All articles tagged with #uv radiation
New findings show daily grape consumption (three servings) for two weeks alters skin gene expression and lowers UV-induced oxidative stress, suggesting grapes act as a nutrigenomic 'superfood' that could bolster the skin’s protective barrier and potentially affect other tissues.
A small study of four volunteers found that consuming about three servings of grapes daily for two weeks altered gene expression in skin cells, promoting UV-protective changes (keratinization and cornification) and reducing the oxidative stress marker malondialdehyde, suggesting grapes may confer UV protection via nutrigenomic effects; the mechanism is still unclear and findings are early, with prior data and funding from the California Table Grape Commission noted.
New research from Copenhagen and NTU Singapore shows the immediate sunburn response is driven by RNA damage, not DNA. UV exposure triggers RNA damage that activates the ribotoxic stress response via the ZAK-alpha pathway, leading to inflammation and cell death; knocking out ZAK in mice reduces these responses. This challenges long-held beliefs about UV damage and could rewrite textbooks, influence sun-protection strategies, and inspire new approaches to inflammatory skin conditions.
The FDA has withdrawn a proposed rule that would have banned tanning bed use for anyone under 18 and required parental waivers for adults, leaving regulation up to states; UV exposure from sunlamps raises skin-cancer and melanoma risk, and devices can emit up to 15 times more UV than sunlight. Warnings remain on devices, but experts debate whether warnings alone are enough without a federal ban while the agency pursues other sunlamp regulations in the future.
The FDA withdrew its 2015 proposed rule that would have barred anyone under 18 from using tanning beds, leaving regulations to state laws that already restrict or permit teen use. The withdrawal followed more than 8,100 public comments, with concerns about compliance burdens and personal choice, while authorities emphasize that UV exposure raises skin cancer risk and that sunlamps still warrant caution and potential future regulatory action.
New research finds the first UVB skin response is RNA damage that activates the ZAK alpha–driven ribotoxic stress pathway, not DNA lesions, triggering inflammation and cell death; this upends decades of DNA-centered sunburn models and could reshape dermatology education, diagnostics, and drug development, though no ZAK alpha inhibitors are in trials yet.
Scientists have discovered that sunburn damages a protective protein called YTHDF2 in skin cells, leading to uncontrolled inflammation that can trigger skin cancer. The research highlights how UV exposure breaks down YTHDF2, allowing non-coding RNAs to activate immune pathways associated with cancer development, offering new avenues for prevention and treatment.
A study by Binghamton University researchers explains that skin wrinkles with age due to repeated stretching and buckling, similar to denim creases, with changes in skin stiffness and collagen density contributing to this process. The findings provide experimental evidence of the physical mechanisms behind aging skin and have implications for skincare and understanding other tissues, as well as the impact of sun exposure on skin aging.
A Cambridge surgeon warns parents about the risks of sun exposure to children, emphasizing that repeated UV damage can lead to skin cancer later in life, and advises protective measures beyond just sunscreen.
A recent study reveals that UV and near-UV lamps used in gel manicures can chemically damage skin molecules, including enzymes like tyrosinase, leading to increased oxidative stress, potential skin aging, and higher skin cancer risk. The lamps emit UVA radiation comparable to sunlight, and repeated exposure may cause cumulative skin damage, emphasizing the need for protective measures and regulatory standards.
The New York State health department warns residents, especially families with children, about the dangers of UV radiation and skin cancer, emphasizing the importance of using broad-spectrum sunscreen with at least SPF 15 or 30, reapplying every two hours, and checking expiration dates to stay protected during the sunny summer months.
Despite airplane windows blocking most UVB rays, UVA rays can still penetrate and cause skin damage, so wearing sunscreen on flights is recommended for everyone, especially for those with higher risk factors like fair skin or a history of skin cancer.
Researchers at Tel Aviv University have discovered a new method to treat cancer by targeting a protein called Ly6a, which acts as an immune "brake". This protein, found in high levels in tumors, helps cancer evade the immune system. By using anti-Ly6a antibodies to release these brakes, the immune system can effectively attack and reduce tumors, including those resistant to current immunotherapies. The findings, published in Nature Communications, could lead to new treatments for cancer patients who do not respond to existing therapies.
Melanoma skin cancer cases in the UK are at an all-time high, with Cancer Research UK predicting 20,800 diagnoses this year. The rise is attributed to an ageing population and increased awareness of skin cancer signs. Nearly 90% of cases are linked to excessive UV radiation, and the charity emphasizes the importance of sun protection and early detection. The highest increases are seen in older adults, but younger people are more aware of UV risks. Early detection significantly improves survival rates, with almost 90% of diagnosed individuals surviving for 10 years or more.
A study published in the Journal of Investigative Dermatology reveals that ultraviolet (UV) radiation can influence subcutaneous fat regulation by increasing norepinephrine levels, which decreases leptin and promotes the browning of fat, thus enhancing energy expenditure. This discovery could lead to new treatments for obesity and metabolic disorders, although further research is needed to address the long-term effects and safety of UV exposure.