Tag

Insulin Resistance

All articles tagged with #insulin resistance

Just 80 Minutes Less Sleep Each Night Linked to Weight Gain, New Study Finds
lifestyle2 days ago

Just 80 Minutes Less Sleep Each Night Linked to Weight Gain, New Study Finds

A six‑week analysis cited in Annals of Internal Medicine shows that cutting about 80 minutes of sleep per night can cause roughly 0.45 kg (1 lb) weight gain, larger waistlines, and more sedentary behavior—even with a healthy diet and exercise. Dr. Sudhir Kumar emphasizes that sleep is a third pillar of weight management alongside diet and exercise, and most adults should aim for seven to nine hours of quality sleep nightly to protect metabolism, heart, and brain.

Desk-bound danger: long sitting linked to heart risks, cardiologists warn
health10 days ago

Desk-bound danger: long sitting linked to heart risks, cardiologists warn

Sitting for most of the day—over eight to ten hours—can raise cardiovascular risk even if you exercise, by slowing metabolism, increasing blood sugar and insulin resistance, and promoting inflammation and arterial plaque. A 2025 JACC study found risk rises sharply after about 10.6 hours of daily sitting. Experts urge regular movement breaks—stand up, walk five minutes each hour, take stairs, stretch, and move during calls—because small bursts of activity benefit the heart, though they can’t fully offset long desk hours. If your day is desk-heavy, consult a cardiologist to assess your risk.

Sugar-Free Diet in Mice Triggers Hidden Metabolic Setbacks
science24 days ago

Sugar-Free Diet in Mice Triggers Hidden Metabolic Setbacks

A 16-week mouse study found that removing sucrose from a low-fat diet disrupted gut bacteria, reduced beneficial microbes, and led to metabolic problems—impaired glucose control, insulin resistance, and fat buildup in the liver—despite similar body weight. The researchers caution that the findings, presented at ENDO 2026 and awaiting peer review, don’t yet translate to humans and suggest that completely eliminating sugar may not always be beneficial, underscoring the need to balance carbohydrates and gut health.

Going Sugar-Free May Disrupt Gut Health, Mice Show Metabolic Struggles
health29 days ago

Going Sugar-Free May Disrupt Gut Health, Mice Show Metabolic Struggles

A mouse study presented at ENDO 2026 found that removing sucrose from a low-fat diet did not improve metabolic health but disrupted the gut microbiome, caused intestinal and liver inflammation, and worsened glucose tolerance and insulin resistance, despite similar weight to controls, suggesting that completely eliminating sugar may be counterproductive and that balanced carbohydrate intake supports gut and metabolic health.

Zero-sugar, low-fat diet triggers insulin resistance in mice
health1 month ago

Zero-sugar, low-fat diet triggers insulin resistance in mice

A 16-week study in mice found that a sugar-free, low-fat diet caused impaired glucose tolerance and reduced insulin sensitivity, with inflammation in the colon and liver and signs of fatty liver disease, despite similar weight gain to controls. The sugar-free group also showed gut microbiome changes, including lower levels of beneficial Lactobacillus murinus and higher inflammatory bacteria. Findings were presented at ENDO 2026 and have not yet undergone peer review; relevance to humans remains to be determined.

PMOS: A new name for PCOS aims to improve diagnosis and care
health1 month ago

PMOS: A new name for PCOS aims to improve diagnosis and care

Experts rename polycystic ovary syndrome to polyendocrine metabolic ovarian syndrome (PMOS) to reflect its broader hormonal and metabolic features, not just ovarian cysts; diagnosis centers on irregular periods and signs of high androgens, with infertility and pregnancy risks acknowledged. Treatment emphasizes lifestyle changes and individualized options such as metformin, anti-androgens, and hormonal birth control based on fertility goals.

PMOS: A Fresh Name for PCOS Emphasizing Multisystem Metabolic Roots
health1 month ago

PMOS: A Fresh Name for PCOS Emphasizing Multisystem Metabolic Roots

PMOS, the official rename of PCOS (polycystic ovarian syndrome), reframes the condition as a multisystem endocrine and metabolic disorder driven largely by insulin resistance, not just ovarian cysts. The Lancet consensus (May 12, 2026) involved about 22,000 experts and 56 organizations to improve diagnosis, reduce stigma, and guide treatment toward metabolic health and personalized care. Diagnosis now emphasizes signs of androgen excess, menstrual history, and metabolic testing, with management focusing on lifestyle changes, glucose control, and targeted therapies, while fertility considerations are addressed when relevant. It is lifelong but manageable with proper care and advocacy.

PCOS Gets a Fresh Identity: PMOS Aims to Reflect Multisystem Roots
health2 months ago

PCOS Gets a Fresh Identity: PMOS Aims to Reflect Multisystem Roots

A global health consortium renames polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) to better capture its multisystem nature, remove the misleading focus on ovaries, and reduce stigma. After 14 years of collaboration, the group plans to push PMOS into ICD classifications within three years and raise public and professional awareness. The condition affects about 170 million people worldwide, with up to 70% undiagnosed, and often involves metabolic, endocrine, psychological, and dermatological symptoms beyond reproduction. The renaming emphasizes insulin resistance and diabetes risk, potentially guiding research, screening, and treatment, including the continued, and sometimes off-label, use of drugs like metformin. The Lancet policy paper outlines the strategy to educate globally and secure official ICD updates.

Even 'Healthy' Drinks Can Damage Your Liver, Hepatologists Warn
health2 months ago

Even 'Healthy' Drinks Can Damage Your Liver, Hepatologists Warn

Hepatologists warn that the liver can be damaged not only by alcohol but also by everyday drinks—especially fruit juice—because MASLD (metabolic dysfunction-associated steatotic liver disease) can develop from metabolic syndrome. Excessive fruit juice can cause weight gain and insulin resistance, leading to fat buildup in the liver; fiber and whole fruit help protect the liver. Limit fruit juice, read sugar content, and consult a clinician or dietitian to tailor intake.

Juice Isn’t a No-Calories Elixir: Big Study Links 100% Fruit Juice to Weight Gain
health3 months ago

Juice Isn’t a No-Calories Elixir: Big Study Links 100% Fruit Juice to Weight Gain

A large meta-analysis published in JAMA Pediatrics found that each additional daily serving of 100% fruit juice is linked to weight gain in both children and adults (about a 0.03 BMI increase per serving in kids and 0.02 in adults). Experts say this may be due to extra calories and rapidly digested sugars from juice, plus the fiber lost when juicing. The takeaway is to prioritize whole fruit, choose 100% juice with no added sugars, limit juice to roughly 4–6 ounces if you drink it, and consider diluting with sparkling water to keep portions small while still enjoying the beverage.

Seven hours of sleep linked to lower diabetes risk, study finds
health3 months ago

Seven hours of sleep linked to lower diabetes risk, study finds

A large observational study of about 25,000 people (2009–2023) found that roughly seven hours and 18 minutes of nightly sleep was associated with the lowest insulin resistance, while both shorter and longer sleep linked to worse metabolic markers; weekend catch-up sleep did not offset deficits, and self-reported data limit causal conclusions. Experts say sleep is important for metabolic health but not a standalone solution, with guidance generally suggesting about 7–9 hours of regular, high‑quality sleep to help reduce diabetes risk.