in neurodegenerative diseases like ALS due to rapid weight loss; a 2025 ALS case report and retrospective data prompt caution, while experts stress weight maintenance is crucial and Novo Nordisk notes ALS is not listed as a drug warning.
A Nature Medicine study of 52 donated brains found higher microplastic levels in brains from people with dementia than in those without; 2024 samples contained more microplastics than 2016, suggesting an association (not causation) between microplastics and neurodegenerative conditions and underscoring the need for further research and stronger plastic-reduction efforts.
South Korean research shows that patients with restless legs syndrome (RLS) have a higher risk of developing Parkinson's disease, but treatment with dopamine agonists appears to offer a protective effect, delaying or reducing the incidence of Parkinson's. The study suggests early management of RLS could be crucial for long-term neurological health.
A small, early study suggests that the gene therapy AMT-130 may slow Huntington's disease progression, but results are preliminary, unreviewed, and require further research to confirm efficacy and safety.
A new gene therapy for Huntington's disease has shown to slow disease progression by 75%, offering hope for treatment and potentially transforming patient outcomes, though regulatory and cost hurdles remain before it can be widely available on the NHS.
Preliminary results from a small clinical trial show that a gene therapy injected into the brain can slow the progression of Huntington’s disease by 75%, marking a significant breakthrough in treatment for this neurodegenerative condition.
An experimental gene therapy called AMT-130 from Uniqure significantly slowed Huntington's disease progression by 75% over three years, potentially paving the way for the first genetic treatment approval for this neurodegenerative disorder.
Bruce Willis has moved into a nearby 'second home' to receive 24-hour care due to his frontotemporal dementia, allowing his family to better support his needs and maintain daily contact, while he remains physically healthy but experiences language decline.
Scientists have developed a novel technique called 'nano-pulling' using magnetic nanoparticles to guide and promote the growth of nerve fibers in lab-grown mini-brains, showing promise for repairing brain connections damaged in Parkinson's disease, potentially aiding future treatments.
A study suggests that Human Pegivirus (HPgV), previously considered harmless, may be linked to Parkinson's disease as it was found in the brains of patients with the disorder but not in healthy individuals, indicating a potential environmental factor influencing disease development.
A study suggests that the Human Pegivirus (HPgV), previously considered harmless, may be linked to Parkinson's disease, as it was found in the brains of patients but not in healthy individuals, indicating a potential environmental factor influencing the disease's development.
A study of nearly 93,000 Americans found that following the MIND diet, which emphasizes plant-based foods, berries, green leafy vegetables, and fish while limiting red meat and processed foods, is associated with a 9% lower risk of developing dementia, with even greater benefits over time. Experts suggest that such a balanced diet may improve cardiovascular health and blood flow to the brain, potentially reducing dementia risk, though causality has not been established.
A study involving over 22,000 people with multiple sclerosis (MS) has identified a genetic variant associated with faster disease progression. The variant, located between two genes involved in repairing damaged cells and controlling viral infection, was found to accelerate the need for walking aids by almost four years when inherited from both parents. The findings suggest that resilience and repair in the nervous system play a crucial role in determining the course of MS progression, providing new opportunities for developing therapies to preserve the health of MS patients.
Actor Michael J. Fox, who was diagnosed with Parkinson's disease at 29, says living with the condition is getting harder. A new documentary called "Still: A Michael J. Fox Movie" is coming out on Apple TV+ next month detailing his struggles and triumphs over the past decades. Parkinson's is the second-most common neurodegenerative disease in the U.S. after Alzheimer's. Fox created The Michael J. Fox Foundation for Parkinson's Research in 2000, which has raised $1.75 billion to date.