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Superagers

All articles tagged with #superagers

Why some octogenarians stay sharp: brain biology and social life unlock memory resilience
health-and-medicine1 month ago

Why some octogenarians stay sharp: brain biology and social life unlock memory resilience

Northwestern researchers highlight 'SuperAgers'—people over 80 who score memory tests like those decades younger—whose brains either resist Alzheimer’s pathology (plaques/t tangles) or tolerate it without cognitive decline. Key traits include high social engagement, preserved cortical thickness (even thicker anterior cingulate in some), and distinctive cells like von Economo neurons and larger entorhinal neurons. Brain donations enable long-term study, and findings could guide new strategies to delay or prevent dementia.

via Science Daily|
#aging#alzheimers-disease#brain-biology
Five Habits That May Boost Your Lifespan, According to SuperAgers
wellness2 months ago

Five Habits That May Boost Your Lifespan, According to SuperAgers

Researchers studying SuperAgers identify five habits linked to longer life and better brain health: move your body regularly (even walking), stay socially engaged, reduce controllable stress, challenge your brain, and make time for activities you enjoy; while there’s no guaranteed roadmap to becoming a SuperAger, these practices align with evidence on healthy aging.

via HuffPost|
#aging#brain-health#longevity
SuperAgers’ brains stay sharp through extra neuron growth
health2 months ago

SuperAgers’ brains stay sharp through extra neuron growth

A Nature study finds SuperAgers (people 80 and older with unusually preserved cognition) generate more new neurons in the hippocampus than other older adults, suggesting that increased neurogenesis may help maintain brain health. The findings point to a unique resilience signature in SuperAgers but are based on post‑mortem, cross‑sectional data, so they show associations rather than proving that boosting neurogenesis prevents dementia. The researchers and clinicians emphasize that lifestyle factors—regular aerobic exercise, a Mediterranean-style diet, lifelong learning, social engagement, and adequate sleep—may support brain renewal and cognitive health.

via Medical News Today|
#aging#cognition#health
Secret Brain-Cell Growth May Drive Superagers' Sharp Memories
science2 months ago

Secret Brain-Cell Growth May Drive Superagers' Sharp Memories

A study of 38 postmortem brains links exceptional memory in superagers to higher hippocampal neurogenesis, finding roughly twice as many immature neurons as in typical older adults; Alzheimer's groups show reduced immature neurons, while genetic data point to stronger synaptic plasticity and BDNF activity in superagers, suggesting neurogenesis as a driver of cognitive resilience and a potential therapeutic target.

via ScienceAlert|
#aging#alzheimers-disease#hippocampus
Cellular clues explain why some octogenarians stay mentally sharp
science3 months ago

Cellular clues explain why some octogenarians stay mentally sharp

A study of self-described “SuperAgers”—people over 80 with exceptional memory—shows they have more newly formed neurons and a hippocampal environment that supports neurogenesis, along with thicker attention-related brain regions and fewer tau tangles than typical aging. Using multiomic single-cell sequencing across donor brains, researchers found astrocytes and CA1 neurons drive memory retention, suggesting that a combination of genetics and brain-healthy lifestyle supports sustained cognition into advanced age.

via CNN|
#aging#hippocampus#memory
Genetic Variants Linked to Dementia Resilience in Superagers, Study Finds
science4 months ago

Genetic Variants Linked to Dementia Resilience in Superagers, Study Finds

In a study of 18,080 participants (1,623 superagers aged 80+, 8,829 with Alzheimer's, 7,628 controls), researchers found that superagers are less likely to carry the APOE-e4 Alzheimer's-risk variant and more likely to carry APOE-e2, suggesting genetics contribute to exceptional aging and reduced dementia risk. The pattern held in non-Hispanic White groups, highlighting a potential genetic basis for dementia resilience, though lifestyle and other factors remain important, and more diverse research is needed.

via ScienceAlert|
#alzheimers-disease#apoe-e2#apoe-e4
Scientists Discover Why Some 80-Year-Olds Have the Memory of 50-Year-Olds
health7 months ago

Scientists Discover Why Some 80-Year-Olds Have the Memory of 50-Year-Olds

Research from Northwestern University identifies traits and brain features of 'SuperAgers'—80-year-olds with memory skills comparable to much younger individuals—highlighting factors like brain structure, social engagement, and resistance or resilience to Alzheimer's-related proteins, which could inform future interventions to preserve cognitive health in aging.

via Yahoo|
#alzheimers#brain-health#cognitive-decline
Scientists Uncover Why 'SuperAgers' Maintain Youthful Brains
health7 months ago

Scientists Uncover Why 'SuperAgers' Maintain Youthful Brains

A 25-year study reveals that superagers, individuals over 80 with memory skills of much younger people, have unique brain features such as resistance to Alzheimer's-related proteins, higher neuron concentrations, and less inflammation, which may explain their preserved cognitive abilities and could lead to new brain health interventions.

via ScienceAlert|
#alzheimers-resistance#brain-health#cognitive-decline
Scientists Uncover Key Habit Behind 'SuperAgers' and Their Youthful Minds
health-and-science7 months ago

Scientists Uncover Key Habit Behind 'SuperAgers' and Their Youthful Minds

Researchers have identified that 'SuperAgers,' individuals over 80 with memory performance akin to much younger people, possess unique brain features such as resistance or resilience to Alzheimer's pathology, including thicker cortex and more von Economo neurons, which may inform future strategies to preserve cognitive function in aging.

via Earth.com|
#alzheimers-resistance#brain-aging#cognitive-health
Scientists Identify Key Habit Shared by Remarkably Sharp 80-Year-Olds
health7 months ago

Scientists Identify Key Habit Shared by Remarkably Sharp 80-Year-Olds

Research on SuperAgers—people over 80 with youthful cognitive abilities—reveals that social engagement and maintaining brain activity are key factors in preserving mental sharpness and protecting against dementia, with SuperAgers showing less brain atrophy and more social-related neurons, highlighting the importance of socializing for healthy aging.

via Women's Health|
#brain-aging#cognitive-health#dementia-prevention
Scientists Uncover Why 80-Year-Olds Have the Memory of 50-Year-Olds
health7 months ago

Scientists Uncover Why 80-Year-Olds Have the Memory of 50-Year-Olds

SuperAgers are individuals over 80 with memory performance comparable to much younger people, and their brains show unique biological traits that resist or resist the effects of Alzheimer's disease. Research suggests that social engagement, brain structure, and cellular differences contribute to their exceptional cognitive resilience, offering insights into potential ways to prevent or delay dementia.

via Science Daily|
#aging#alzheimers-prevention#brain-resilience
health-and-aging8 months ago

The Key Trait That Helps SuperAgers Live Longer

SuperAgers, individuals over 80 with memory skills comparable to much younger people, tend to live longer and healthier lives, primarily due to their strong social connections and extroverted personalities. These social habits help slow brain aging and reduce risks of diseases like dementia, which is especially significant for Black communities that face higher risks of Alzheimer's. Maintaining social interactions and a positive outlook may be key factors in their longevity and cognitive resilience.

via The Root|
#black-community#brain-health#health-and-aging